Morphometric and histopathologic evaluation of the effects of cloprostenol and equine chorionic gonadotropin administration on the reproductive organs of female rats

• Autorzy: Gurler H. , Demirel M.A. , Karaca E. , Baki Acar D. , Akcay A. , Gulbahar M.Y.
• Języki publikacji: EN

Abstrakty

EN

The aim of this study was to determine the short-, mid- and long-term effects of cloprostenol (a synthetic analogue of prostoglandin F2α, PG) and equine chorionic gonadotropin (E) administration on reproductive organs (uterine tissue and ovaries) in female rats. Three different groups, PG, E, and control (C), were created, as well as six subgroups of the PG and E groups. After the treatment procedure, reproductive organs were removed surgically 7, 14, and 21 days after the last injection. Morphometric and histopathological changes in tissues were evaluated. It was shown that PG and E had a moderate proliferative effect on epithelial cells and endometrial glands, especially in the mid-term. It was also observed that, regardless of the time of application, some pathological changes can result from hormone administration.

Słowa kluczowe

EN

morphometry; histopathology; cloprostenol; equine chorionic gonadotrophin; reproductive organ; oestrus synchronization; female; rat

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2019
• Tom: 75
• Numer: 03
• Opis fizyczny: p.169-174,fig.,ref.

Twórcy

autor

Gurler H.

• Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Ondokuz Mayis University, Samsun, Turkey

autor

Demirel M.A.

• Laboratory Animal Breeding and Experimental Research Center, Department of Pharmacology, Faculty of Pharmacy, Gazi University, Ankara, Turkey

autor

Karaca E.

• Department of Pathology, Faculty of Veterinary Medicine, Ondokuz Mayıs University, Samsun, Turkey

autor

Baki Acar D.

• Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey

autor

Akcay A.

• Department of Biometry, Faculty of Veterinary Medicine, Erciyes University, Kayseri, Turkey

autor

Gulbahar M.Y.

• Department of Pathology, Faculty of Veterinary Medicine, Ondokuz Mayıs University, Samsun, Turkey

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Identyfikatory

DOI

10.21521/mw.6195