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2012 | 15 | 1 |

Tytuł artykułu

Lymphocyte subpopulations and apoptosis of immune cells in rabbits experimentally infected with a strain of the RHD virus having a variable haemagglutination capacity

Treść / Zawartość

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The paper describes the immunological response in the matter of percentage of T cells (receptor CD5+) and subpopulations (Th with receptor CD4+, Tc/Ts with receptor CD8+, T with receptor CD25+) and B cells with receptor CD19+, as well as the percentage of apoptotic granulocytes and lymphocytes, in rabbits experimentally infected with the Hagenow strain of the RHD virus. The material chosen for the experiment is special, as among all strains of RHD virus, there are only two strains which carry the variable haemagglutination capacity of red cells. The results of the study show that the Hagenow strain gives an untypical picture of T and B lymphocytes, whereas the results in inducing apoptosis seems to corespond with previous data, confirming the inclusion of apoptosis from 4 h p.i. and the intensity of the phenomenon being higher in granulocytes.

Wydawca

-

Rocznik

Tom

15

Numer

1

Opis fizyczny

p.43-49,ref.

Twórcy

  • Department of Microbiology and Immunology, Faculty of Biology, University of Szczecin, Felczaka 3c, 71-412 Szczecin, Poland
autor

Bibliografia

  • Alonso C, Oviedo JM, Martin-Alonso JM, Diaz E, Boga JA, Parra F (1998) Programmed cell death in the pathogenesis of rabbit hemorrhagic disease. Arch Virol 143: 321-332.
  • Annon (1987) Information and training materials of the Laboratory Animals Section, General Assembly of the Association of Agriculture Engineers and Technicians, In: Materiały informacyjno-szkoleniowe Sekcji ds. Zwierząt Laboratoryjnych ZG Stowarzyszenia Inżynierów i Techników Rolnictwa, Warsaw, pp 26-77 (in Polish).
  • Annon (2006) Regulation of the Minister of Agriculture and Rural Development of 10 March 2006 on detailed conditions for maintenance of laboratory animals in experimental units, breeding units and suppliers (Polish Journal of Laws of 2006, No. 50, item 368), (in Polish).
  • Annon (2011) International Committee on Taxonomy of viruses www.icvtonline.org.com
  • Chou CT (1977) Specific surface marker of rabbit B lymphocyte – rabbit bursal equivalent lymphocyte antigen. Cell Immunol 28: 334-336.
  • Deng RT Xu YF, Yu NX (1989) Dynamic observation of RTLA and RABELA cells in the initial stage post immunisation with RHD vaccine (in Chinese). Shanghai J Anim Sci Vet Med 5: 26-28.
  • Deptuła W, Kostrzewa A, Stosik M, Tokarz-Deptuła B, Wiktorowicz K (1998) Subpopulations of peripheral blood lymphocytes in rabbits. Nowiny Lekarskie 67: 377-382.
  • Fradelizi DP (1973) Rabbit T-lymphocyte specific surface marker – rabbit thymus specific antigen (RTLA). Cell Immunol 24: 484-486.
  • Garcia-Lastra R, San-Miguel B, Crespo I, Jorquera F, Alvarez M, Gonzalez-Gallego J, Tunon M (2010) Signalling pathways involved in liver injury and regeneration in rabbit hemorrhagic disease, an animal model of virally-induced fulminant hepatic failure. Vet Res 41: 2.
  • Hukowska-Szematowicz B, Tokarz-Deptuła B, Deptuła W (2005) Lymphocytes T and their subpopulations in peripheral blood in rabbits experimentally infected with two strains of VHD virus (viral haemorrhagic disease). Pol J Environ Stud 14: 550-555.
  • Hukowska-Szematowicz B (2006) Immunological-genetic characteristics of chosen strains of RHD (rabbit haemorrhagic disease) virus. Doctoral thesis, Szczecin, Poland (in Polish).
  • Hukowska-Szematowicz B, Deptuła W (2008a) Peripheral blood lymphocytes in rabbits infected with Czech strains, CAMPV-562 and CAMPV-558 of RHD virus. Centr Eur J Immunol 33: 8-13.
  • Hukowska-Szematowicz B, Deptuła W (2008b) Dynamics of peripheral blood lymphocytes in rabbits experimentally infected with two Czech strains of RHD virus. Bull Vet Inst Pulawy 52: 23-29.
  • Jung JY, Lee BJ, Tai JH, Park JH, Lee YS (2000) Apoptosis in rabbit haemorrhagic disease. J Comp Pathol 123: 135-140.
  • Ni Z, Wei W, Liu GQ, Chen L, Yu B, Yun T, Hua JG, Li SM (2009) Studies on the apoptosis of RK13 cells induced by rabbit hemorrhagic disease virus. Bing Du Xue Bao 25: 316-317.
  • Niedźwiedzka P (2008) Immunological profile and phenomenon of apoptosis in rabbits experimentally infected with strains of RHD virus (rabbit haemorrhagic disease) with different biological features. Doctoral thesis, Szczecin, Poland (in Polish).
  • Niedźwiedzka-Rystwej P, Deptuła W (2010a) Cytometric analysis of lymphocytes T and B in rabbits infected with non-haemagglutinogenic strains of RHD virus (rabbit haemorrhagic disease) – Rainham, Frankfurt and Asturias. Pol J Vet Sci 13: 157-162.
  • Niedźwiedzka-Rystwej P, Deptuła W (2010b) Non-specific immunity in rabbits infected with 10 strains of the rabbit haemorrhagic disease virus with different biological properties. Centr Europ J Biol 5: 613-632.
  • San-Miguel B, Alvarez M, Culebras JM, Gonzalez-Gallego J, Tunon MJ (2006) N-acetyl-cysteine protects liver from apoptotic death in an animal model of fulminant hepatic failure. Apoptosis 11: 1945-1957.
  • Schirrmeier H, Reimann I, Ko¨ llner B, Granzow H (1999) Pathogenic, antigenic and molecular properties of rabbit haemorrhagic disease virus (RHDV) isolated from vaccinated rabbits: detection and characterization of antigenic variants. Arch Virol 144: 419-435.
  • Tokarz-Deptuła B, Deptuła W (2003) Dynamic alterations in peripheral blood lymphocytes in rabbits experimentally infected with VHD (viral haemorrhagic disease) virus – Polish strain Kr-1. Pol J Vet Sci 6: 67-69.
  • Tokarz-Deptuła B (2009) Immunity phenomena in rabbits infected with the RHD (rabbit haemorrhagic disease) virus. Pol J Env Stud 7: 1-81

Typ dokumentu

Bibliografia

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Identyfikator YADDA

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