EN
A prerequisite for a quantitative theory of neural coding is adequate description of spike trains. Fifty years ago it was understood that the probability to generate a spike at a given time from the stimulus onset – the post-stimulus time histogram (PSTH) – brings in useful information adding to the mean number of spikes in the trial. Today there is a growing consensus that one must go beyond the PSTH building more complex point process models of neural activity which can account, for basic physiological properties of spike fi ring, e.g. for the refractory properties or for adaptation mechanisms of the cell. We shall present some basic concepts of the point process theory in the context of the spike trains and present a simple method of estimation of a class of second order processes for stimulus-evoked activity. We will illustrate the results with an analysis of sample data from the cat superior colliculus. Supported by grants N401 146 31/3239 and 46/N-COST/2007/0.