PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2011 | 29 | 4 |
Tytuł artykułu

Polymorphism A/C in exon 7 of the bovine estrogen receptor alpha (ERalpha) gene and its association with functional and milk production traits in Red-and-White cattle

Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Due to the functions that estrogens play in the regulation of reproduction, development of mammary gland, growth and differentiation of cells, estrogen receptors and their genes are considered candidates for molecular markers of production and functional traits in farm animals. In this study,using the SSCP and DNA sequencing, we found a novel single nucleotide polymorphism (SNP) in the coding region of the estrogen receptor α (ERα) gene – the A/C transversion at position 323,396 (relative to the start of transcription site), in exon 7, that could be also detected with RFLP-CfrI.This mutation causes the amino acid replacement – Asparatic acid/Alanine in the ligand-binding domain (LBD) of the receptor.The ERα A/C (RFLP-CfrI) genotypes were estimated in a cohort of 489 cattle of different breeds,including 355 Red-and-White cows. Association was studied between ERα genotype and dairy production traits (milk yield and composition) and functional traits (reproduction, length of productive life). The results showed that ERα A/C genotype affected significantly only a few traits of interest: protein and fat content in milk, sex of calves born. No associations were detected between ERα genotype and milk yield and reproduction traits of Red-and-White cows.
Wydawca
-
Rocznik
Tom
29
Numer
4
Opis fizyczny
p.281-291,fig.,ref.
Twórcy
autor
  • Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, 05-552 Wolka Kosowska, Poland
autor
  • Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, 05-552 Wolka Kosowska, Poland
  • Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, 05-552 Wolka Kosowska, Poland
autor
  • Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, 05-552 Wolka Kosowska, Poland
  • Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, 05-552 Wolka Kosowska, Poland
Bibliografia
  • ALMEIDA S.E.M., ALMEIDA E.A., MORAES J.C.F., WEIMER T.A., 2003 − Molecular markers in the LEP gene and reproductive performance of beef cattle. Journal of Animal Breeding and Genetics 120, 106-113.
  • BLATTMAN A.N., KIRKPATRICK B.W., GREGORY K.E., 1996 − A search for quantitative trait loci for ovulation rate in cattle. Animal Genetics 27(3), 157-162.
  • BROTHERSTONE S., BANOS G., COFFEY M.P., 2002 − Evaluation of yield traits for the development of a UK fertility index for dairy cattle. World Congress on Genetics Applied to Livestock Production, Montpellier, France p. 1-28.
  • CHEN K.F., HUANG L.S., LI N., ZHANG Q., LUO M., WU C.X., 2000 − The genetic effect of estrogen receptor (ESR) on litter size traits in pig. Yi Chuan Xue Bao 27 (10), 853-857.
  • DEMATAWEWA C.M.B., BERGER P.J., 1998 − Genetic and phenotypic parameters for 305-day yield, fertility and survival in Holstein. Journal of Dairy Science 75, 2984-2989.
  • DROGEMULLER C., HAMANN H., DISTL O., 2001 − Candidate gene markers for litter size in different German pig lines. Journal of Animal Science 79 (10), 2565-2570.
  • ESSL A., 1998 − Longevity in dairy cattle breeding: a review. Livestock Production Science 57,79-89.
  • FORTES M.R., REVERTER A., ZHANG Y., COLLIS E., NAGARAJ S.H., JONSSON N.N.,PRAYAGA K.C., BARRIS W., HAWKEN R.J., 2010 − Association weight matrix for the genetic dissection of puberty in beef cattle. Proceedings of the National Academy of Sciences USA 107(31),13642-13647.
  • GIBSON J.P., JIANG Z.H., ROBINSON J.A., ARCHIBALD A.L., HALEY C.S., 2002 − No detectable association of the ESR PvuII mutation with sow productivity in a Meishan x Large White F2 population. Animal Genetics 33(6), 448-450.
  • GROEN A.F., STEINE T., COLLEAU J.J., PEDERSEN J., PRIBYL J., REINSCH N., 1997 −Economic values in dairy cattle breeding, with special reference to functional traits. Report of an EAAP-working group. Livestock Production Science 49, 1-21.
  • GROSSHANS T., XU Z.Z., BURTON L.J., JOHNSON D.L., 1996 − Genetic parameters for fertility traits in seasonal dairy cattle. Dairy Cattle Breeding in New Zealand. Proceedings of the New Zealand Society of Animal Production 56, 8-41.
  • HARGROVE G.L., KIDDY C.A., YOUNG C.W., HUNTER A.G., TRIMBERGER G.W., MATHER R.E., 1980 − Genetic polymorphisms of blood and milk and reproduction in Holstein cattle. Journal of Dairy Science 63(7), 1154-1166.
  • HOLMBERG M., ANDERSSON-EKLUND L., 2006 − Quantitative trait loci affecting fertility and calving traits in Swedish dairy cattle. Journal of Dairy Science 89, 3664‑3671.
  • JANSEN J., 1985 − Genetic aspects of fertility in dairy cattle based on analysis of A.I. data - a review with emphasis on areas for further research. Livestock Production Science 12, 1-12.
  • KANAI N., FUJII T., SAITO K., YOKOYAMA T., 1994 − Rapid and simple method for preparation of genomic DNA from easily obtainable clotted blood. Journal of Clinical Pathology 47, 1043-1044.
  • LIEFERS S.C., TE PAS M.F., VEERKAMP R.F., VAN DER LENDE T., 2002 − Associations between leptin gene polymorphisms and production, live weight, energy balance, feed intake, and fertility in Holstein heifers. Journal of Dairy Science 85(6), 1633-1638.
  • LIN C., MCALLISTER A.J., NG-KWAI-HANG K.F., HAYES J.F., BATRA T.R., LEE A.J., ROY G.L., VESELY J.A., WAUTHYM J.M, WINTER K. A., 1987 − Association of milk protein types with growth and reproductive performance of dairy heifers. Journal of Dairy Science 70(1), 29-39.
  • ROLLEROVA E., URBANCIKOVA M., 2000 − Intracellular estrogen receptors, their characterization and function (review). Endocrine Regulations 34, 203-218.
  • ROTHSCHILD M., JACOBSON C., VASKE D., TUGGLE C., WANG L., SHORT T., ECKARDTS G., SASAKI S., VINCENT A., MCLAREN SOUTHWOOD O., VAN DER STEEN H., MILEHAM A., PLASTOW G., 1996 − The estrogen receptor locus is associated with a major gene influencing litter size in pigs. Proceedings of National Academy of Sciences 93, 201-205.
  • ROYAL M.D., DARWASH A.O., FLINT A.P.E., WEBB R., WOOLLIAMS J. A., 2000 − Declining fertility in dairy cattle: changes in traditional and endocrine parameters of fertility. Animal Science 70, 487-501.
  • SMARAGDOV M.G., PRINZENBERG E.M., ZWIERZCHOWSKI L., 2006 − QTL mapping at cattle: theoretical and empirical approach. Animal Science Papers and Reports 24(2), 69-110.
  • SUWANMAJO S., BOONYANUWAT K., SUKLIM A., 2005 − Association of IGF1 and receptor genes polymorphism with fertility trait in Thai indigenous cattle. AHATBSAS International Conference, Khon Kaen University. http://www. dld.go.th.breeding/B/htm
  • SZREDER T., ZWIERZCHOWSKI L., 2004 − Polymorphism within the bovine estrogen receptoralpha gene 5′-region. Journal of Applied Genetics 45, 225-236.
  • SZREDER T., ZWIERZCHOWSKI L., 2007 − Estrogen receptors and their genes - potential markers of functional and production traits of farm animals. Molecular Biology Reports 34, 207-211.
  • TONHATI H., VASCOCELLOS F.B., ALBURQUERQUE L.G., 2000 - Genetic aspects of productive and reproductive traits in Murrah buffalo held in Sao Paulo, Brazil. Journal of Animal Breeding and Genetics 117, 333-339.
  • VAN DER WESTHUIZEN R.R., SCHOEMAN S.J., JORDAAN G.F., VAN WYCK J.B., 2000 −Heritabilities of reproductive traits in a beef cattle herd using a multitraits analysis. African Journal of Dairy Science 30(1), 140-141.
  • XU N.Y., ZHANG S.Q., PENG S.H., 2003 − Investigation on the distribution and their effects on reproduction traits of three major genes in Jinhua pigs. Yi Chuan Xue Bao 30, 1090-1096.
  • ZHANG S.J., XIONG Y.Z., DENG C.Y., ZENG F.T., QIU X.P., XIAO S.M., XIA Y., XU J. X.,RUAN Z., 2002 − Study of molecular genetics of the size of reproductive organs and litter size in the sow. Yi Chuan Xue Bao 29(12), 1073-1077.
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.agro-64063acc-506d-4fba-8f62-2e960d6f170e
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.