Wpływ mikotoksyn na zdrowie ryb

• Autorzy: Walczak M. , Jedziniak P. , Reichert M.

Warianty tytułu

EN

Influence of mycotoxins on fish health

• Języki publikacji: PL

Abstrakty

EN

Mycotoxins are a wide group of compounds that often occur in food and feeds. These toxins negatively affect living organisms and may pose a risk for consumers’ health. Fish seem to be a particularly vulnerable group because negative effects can be observed at low levels of contamination, much lower than those considered harmful for other farmed animals. Mycotoxins may disturb cellular homeostasis by their influence on cells’ metabolism, causing DNA damage and organ lesions. Moreover, they are capable of immunomodulation, which may increase the occurrence of fish diseases caused by bacteria and other pathogens. Furthermore, these substances often have a negative impact on the growth rate of fish, which may cause economic losses to farmers. Although mycotoxins are commonly found in feeds, their ability to bioaccumulate in fish seems to be marginal. Therefore, according to the available data, fish may not be considered as the main source of mycotoxins for humans. Since there are no legal limits on the amount of mycotoxins present in fish feeds, it is necessary to constantly monitor the levels of mycotoxins in fish feeds and to investigate the influence of these substances on fish health.

Słowa kluczowe

PL

akwakultury; ryby; zywienie zwierzat; pasze; zanieczyszczenia pasz; mikotoksyny; trichoteceny; aflatoksyny; zearalenon; ochratoksyny; fumonizyny; deoksyniwalenol; oddzialywanie na organizm; zdrowie zwierzat; immunomodulacja; bioakumulacja; konsumenci; czlowiek; zagrozenia zdrowia

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2018
• Tom: 74
• Numer: 03
• Opis fizyczny: s.161-166,tab.,bibliogr.

Twórcy

autor

Walczak M.

• Zakład Chorób Ryb, Państwowy Instytut Weterynaryjny - Państwowy Instytut Badawczy, Al.Partyzantów 57, 24-100 Puławy

autor

Jedziniak P.

• Zakład Farmakologii i Toksykologii, Państwowy Instytut Weterynaryjny - Państwowy Instytut Badawczy, Al. Partyzantów 57, 24-100 Puławy

autor

Reichert M.

• Zakład Chorób Ryb, Państwowy Instytut Weterynaryjny - Państwowy Instytut Badawczy, Al.Partyzantów 57, 24-100 Puławy

Bibliografia

• Anater A., Manyes L., Meca G., Ferrer E., Bittencourt Luciano F., Turra Pimpão C., Font G.: Mycotoxins and their consequences in aquaculture: A review. Aquaculture 2016, 451, 1-10.
• Antychowicz J., Pękala A.: Stres i zależne od stresu bakteryjne choroby ryb. Życie Wet. 2015, 90, 450-460.
• Arana S., Alves V. A., Sabino M., Tabata Y. A., Nonogaki S., Zaidan-Dagli M. L., Hernandez-Blazquez F. J.: Immunohistochemical evidence for myofibroblast-like cells associated with liver injury induced by aflatoxin B1 in rainbow trout (Oncorhynchus mykiss). J. Comp. Pathol. 2014, 150, 258-265.
• Bakos K., Kovács R., Staszny Á., Sipos D. K., Urbányi B., Müller F., Csenki Z., Kovács B.: Developmental toxicity and estrogenic potency of zearalenone in zebrafish (Danio rerio). Aquat. Toxicol. 2013, 15, 13-21.
• Bennett J. W., Klich M.: Mycotoxins. Clin. Microbiol. Rev. 2003, 16, 497-516.
• Deng S. X., Tian L. X., Liu F. J., Jin S. J., Liang G. Y., Yang H. J., Du Z. Y., Liu Y. J.: Toxic effects and residue of aflatoxin B1 in tilapia (Oreochromis niloticus × O. aureus) during long-term dietary exposure. Aquaculture 2010, 307, 233-240.
• Döll S., Valenta H., Baardsen G., Möller P., Koppe W., Stubhaug I., Dänicke S.: Effects of Increasing Concentrations of Deoxynivalenol, Zearalenone and Ochratoxin A in Diets for Atlantic Salmon (Salmo salar) on Performance, Health and Toxin Residues. Proc. 33rd Mycotoxin Workshop, Freising, Germany, 30 May–1 June 2011, s. 24.
• EFSA CONTAM Panel (EFSA Panel on Contaminants in the Food Chain), 2014. Scientific Opinion on the risks for human and animal health related to the presence of modified forms of certain mycotoxins in food and feed. EFSA Journal 2014, 12, 3916.
• EFSA CONTAM Panel: Opinion of the Scientific Panel on Contaminants in Food Chain on a request from the Commission related to fumonisins as undesirable substances in animal feed. EFSA Journal 2005, 235, 1-32.
• El-Moselhy Kh. M., Othman A. I., Abd El-Azem H., El-Metwally M. E. A.: Bioaccumulation of heavy metals in some tissues of fish in the Red Sea, Egypt, Egypt. J. Basic Appl. Sci. 2014, 1, 97-105.
• El-Sayed Y. S., Khalil R. H.: Toxicity, biochemical effects and residue of aflatoxin B1 in marine water-reared sea bass (Dicentrarchus labrax L.). Food Chem. Toxicol. 2009, 47, 1606-1609.
• El-Sayed Y. S., Khalil R. H., Saad T. T.: Acute toxicity of ochratoxin-A in marine water-reared sea bass (Dicentrarchus labrax L.). Chemosphere 2009, 75, 878 -882.
• Gbore F. A., Adewole A. M., Oginni O., Oguntolu M. G., Bada A. M., Akele O.: Growth performance, haematology and serum biochemistry of African catfish (Clarias gariepinus) fingerlings fed graded levels of dietary fumonisin B1. Mycotoxin Res. 2010, 26, 221-227.
• Goncalves R. A., Naehrer K., Santos G. A.: Occurrence of mycotoxins in commercial aquafeeds in Asia and Europe: a real risk to aquaculture? Rev. Aquacult. 2016, 1, 1-18.
• Greco M., Pardo A., Pose G.: Mycotoxigenic fungi and natural co-occurrence of mycotoxins in rainbow trout (Oncorhynchus mykiss) feeds. Toxins (Basel) 2015, 7, 4595-4609.
• Haq M., Gonzalez N., Mintz K., Jaja-Chimedza A., De Jesus C. L., Lydon C., Welch A., Berry J. P.: Teratogenicity of Ochratoxin A and the Degradation Product, Ochratoxin α, in the Zebrafish (Danio rerio) Embryo Model of Vertebrate Development. Toxins (Basel) 2016, 8, 40.
• He C. H., Fan Y. H., Wang Y., Huang C. Y., Wang X. C., Zhang H. B.: The Individual and Combined Effects of Deoxynivalenol and Aflatoxin B1 on Primary Hepatocytes of Cyprinus carpio. Internat. J. Mol. Sci. 2010, 11, 3760-3768.
• Hooft J. M., Elmor A. E. H. I., Encarnação P., Bureau D. P.: Rainbow trout (Oncorhynchus mykiss) is extremely sensitive to the feed-borne Fusarium mycotoxin deoxynivalenol (DON). Aquaculture 2011, 311, 224-232.
• Kosicki R., Błajet-Kosicka A., Grajewski J., Twarużek M.: Multiannual mycotoxin survey in feed materials and feedingstuffs. Anim. Feed Sci. Technol. 2016, 215, 165-180.
• Kovacić S., Pepeljnjak S., Petrinec Z., Klarić M. S.: Fumonisin B1 neurotoxicity in young carp (Cyprinus carpio L.) Arh. Hig. Rada Toksikol. 2009, 60, 419-426.
• Lumbertdacha S., Lovell R. T., Shelby R. A., Lenz S. D., Kemppainen B. W.: Growth, hematology, and histopathology of channel catfish, Ictalurus punctatus, fed toxins from Fusarium moniliforme. Aquaculture 1995, 130, 201-218.
• Madhusudhanan N., Kavithalakshmi S. N., Shanmugasundaram E. R., Shanmugasundaram K. R.: Aflatoxin B1-induced DNA damage in Labeo rohita: protective effect of an antioxidant supplement, Amrita Bindu. Basic Clin. Pharmacol. Toxicol. 2006, 98, 473-479.
• Manning B. B., Ulloa R. M., Li M. H., Robinson E. H., Rottinghaus G. E.: Ochratoxin A fed to channel catfish (Ictalurus punctatus) causes reduced growth and lesions of hepatopancreatic tissue. Aquaculture 2003, 219, 739-750.
• Matejova I., Vicenova M., Vojtek L., Kudlackova H., Nedbalcova K., Faldyna M., Sisperova E., Modra H., Svobodova Z.: Effect of the mycotoxin deoxynivalenol on the immune responses of rainbow trout (Oncorhynchus mykiss). Veterinarni Medicina 2015, 60, 515-521.
• Pelyhe C., Kövesi B., Zándoki E., Kovács B., Szabó-Fodor J., Mézes M., Balogh K.: Effect of 4-week feeding of deoxynivalenol- or T-2-toxincontaminated diet on lipid peroxidation and glutathione redox system in the hepatopancreas of common carp (Cyprinus carpio L.). Mycotoxin Res. 2016, 32, 77-83.
• Petrinec Z., Pepeljnjak S., Kovacic S., Krznaric A.: Fumonisin B., causes multiple lesions in common carp (Cyprinus carpio), Dtsch. tierarztl. Wschr. 2004, 111, 341-380.
• Pietsch C., Junge R.: Physiological responses of carp (Cyprinus carpio L.) to dietary exposure to zearalenone (ZEN). Comp. Biochem. Physiol. C: Toxicol Pharmacol. 2016, 188, 52-59.
• Pietsch C., Junge R., Burkhardt-Holm P.: Immunomodulation by Zearalenone in Carp (Cyprinus carpio L.). Biomed. Res. Int. 2015, doi: 10.1155/2015/420702.
• Pietsch C., Katzenback B. A., Garcia-Garcia E., Schulz C., Belosevic M., Burkhardt-Holm P.: Acute and subchronic effects on immune responses of carp (Cyprinus carpio L.) after exposure to deoxynivalenol (DON) in feed. Mycotoxin Res. 2015, 31,151-164.
• Pietsch C., Kersten S., Burkhardt-Holm P., Valenta H., Dänicke S.: Occurrence of Deoxynivalenol and Zearalenone in Commercial Fish Feed: An Initial Study. Toxins 2013, 5, 184-192.
• Pietsch C., Kersten S., Valenta H., Dänicke S., Schulz C., Burkhardt-Holm P., Junge R.: Effects of Dietary Exposure to Zearalenone (ZEN) on Carp (Cyprinus carpio L.) Toxins (Basel) 2015, 7, 3465-3480.
• Pietsch C., Michel C., Kersten S., Valenta H., Dänicke S., Schulz C., Kloas W., Burkhardt-Holm P.: In vivo effects of deoxynivalenol (DON) on innate immune responses of carp (Cyprinus carpio L.). Food Chem. Toxicol. 2014, 68, 44-52.
• Pietsch C., Schulz C., Rovira P., Kloas W., Burkhardt-Holm P.: Organ Damage and Hepatic Lipid Accumulation in Carp (Cyprinus carpio L.) after Feed-Borne Exposure to the Mycotoxin, Deoxynivalenol (DON). Toxins 2014, 6, 756-778. doi:10.3390/toxins6020756.
• Sahoo P. K., Mukherjee S. C.: Immunosuppressive effects of aflatoxin B1 in Indian major carp (Labeo rohita). Comp. Immunol. Microbiol. Infect. Dis. 2001, 24, 143-149.
• Sanden M., Jorgensen S., Hemre G. I., Ornrud R., Sissener N. H.: Zebrafish (Danio rerio) as a model for investigating dietary toxic effects of deoxynivalenol contamination in aquaculture feeds. Food Chem. Toxicol. 2012, 50, 4441-4448.
• Tuan N. A., Manning B. B., Lovell R. T., Rottinghaus G. E.: Responses of Nile tilapia (Oreochromis niloticus) fed diets containing different concentrations of moniliformin or fumonisin B1. Aquaculture 2003, 217, 515-528.
• Veras F. F., Correa A. P., Welke J. E., Brandelli A.: Inhibition of mycotoxin-producing fungi by Bacillus strains isolated from fish intestines. Int. J. Food Microbiol. 2016, 238, 23-32.
• Walczak M., Reichert M.: Characteristics of selected bioaccumulative substances and their impact on fish health. J. Vet. Res. 2016, 60, 473-480.
• Woźny M., Obremski K., Jakimiuk E., Gusiatin M., Brzuzan P.: Zearalenone contamination in rainbow trout farms in north-eastern Poland. Aquaculture 2013, 416-417, 209-211.
• Zalecenie Komisji z dnia 17 sierpnia 2006 w sprawie obecności deoksyniwalenolu, zearalenonu, ochratoksyny A, T-2 i HT-2 oraz fumonizyn w produktach przeznaczonych do żywienia zwierząt. Dziennik Urzędowy Komisji Europejskiej L 229/7.
• Zinedine A., Soriano J. M., Moltó J. C., Mañes J.: Review on the toxicity, occurrence, metabolism, detoxification, regulations and intake of zearalenone: an oestrogenic mycotoxin. Food Chem. Toxicol. 2007, 45, 1-18.

Identyfikatory

DOI

10.21521/mw.6052