Age-related histopathological changes in the cardiac conducting system in the Turkish population: an evaluation of 202 autopsy cases

• Autorzy: Comunoglu C. , Comunoglu N. , Eren B. , Tanriover O. , Turkmen N. , Gundogmus U. N. , Eren F.
• Języki publikacji: EN

Abstrakty

EN

Background: Histopathological features of the cardiac conducting system (CCS) in the Turkish population have not been investigated previously. Material and methods: We examined CCS of 202 autopsy heart specimens dissected between the years 2004 and 2005 in Bursa Forensic Medicine Institution. Of the 202 cases from all age groups, 154 were males and 48 were females. Results: In our cases, an increase in fibrous and adipose tissue concordant with age, indicating an age-related nature, were detected. Fibrous and fatty tissue infiltration appeared at the age of 35. Fatty infiltration started between the ages 20 and 34 years at the sinoatrial node (SAN). There was no relationship between obesity and fatty tissue infiltration in SAN and atrioventricular node (AVN). In 4 cases calcification and in 19 cases inflammation was observed. Amyloid accumulation was not present. In 7 cases myocardial infarction not involving CCS was seen. In 1 case fibroelastoma was detected. Conclusions: In the Turkish population age-related fibrosis and fatty infiltration in CCS appeared at the age of 35 years and increased with age. Fatty infiltration in the SAN started at a younger age than that reported in the literature. In cases where the cause of death could not be determined, we could not detect lethal pathological features. However, we think that examination of the CCS will improve the quality of autopsy diagnosis. (Folia Morphol 2012; 71, 3: 178–182)

• Wydawca: -
• Czasopismo: Folia Morphologica
• Rocznik: 2012
• Tom: 71
• Numer: 3
• Opis fizyczny: p.178-182,fig.,ref.

Twórcy

autor

Comunoglu C.

• Near East University Faculty of Medicine, Department of Pathology, Nicosia, Near East Blv. Nicosia, North Cyprus, Mersin-10, Turkey

autor

Comunoglu N.

• Haydarpaşa Numune Hospital, Department of Pathology, Istanbul, Turkey

autor

Eren B.

• Bursa Morgue Department, Forensic Medicine, Bursa, Turkey

autor

Tanriover O.

• Yeditepe University, Faculty of Medicine, Department of Family Medicine, Istanbul, Turkey

autor

Turkmen N.

• Uludag University Faculty of Medicine, Department of Forensic Medicine, Bursa, Turkey

autor

Gundogmus U. N.

• Istanbul University, Forensic Medicine Institute, Istanbul, Turkey

autor

Eren F.

• Sevket Yllmaz Research and Training Hospital, Department of Pathology, Bursa, Turkey

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