Changes in selected biochemical blood parameters following various methods of postpartum hypocalcaemia prophylaxis

• Autorzy: Kurek L. , Lutnicki K. , Olech M. , Brodzki P. , Marczuk J. , Golynski M.
• Języki publikacji: EN

Abstrakty

EN

The current methods of preventing calcium deficiency during the periparturient period are based primarily on a diet low in calcium and acidifying the rumen content before parturition, as well as on oral administration of liquid preparations or boluses. The available literature does not provide information on whether these forms of prevention are effective only immediately after the parturition, or whether they also affect an organism throughout the initial lactation period. The aim of the study was to examine the effects of three methods for the prevention of postpartum hypocalcaemia on selected indicators of mineral and energy metabolism, as well as on functional parameters of the parenchymal organs during the two week period following parturition in dairy cows diagnosed with low calcium concentrations before parturition, induced by a lower dietary mineral content. The study was conducted in 60 HF cows, aged 3-6 years old, fed TMR. The animals were divided into three groups: the first group received only a mineral preparation contained in the feed, adjusted to the physiological stage and milk production level; the second group received three additional doses (directly before the parturition, then 24 hours and 48 hours after the delivery) of an oral fluid preparation containing 62.5 g of Ca; while the third group received an intraruminal bolus containing 43 g of pure calcium (immediately after parturition). This research showed that physiological hypocalcaemia occurred at the beginning of lactation in the groups which had received additional calcium preparations (groups II and III), whereas in group I blood collection one week and two weeks after the parturition demonstrated subclinical hypocalcaemia. A statistically significant increase in magnesium and a decrease in phosphorus concentrations were also observed in the latter group, as well as an excessive GGTP activity and high bilirubin concentrations. Using only one complex mineral supplement in high yielding milk cows after parturition does not ensure the expected prophylactic effects, especially in the long term.

Słowa kluczowe

EN

biochemical parameter; blood parameter; postnatal period; prophylaxis; hypocalcaemia; dairy cattle; cow; macroelement

• Wydawca: -
• Czasopismo: Journal of Elementology
• Rocznik: 2016
• Tom: 21
• Numer: 1
• Opis fizyczny: p.77-87,ref.

Twórcy

autor

Kurek L.

• Sub-Department of Internal Diseases of Farm Animals and Horses, Department and Clinic of Animal Internal Medicine, University of Life Science in Lublin, Gleboka 30, 20-612 Lublin, Poland

autor

Lutnicki K.

• Sub-Department of Internal Diseases of Farm Animals and Horses, Department and Clinic of Animal Internal Medicine, University of Life Science in Lublin, Lublin, Poland

autor

Olech M.

• Sub-Department of Internal Diseases of Farm Animals and Horses, Department and Clinic of Animal Internal Medicine, University of Life Science in Lublin, Lublin, Poland

autor

Brodzki P.

• Department and Clinic of Reproduction, University of Life Science in Lublin, Lublin, Poland

autor

Marczuk J.

• Sub-Department of Internal Diseases of Farm Animals and Horses, Department and Clinic of Animal Internal Medicine, University of Life Science in Lublin, Lublin, Poland

autor

Golynski M.

• Sub-Department of Internal Diseases of Farm Animals and Horses, Department and Clinic of Animal Internal Medicine, University of Life Science in Lublin, Lublin, Poland

Bibliografia

• Beede, D.K., Risco C.A., Donovan G.A., Wang C., Arch bald L.F., Sanch ez W.K. 1992. Nutritional management of the late pregnant dry cow with particular reference to dietary cation-anion difference and calcium supplementation. Bov. Proc., 24: 51-55.
• Cebra C.K., Garry F.B., Getzy D.M., Fettman M.J. 1997. Hepatic lipidosis in anorectic, lactating Holstein cattle: A retrospective study of serum biochemical abnormalities. J. Vet. Intern. Med., 11: 231-237.
• Chamberlin W.G., Middleton J.R., Spain J.N., Johnson G.C., Ellersieck M.R. Pithua P. 2013. Subclinical hypocalcemia, plasma biochemical parameters, lipid metabolism, postpartum disease, and fertility in postparturient dairy cows. J. Dairy Sci., 96: 7001-7013.
• Chapinal N., Carson M.E., Duffield T.F., Capel M., Godden S., Overton M., Santos J.E., Le Blanck S.J. 2011. The association of serum metabolites with clinical disease during the transition period. J Dairy Sci., 94: 4897-4903.
• Charbonneau, E., Pellerin D., and Oetzel G.R. 2006. Impact of lowering dietary cation-anion difference in nonlactating dairy cows: A meta-analysis. J. Dairy Sci., 89: 537-548.
• DeGaris P.J., Lean I.J. 2009. Milk fever in dairy cows: A review of pathophysiology and control principles. Vet. J., 176: 58-69.
• Gelfert, C.C., Loeffler L.M., Fromer S., Engel M., Manner K., Staufenbiel R. 2010. Comparison of the impact of different anionic salts on the acid-base status and calcium metabolism in non-lactating, non-pregnant dairy cows. Vet. J., 185: 305-309.
• Goff J.P. 2006. Macromineral physiology and application to the feeding of the dairy cow for prevention of milk fever and other periparturient mineral disorders. Anim. Feed Sci. Technol., 126: 237-257.
• Goff J.P. 2008. The monitoring, prevention, and treatment of milk fever and subclinical hypocalcaemia in dairy cows. Vet. J., 176: 50-57.
• Goff, J.P., Horst R.L. 1993. Oral administration of calcium salts for treatment of hypocalcemia in cattle. J. Dairy Sci., 76: 101-108.
• Goff, J.P., Horst R. L. 1994. Calcium salts for treating hypocalcemia: Carrier effects, acid-base balance, and oral versus recital administration. J. Dairy Sci., 77: 1451-1456.
• Goff J.P., Horst R.L. 1997. Physiological changes at parturition and their relationship to metabolic disorders. J. Dairy Sci., 80: 1260-1268.
• Goff, J.P., Ruiz R., Horst R.L. 2004. Relative acidifying activity of anionic salts commonly used to prevent milk fever. J. Dairy Sci., 87: 1245-1255.
• Horst R.L., Goff J.P., McCluskey B. 2003. Prevalence of subclinical hypocalcemia in U.S. dairy operation. US Department of Agriculture (USDA) Agricultural Research Service, Washington, DC.
• Horst R.L., Goff J.P., Reinhardt T.A., Buxton D.R. 1997. Strategies for preventing milk fever in dairy cattle. J. Dairy Sci., 80: 1269-1280.
• Houe H., Ostergaard S., Thilsing-Hansen T., Jorgensen R.J., Larsen T., Sorensen J.T., Agger J.F., Blom J.Y. 2001. Milk fever and subclinical hypocalcaemia – an evaluation of parameters on incidence risk, diagnosis, risk factors and biological effects as input for a decision support system for disease control. Acta Vet. Scand., 42: 1-29.
• Jawor P.E., Huzzey J.M., LeBlanck S.J., von Keyserlingk M.A.G. 2012. Associations of subclinical hypocalcemia at calving with milk yield, and feeding, drinking, and standing behaviors around parturition in Holstein cows. J. Dairy Sci., 95: 1240-1248.
• Kronqvist C., Emanuelson U., Spörndly R., Holtenius K. 2011. Effects of prepartum dietary calcium level on calcium and magnesium metabolizm in periparturient dairy cows. J. Dairy Sci., 94: 1365-1373.
• Lean J., DeGaris P.J., McNeill D.M., Block E. 2006. Hypocalcemia in dairy cows: Metanalisys and dietary cation anion difference theory revisited. J. Dairy Sci., 89: 669-684.
• Martinez N., Risco C.A., Lima F.S., Bisinotto R.S., Greco L.F., Ribeiro E.S., Manusell F., Galvão K., Santos J.E.P. 2012. Evaluation of peripartal calcium status, energetic profile, and neutrophil function in dairy cows at low or high risk of developing uterine disease. J. Dairy Sci., 95: 7158-7172.Moore S.J., VandeHaar M.J., Sharma B.K., Pilbeam T.E., Beede D.K., Buch oltz H.F., Liesman J.S., Horst R.L., Goff J.P. 2000. Effects of altering dietary cation – anion difference on calcium and energy metabolism in peripartum cows. J. Dairy Sci., 83: 2095-2104.
• Mulligan F.J., O’Grady L., Rice D., Doherty M.L. 2006. Production diseases of the transition cow: Milk Fever and subclinical hypocalcaemia. Irish Vet. J., 59: 697-702.
• Mulligan F.J., Doherty M.L. 2008. Production diseases of the transition cow. Vet. J., 176: 3-9.
• Murray R.D., Horsfield J.E., McCormick W.D., Williams H.J., Ward D. 2008. Historical and current perspectives on the treatment, control and pathogenesis of milk fever in dairy cattle. Vet. Rec., 163(19): 561-565.
• Oetzel G.R. 2004. Monitoring and testing dairy herds for metabolic disease. Vet. Clin. North Am. Food Anim. Pract., 20: 651-674.
• Pehrson, B., Jonsson M. 1991. Prevention of milk fever by oral administration of encapsulated Ca-salts. Bov. Pract., 26: 36-37.
• Ramos-Nieves, J. M., Thering B.J., Waldron M.R., Jardon P.W., Overton T.R. 2009. Effects of anion supplementation to low potassium prepartum diets on macromineral status and performance of periparturient dairy cows. J. Dairy Sci., 92: 5677-5691.
• Reinhardt T.A., Lippolis J.D., McCluskey B.J., Goff J.P, Horst R.L. 2011. Prevalence of subclinical hypocalcemia in dairy herds. Vet. J., 188: 122-4.
• Roch e J.R. 2003. The incidence and control of hypocalcaemia in pasture-based systems. Acta Vet. Scand. Suppl., 97: 141-144.
• Sahinduran S., Sezer K., Buyukoglu T., Albay M. K., Karakurum M. C. 2010. Evaluation of some haematological and biochemical parameters before and after treatment in cows with ketosis and comparison of different treatment methods. J. Anim. Vet. Adv., 9: 266-271.
• Sampson J.D., S pain J.N., Jones C., Carstensen L. 2009. Effects of calcium chloride and calcium sulfate in an oral bolus given as a supplement to postpartum dairy cows. Vet. Ther., 10: 131-139.
• Sobiech P., Rypuła K., Wojewoda-Kotwica B., Michalsk i S. 2010. Usefulness of calcium-magnesium products in parturientparesis in HF cows. J. Elem., 15(4): 693-704.
• Steen A. 2001. Field study of dairy cows with reduced appetite in early lactation: clinical examinations, blond and rumen fluid analyses. Acta Vet. Scand., 42: 219-228.
• Thilsing-Hansen T., Jørgensen R.J., Østergaard S. 2002. Milk fever control principles: a review. Acta Vet. Scand., 43: 1-19. Van den Top A.M., Geelen M.J.H., Wensing T., Wentink G.H., Van’t Klooster A.T., Beynen C. 1996. Higher postpartum hepatic triacylglycerol concentrations in dairy cows with rather than restricted access to feed during the dry period are associated with lower activities of hepatic glycerolphosphate acyltransferase. J. Nutr., 126: 76-85.
• Winnick a A. 2011. Reference values of basic laboratory examinations in veterinary medicine. Ed. SGGW, Warszawa. (in Polish)
• Zelený T., Zelený J., Kroupová P., Slavík P. 2007. Dynamics of calcaemia, phosphoraemia and magnesaemia at different prepartal intakes of calcium in dairy cows. Acta Vet. Brno, 76: 187-193.

Identyfikatory

DOI

10.5601/jelem.2015.20.2.870