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2015 | 71 | 02 |

Tytuł artykułu

Zakażenia cirkowirusowe świń - aktualna klasyfikacja oraz kryteria diagnostyczne

Warianty tytułu

EN
Circovirus infections in pigs - current terminology and diagnostic criteria

Języki publikacji

PL

Abstrakty

EN
Porcine circovirus type 2 (PCV2) belongs to the Circoviridae family, comprising the smallest viral pathogens. PCV2 is involved in the etiology of several diseases of swine called “porcine circovirus associated disease” (PCVD). The most important disease in this group is postweaning multisystemic wasting syndrome (PMWS). The role of PCV2 in the etiology of PCVD and the ambiguous interpretation of laboratory results have for years been subjects of controversy. Several, interchangeably used, names have been created for clinical syndromes related to PCV2, and unclear diagnostic criteria hampered the identification of diseases. Therefore, in 2012, new terminology and standardized diagnostic rules were proposed for clinical syndromes related to PCV2. The diagnosis of PCV2 systemic disease and of other PCV2-related diseases is based on the detection of the virus associated with characteristic histopathological lesions (by in situ hybridization or immunohistochemistry). Currently, 4 vaccines for PCV2 immunoprophylaxis are commercially available. The dominant genotype is PCV2b, and its prevalence has also been confirmed in Poland. However, all commercially available vaccines are based on the PCV2a genotype. The latest results, published in 2013, indicate that experimental vaccines based on the PCV2b genotype are more effective and offer better protection against infections with PCV2b alone and those involving both PCV2b and PCV2a compared to commercially available vaccines.

Wydawca

-

Rocznik

Tom

71

Numer

02

Opis fizyczny

s.88-93,tab.,bibliogr.

Twórcy

  • Zakład Chorób Świń, Państwowy Instytut Weterynaryjny - Państwowy Instytut Badawczy w Puławach, Al.Partyzantów 57, 24-100 Puławy
autor
  • Zakład Chorób Świń, Państwowy Instytut Weterynaryjny - Państwowy Instytut Badawczy w Puławach, Al.Partyzantów 57, 24-100 Puławy

Bibliografia

  • 1. Allan G., Krakowka S., Ellis J.: PCV2: ticking time bomb? Pig Progress 2002, 18, 14-15.
  • 2. Allan G., McNeilly F., Kennedy S., Daft B., Clarke E. G., Ellis J. A., Haines D. M., Meehan B. M., Adair B. M.: Isolation of porcine circovirus-like virusesfrom pigs with a wasting disease in the USA and Europe. J. Vet. Diagn. Invest.1998, 10, 3.
  • 3. Chae C.: A review of porcine circovirus 2-associated syndromes and diseases. Vet. J. 2005, 169, 326-336.
  • 4. Dvorak C. M., Lilla M. P., Baker S. R., Murtaugh M. P.: Multiple routes of porcine circovirus type 2 transmission to piglets in the presence of maternalimmunity. Vet. Microbiol. 2012, 166, 365-374.
  • 5. Fabisiak M., Szczotka A., Podgórska K., Stadejek T.: Prevalence of infection and genetic diversity of porcine circovirus type 2 (PCV2) in wild boar (Susscrofa) in Poland. J. Wildl. Dis. 2012, 48, 612-618.
  • 6. Fraile L., Grau-Roma L., Sarasola P., Sinovas N., Nofrarías M., López- Jimenez R., López-Soria S., Sibila M., Segalés J.: Inactivated PCV2 one shot vaccine applied in 3-week-old piglets: improvement of productionparameters and interaction with maternally derived immunity. Vaccine 2012,30, 1986-1992.
  • 7. Grau-Roma L., Segalés J.: Detection of porcine reproductive and respiratory syndrome virus, porcine circovirus type 2, swine influenza virus and Aujeszky’sdisease virus in cases of porcine proliferative and necrotizing pneumonia (PNP)in Spain. Vet. Microbiol. 2007, 119, 144-151.
  • 8. Hamel A., Lin L. L., Nayar G. P.: Nucleotide sequence of porcine circovirus associated with postweaning multisystemic wasting syndrome in pigs. J. Virol. 1998, 72, 5262-5267.
  • 9. Jakobsen B., Krueger L., Seeliger F., Bruegmann M., Segalés J., Baumgaertner W.: Retrospective study on the occurrence of porcine circovirus 2 infectionand associated entities in northern Germany. Vet. Microbiol. 2009, 138, 27-33.
  • 10. Jensen T. K., Vigre H., Svensmark B., Bille-Hansen V.: Distinction between porcine circovirus type 2 enteritis and porcine proliferative enteropathy causedby Lawsonia intracellularis. J. Comp. Pathol. 2006, 135, 176-182.
  • 11. Kekarainen T., McCullough K., Fort M., Fossum C., Segalés J., Allan G. M.: Immune responses and vaccine-induced immunity against Porcine circovirustype 2. Vet. Immunol. Immunopathol. 2010, 136, 185-193.
  • 12. Kurmann J., Sydler T., Brugnera E., Buergi E., Haessig M., Suter M., Sidler X.: Vaccination of dams increases antibody titer and improves growth parametersin finisher pigs subclinically infected with porcine circovirus type 2. Clin.Vaccine Immunol. 2011, 18, 1644-1649.
  • 13. Madec F., Eveno E., Morvan P., Hamon L., Blanchard P., Cariolet R., Amenna N., Morvan H., Truong C., Mahé D., Albina E., Jestin A.: Post-weaning multisystemicwasting syndrome (PMWS) in pigs in France: clinical observationsfrom follow-up studies on affected farms. Livest. Prod. Sci. 2000, 63, 223-233.
  • 14. McNeilly F., McNair I., O’Connor M., Brockbank S., Gilpin D., Lasagna C., Boriosi G., Meehan B., Ellis J., Krakowka S., Allan G. M.: Evaluation of a porcine circovirus type 2-specific antigen-capture enzyme-linked immunosorbentassay for the diagnosis of postweaning multisystemic wasting syndromein pigs: comparison with virus isolation, immunohistochemistry, and the polymerase chain reaction. J. Vet. Diagn. Invest. 2002, 14, 106-112.
  • 15. Meehan B. M., McNeilly F., Todd D., Kennedy S., Jewhurst V. A., Ellis J. A., Hassard L. E., Clark E. G., Haines D. M., Allan G. M.: Characterization ofnovel circovirus DNAs associated with wasting syndromes in pigs. J. Gen.Virol. 1998, 79, 2171-2179.
  • 16. Opriessnig T., Halbur P.: Concurrent infections are important for expression of porcine circovirus associated disease. Virus Res. 2012, 164, 20-32.
  • 17. Opriessnig T., Meng X. J., Halbur P. G.: Porcine circovirus type 2 associated disease: update on current terminology, clinical manifestation, pathogenesis,diagnosis, and intervention strategies. J. Vet. Diagn. Invest. 2007, 19, 591-615.
  • 18. Opriessnig T., O’Neill K., Gerber P. F., de Castro A. M., Gimenéz-Lirola L. G., Beach N. M., Zhou L., Meng X. J., Wang C., Halbur P. G.: A PCV2 vaccinebased on genotype 2b is more effective than a 2a-based vaccine to protectagainst PCV2b or combined PCV2a/2b viremia in pigs with concurrent PCV2,PRRSV and PPV infection. Vaccine 2013, 31, 487-494.
  • 19. Opriessnig T., Xiao C. T., Gerber P. F., Halbur P. G.: Emergence of a novel mutant PCV2B variant associated with clinical PCVAD in two vaccinated pigfarms in the U.S. concurrently infected with PPV2. Vet. Microbiol. 2013, 163,177-183.
  • 20. Pejsak Z.: Ochrona zdrowia świń. Polskie Wydawnictwo Rolnicze, Poznań 2007, s. 151.
  • 21. Pejsak Z., Kusior G., Pomorska-Mól M., Podgórska K.: Influence of longterm vaccination of a breeding herd of pigs against PCV2 on reproductiveparameters. Pol. J. Vet. Sci. 2012, 15, 37-42.
  • 22. Pejsak Z., Podgórska K., Truszczyński M., Karbowiak P., Stadejek T.: Efficacy of different protocols of vaccination against porcine circovirus type 2 (PCV2)in a farm affected by postweaning multisystemic wasting syndrome (PMWS).Comp. Immunol. Microbiol. Infect. Dis. 2010, 33, 1-5.
  • 23. Podgórska K.: Opracowanie i zastosowanie metod rozpoznawania zakażeń cirkowirusem świń typu 2 (PCV2). Praca dokt., Zakład Chorób Świń, PIWet--PIB, Puławy 2008.
  • 24. Prickett J. R., Johnson J., Murtaugh M. P., Puvanendiran S., Wang C., Zimmerman J. J., Opriessnig T.: Prolonged detection of PCV2 and anti-PCV2antibody in oral fluids following experimental inoculation. Transbound. Emerg.Dis. 2011, 11.
  • 25. Rodríguez-Arrioja G. M., Segalés J., Calsamiglia M., Resendes A. R., Balasch M., Plana-Duran J., Casal J., Domingo M.: Dynamics of porcine circovirus type 2 infection in a herd of pigs with postweaning multisystemic wasting syndrome. Am. J. Vet. Res. 2002, 63, 354-357.
  • 26. Segalés J.: Porcine circovirus type 2 (PCV2) infections: Clinical signs, pathology and laboratory diagnosis. Virus Res. 2012, 164, 10-19.
  • 27. Segalés J., Allan G. M., Domingo M.: Porcine circovirus diseases. Anim. Health Res. Rev. 2005, 6, 119-142.
  • 28. Segalés J., Domingo M.: Postweaning multisystemic wasting syndrome (PMWS) in pigs. A review. Vet. Q. 2002, 24, 109-124.
  • 29. Ticó G., Segalés J., Martínez J.: The blurred border between porcine circovirus type 2-systemic disease and porcine respiratory disease complex. Vet.Microbiol. 2013, 163, 242-247.
  • 30. Young M. G., Cunningham G. L., Sanford S. E.: Circovirus vaccination in pigs with subclinical porcine circovirus type 2 infection complicated by ileitis. J. Swine Health Prod. 2011, 19, 175-180.

Typ dokumentu

Bibliografia

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