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2012 | 68 | 03 |

Tytuł artykułu

Biogeneza kuleczek tłuszczowych mleka

Warianty tytułu

EN
Biogenesis of the milk fat globules

Języki publikacji

PL

Abstrakty

EN
Processes of milk fat biosynthesis and milk fat globules secretion are gaining increasing attention in recent years. Milk fat not only provides calories and nutritionally important components, but also greatly contributes to the organoleptic characteristics of dairy products. Milk fat globules are formed and secreted from mammary epithelial cells. The functioning and development of the mammary gland is a very complex process. The changes in hormonal levels upon each pregnancy cause the mammary epithelial cells to proliferate, differentiate and die due to apoptosis. The paper brings together current information regarding the regulation of the mammary gland development, regulation of milk fat synthesis, as well as characterizes key stages in the biosynthesis, formation and secretion of milk fat globules.

Wydawca

-

Rocznik

Tom

68

Numer

03

Opis fizyczny

s.163-167,bibliogr.

Twórcy

  • Katedra Mleczarstwa i Zarządzania Jakością, Wydział Nauki o Żywności, Uniwersytet Warmińsko-Mazurski w Olsztynie, ul.Oczapowskiego 7, 10-719 Olsztyn

Bibliografia

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  • 7.Brown M. S., Goldstein J. L.: The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 1997, 89, 331-340.
  • 8.Cella N., Groner B., Hynes N. E.: Characterization of Stat5a and Stat5b homodimers and heterodimers and their association with the glucocorticoid receptor in mammary cells. Mol. Cell. Biol. 1998, 18, 1783-1792.
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  • 11.Ghosal D., Shappell, Keenan T. W.: Endoplasmic reticulum lumenal proteins of rat mammary gland. Potential involvement in lipid droplet assembly during lactation. Biochim. Biophys. Acta 1994, 1200, 175-181.
  • 12.Gouilleux F., Wakao H., Mundt V., Groner B.: Prolactin induces phosphorylation of Tyr694 of STAT5 (MFG), a prerequisite for DNA binding and induction of transcription. EMBO J. 1994, 13, 4361-4369.
  • 13.Heid H. W., Keenan T. W.: Intracellular origin and secretion of milk fat globules. Eur. J. Cell Biol. 2005, 84, 245-258.
  • 14.Horton J. D., Goldstein J. L., Brown M. S.: SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J. Clin. Invest. 2002, 109, 1125-1131.
  • 15.Keenan T. W.: Milk lipid globules and their surrounding membrane: A brief history and perspectives for future research. J. Mammary Gland Biol. Neoplasia 2001, 6, 365-371.
  • 16.Koletzko B., Rodriguez-Palermo M., Demmelmair H., Fidler N., Jensen R., Sauerwald T.: Physiological aspects of human milk lipids. Early Hum. Dev. 65 Suppl., 2001, 3-18.
  • 17.Lebrun J. J., Ali S., Sofer L., Ullrich A., Kelly P. A.: Prolactin-induced proliferation of Nb2 cells involves tyrosine phosphorylation of the prolactin receptor and its associated tyrosine kinase JAK2. J. Biol. Chem. 1994, 269, 14021-14026.
  • 18.Lemay D. G., Neville M. C., Rudolph M. C., Pollard K. S., German J. B.: Gene regulatory networks in lactation: identification of global principles using bioinformatics. BMC Syst. Biol. 2007, 1, 56.
  • 19.Lollivier V., Guinard-Flament J., Ollivier-Bousquet M., Marnet P. G.: Oxytocin and milk removal: to important sources of variation in milk production and milk quality during and between milking. Reprod. Nutr. Dev. 2002, 42, 173-186.
  • 20.Mather I. H., Keenan T. W.: Origin and secretion of milk lipids. J. Mammary Gland Biol. Neoplasia 1998, 3, 259-273.
  • 21.McArthur M. J., Atshaves B. P., Frolov A., Foxworth W. D., Kier A. B., Schroeder F.: Cellular uptake and intracellular trafficking of long chain fatty acids. J. Lipid Res. 1999, 40, 1371-1383.
  • 22.McManaman J. L., Russell T. D., Schaack J., Orlicky D. J., Robenek H.: Molecular determinants of milk lipid secretion. J. Mammary Gland Biol. Neoplasia 2007, 12, 259-268.
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  • 26.Rudolph M. C., McManaman J. L., Phang T., Russell T., Kominsky D. J., Serkova N. J., Stein T., Anderson S. M., Neville M. C.: Metabolic regulation in the lactating mammary gland: a lipid synthesizing machine. Physiol. Genomics 2007, 28, 323-336.
  • 27.Sinha Y. N.: Structural variants of prolactin: occurence and physiological significance. Endocr. Rev. 1995, 16, 354-369.
  • 28.Spitsberg V. L.: Bovine milk fat globule membrane as a potential nutraceutical. J. Dairy Sci. 2005, 88, 2289-2294.
  • 29.Sundqvist A., Goechea-Alonso M. T., Ye X., Lukiyanchuk V., Jin J., Harper J. W., Ericsson J.: Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCFFbw7. Cell Metab. 2005, 1, 379-391.
  • 30.Uchide T., Onda K., Bonkobara M., Thongsong B., Matsuki N., Inaba M., Ono K.: Utilization of intestinal trigliceride-rich lipoproteins in mammary gland of cows. J. Vet. Med. Sci. 1999, 61, 1143-1146.
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Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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