Benefits of sea buckthorn juice consumption in women of productive age with hypercholesterolemia

• Autorzy: Kopcekova J. , Mrazova J. , Fatrcova-Sramkova K. , Habanova M. , Gazarova M. , Lenartova P.
• Języki publikacji: EN

Abstrakty

EN

Background. Sea buckthorn contains almost 200 nutrients and bioactive substances, including phenolic compounds such as flavonoids, vitamins, proteins, amino acids, minerals, alkaloids, chlorophyll derivatives, amines, organic acids, fatty acids and phytosterols. Human and animal studies suggest that sea buckthorn may have a variety of beneficial effects: cardioprotective, antiatherogenic, antioxidant, anticancer, immunomodulatory, antibacterial, antiviral and antiinflammatory. Objective. The aim of this study was to evaluate the effect of regular consumption of 100% sea buckthorn juice on the risk factors of cardiovascular diseases in women of productive age with hypercholesterolemia. Material and Methods. A clinical study involved 19 women with a mean age of 54.06 ±2.97 years who consumed 50 mL of sea buckthorn juice daily for 8 weeks. Anthropometric and biochemical parameters in blood serum were monitored before the start of sea buckthorn consumption and after 8 weeks of consumption. Body composition was determined using an multifrequency analyzer InBody720. Routine biochemical analyzes were performed by standard methods in an accredited laboratory of the University Hospital by automatic biochemical analyzer BioMajesty JCA-BM6010/C. Statistical comparison between individual measurements was performed using a paired t-test, using Statistica Cz version 10 (TIBCO Software, Inc., Palo Alto, CA, USA). Results. We observed significant decrease of body weight, body mass index (P<0.05), body fat and visceral fat (P<0.001) after 8 weeks of consumption of 100% sea buckthorn juice. In this intervention study, we observed a significant decrease in low-density cholesterol (P˂0.05) and a significant increase in high-density cholesterol (P˂0.001). The level of triglycerides was similar at the end of the study (P>0.05). After the intervention, we observed decrease of orosomucoid, immunoglobulin A, immunoglobulin G, immunoglobulin M (P<0.001) and C-reactive protein (P<0.01). Conclusions. The obtained results support the hypothesis that the daily consumption of sea buckthorn juice for eight weeks could contribute to the beneficial effects of reducing the risk of cardiovascular diseases, such as the reduction of body and visceral fat, LDL-C, CRP and the increase of HDL-C.

• Wydawca: -
• Czasopismo: Roczniki Państwowego Zakładu Higieny
• Rocznik: 2023
• Tom: 74
• Numer: 2
• Opis fizyczny: p.187-193,ref.

Twórcy

autor

Kopcekova J.

• Institute of Nutrition and Genomics, Faculty of Agrobiology and Food Resources, Slovak University of Agriculture in Nitra, Nitra, Slovak Republic

autor

Mrazova J.

• Institute of Nutrition and Genomics, Faculty of Agrobiology and Food Resources, Slovak University of Agriculture in Nitra, Tr.A.Hlinku 2, 949 76 Nitra, Slovak Republic

autor

Fatrcova-Sramkova K.

• Institute of Nutrition and Genomics, Faculty of Agrobiology and Food Resources, Slovak University of Agriculture in Nitra, Nitra, Slovak Republic

autor

Habanova M.

• Institute of Nutrition and Genomics, Faculty of Agrobiology and Food Resources, Slovak University of Agriculture in Nitra, Nitra, Slovak Republic

autor

Gazarova M.

• Institute of Nutrition and Genomics, Faculty of Agrobiology and Food Resources, Slovak University of Agriculture in Nitra, Nitra, Slovak Republic

autor

Lenartova P.

• Institute of Nutrition and Genomics, Faculty of Agrobiology and Food Resources, Slovak University of Agriculture in Nitra, Nitra, Slovak Republic

Bibliografia

• 1. Babiarczyk B., Turbiarz A.: Body Mass Index in elderly people – the reference ranges matter? Progress in Health Sciences 2012;2(1):58-67.
• 2. Bekker N.P., Glushenkowa A.I.: Components of certain species of Elaeagnaceae family. Chem Nat Compd 2001;37:97-116.
• 3. Bhardwaj R.L., Nandal U., Pal A., Jain S.: Bioactive compounds and medicinal properties of fruit juices. Fruits 2014;69:391-412 doi:10.1051/fruits/2014027.
• 4. Chandra S., Zafar R., Dwivedi P., Shinde L.P., Prita B.: Pharmacological and nutritional importance of sea buckthorn (Hippophae). The Pharma Innovation Journal 2018;7(5):258-263.
• 5. Chong M.F.F., Macdonald R., Lovegrove J.A.: Fruit polyphenols and CDV risk: a review of human intervention studies. Br J Nutr 2010;104:S28eS39 doi:10.1017/s0007114510003922.
• 6. Christaki E.: Hippophae rhamnoides L. (Sea buckthorn): a potential source of nutraceuticals. Food Pub Health 2012;2:69-72 doi:10.5923/j.fph.20120203.02.
• 7. Ciesarová Z., Murkovic M., Cejpek K., Kreps F., Tobolková B., Koplík R., Belajová E., Kukurová K., Daško Ľ., Panovská Z., Revenco D., Burčová Z.: Why is sea buckthorn (Hippophae rhamnoides L.) so exceptional? A review. Food Res Int 2020;133: 109170 doi:10.1016/j.foodres.2020.109170.
• 8. Dallmeier D., Larson M.G., Vasan R.S., Keaney J.F., Fontes J.D., Meigs J.B. et al.: Metabolic syndrome and inflammatory biomarkers: a community-based cross-sectional study at the Framingham Heart Study. Diabetology and metabolic syndrome 2012;4(1):28.
• 9. Del Pinto R., Ferri C.: Inflammation-Accelerated Senescence and the Cardiovascular System: Mechanisms and Perspectives. Int J Mol Sci 2018;19:3701 doi:10.3390/ijms19123701.
• 10. Drossard C., Fröhling B., Bolzenius K., Dietrich H., Kunz C., Kersting M.: Liking of anthocyanin-rich juices by children and adolescents. Appetite 2012;58(2):623-628 doi:10.1016/j.appet.2012.01.002.
• 11. Eccleston C., Baoru Y., Tahvonen R., Kallio H., Rimbach G.H., Minihane A.M.: Effects of an antioxidant-rich juice (sea buckthorn) on risk factors for coronary heart disease in humans. J Nutr Biochem 2002;13(6):346-354 doi:10.1016/s0955-2863(02)00179-1.
• 12. Eilat-Adar S., Goldbourt U.: Nutritional Recommendations for Preventing Coronary Heart Disease in Women: Evidence Concerning Whole Foods and Supplements. Nutr Metab Cardiovasc Dis 2010;20:459-466 doi:10.1016/j.numecd.2010.01.011.
• 13. Feigin V.L., Krishnamurthi R.V., Parmar P., Norrving B., Mensah G.A., Bennett D.A. et al.: Update on the global burden of ischemic and hemorrhagic stroke in 1990-2013: the GBD 2013 study. Neuroepidemiology 2015;45(3):161-176 doi:10.1159/000441085.
• 14. Gao X., Ohlander M., Jeppsson N., Bjork L., Trajkovski V.: Changes in antioxidant effects and their relationship to phytonutrients in fruits of Sea buckthorn (Hippophae rhamnoides L.) during maturation. J Agric Food Chem 2001;48:1485-1490.
• 15. Hemler E.C., Hu F.B.: Plant-Based Diets for Personal, Population, and Planetary Health. Adv Nutr 2019;10:S275-S283 doi:10.1093/advances/nmy117.
• 16. Huang R.Y, Huang C.C., Hu F.B., Chavarro J.E.: Vegetarian diets and weight reduction: a meta-analysis of randomized controlled trials. J Gen Intern Med 2016;31(1):109-116 doi: 10.1007/s11606-015-3390-7.
• 17. Jaśniewska A., Diowksz A.: Wide Spectrum of Active Compounds in Sea Buckthorn (Hippophae rhamnoides) for Disease Prevention and Food Production. Bioavailability and Bioactivity of Plant Antioxidants 2021;10(8):1279 doi:10.3390/antiox10081279.
• 18. Ji M., Gong X., Li X., Wang C., Li M.: Advanced Research on the Antioxidant Activity and Mechanism of Polyphenols from Hippophae Species – A Review. Molecules 2020;25(4):917 doi:10.3390/molecules25040917.
• 19. Kashyap Pyiush P. et al.: Antioxidants in Fruits: Properties and Health Benefits. Singapore, Springer Nature Singapore Pte Ltd. 637, 2020. ISBN 978-981-15-7285-2.
• 20. Kumar R., Kumar G.P., Chaurasia O.P., Singh S.: Phytochemical and pharmacological profile of Seabuckthorn oil: a review. Res J Med Plant 2011;5:491-499 doi:10.3923/rjmp.2011.491.499.
• 21. Larmo P.S., Yang B., Hurme S.A., Alin J.A., Kallio H.P., Salminen E.K., Tahvonen R.L.: Effect of a low dose of sea buckthorn berries on circulating concentrations of cholesterol, triacylglycerols, and flavonols in healthy adults. Eur J Nutr 2009;48:277-282 doi:10.1007/s00394-009-0011-4.
• 22. Lehtonen H.M., Suomela J.P., Tahvonen R., Yang B., Venojärvi M., Viikari J., Kallio H.: Different berries and berry fractions have various but slightly positive effects on the associated variables of metabolic diseases on overweight and obese women. Eur J Clin Nutr 2011;65(3):394-401 doi: 10.1038/ejcn.2010.268.
• 23. Loo B.M., Erlund I., Koli R., Puukka P., Hellström J., Wähälä K., Mattila P., Jula A.: Consumption of chokeberry (Aronia mitschurinii) products modestly lowered blood pressure and reduced low-grade inflammation in patients with mildly elevated blood pressure. Nutr Res 2016;36(11):1222-1230 doi: 10.1016/j. nutres.2016.09.005.
• 24. Malinowska P., Olas B.: Sea buckthorn-valuable plant for health. Kosmos 2016;65(2):285-292.
• 25. Middleton E.J., Kandaswami C., Theoharides T.C.: The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacol Rev 2000;52:673-751.
• 26. Mushtaq M., Wani S.M.: Polyphenols and human health – A review. International Journal of Pharma and BioSciences 2013;4:338-360.
• 27. Nazir A., Wani S., Gani A., Masoodi F.A., Haq E., Mir S.A., Riyaz U.: Nutritional, antioxidant and antiproliferative properties of persimmon (Diospyros kaki) – a minor fruit of J&K India. International Journal of Advanced Research 2013;1:545-554.
• 28. Nijveldt R.J., Van Nood E., Van Hoorn D.E., Boelens P.G., Van Norren K., Van Leeuwen P.A.: Flavonoids: a review of probable mechanisms of action and potential applications. Am J Clin Nutr 2001;74:418-425. doi:10.1093/ajcn/74.4.418.
• 29. Nuttall F.Q.: Body Mass Index: Obesity, BMI, and Health: A Critical Review. Nutr. Today 2015;50:117-128 doi:10.1097/nt.0000000000000092.
• 30. O’Morain V.L., Ramji D.P.: The Potential of Probiotics in the Prevention and Treatment of Atherosclerosis. Mol Nutr Food Res 2020;64:e1900797.
• 31. Pan L., Yang Z., Wu Y., Yin R.X., Liao Y., Wang J. et al.: The prevalence, awareness, treatment and control of dyslipidemia among adults in China. Atherosclerosis 2016;248:2-9 doi:10.1016/j.atherosclerosis.2016.02.006.
• 32. Patel C.A., Divakar K., Santani D., Solanki H.K., Thakkar J.H.: Remedial Prospective of Hippophae rhamnoides Linn. (Sea Buckthorn). ISRN Pharmacol 2012;1-6 doi: 10.5402/2012/436857.
• 33. Peluso I., Villano D.V., Roberts S.A., Cesqui E., Raguzzini A., Borges G., Crozier A., Catasta G., Toti E., Serafini M.: Consumption of mixed fruit-juice drink and vitamin C reduces postprandial stress induced by a high fat meal in healthy overweight subjects. Curr Pharm Des 2014;20(6):1020-1024 doi:10.2174/13816128 2006140220144802.
• 34. Prabhu S.D., Frangogiannis N.G.: The Biological Basis for Cardiac Repair After Myocardial Infarction: From Inflammation to Fibrosis. Circ Res 2016;119:91-112 doi:10.1161/circresaha.116.303577.
• 35. Pundir S., Garg P., Dviwedi A. et al.: Ethnomedicinal uses, phytochemistry and dermatological effects of Hippophae rhamnoides L. J. Ethnopharmacology 2021;266:113434 doi:10.1016/j.jep.2020.113434.
• 36. Rein D., Schijlen E., Kooistra T., Herbers K., Verschuren L., Hall R., Sonnewald U., Bovy A., Kleemann R.: Transgenic flavonoid tomato intake reduces C-reactive protein in human C-reactive protein transgenic mice more than wild-type tomato. J Nutr 2006;136:2331- 2337 doi:10.1093/jn/136.9.2331.
• 37. Rodríguez-García C., Sánchez-Quesada C., Toledo E., Delgado-Rodríguez M., Gaforio J.J.: Naturally Lignan-Rich Foods: A Dietary Tool for Health Promotion? Molecules 2019;24:917 doi: 10.3390/molecules24050917.
• 38. Rodriguez-Roque M.J., Rojas-Grau M.A., Elez-Martinez P., Martin-Belloso O.: In vitro bioaccessibility of healthrelated compounds as affected by the formulation of fruit juice- and milk-based beverages. Food Res. Int. 2014;62:771-778 doi:10.1016/j.foodres.2014.04.037.
• 39. Ruparelia N., Choudhury R.: Inflammation and atherosclerosis: what is on the horizon? Heart 2020;106:80-85 doi:10.1136/heartjnl-2018-314230.
• 40. Sacchetti G., Maietti S., Muzzoli M., Scaglianti M., Manfredini S., Radice M., Bruni R.: Comparative evaluation of 11 essential oils of different origin as functional antioxidants, antiradicals and antimicrobials in foods. Food Chem 2005;91(4):621-632 doi:10.1016/j.foodchem.2004.06.031.
• 41. Sadef Y., Javed T., Javed R., Mahmood A., Alwahibi M.S., Elshikh M.S., AbdelGawwa M.R., Alhaji J.H., Rasheed R.A.: Nutritional status, antioxidant activity and total phenolic content of different fruits and vegetables’ peels. PLoS One 2022;17:e0265566. doi: 10.1371/journal.pone.0265566.
• 42. Sikora J., Broncel M., Markowicz M., Chałubiński M., Wojdan K., Mikiciuk-Olasik E.: Short-term supplementation with Aronia melanocarpa extract improves platelet aggregation, clotting, and fibrinolysis in patients with metabolic syndrome. Eur J Nutr 2012;51(5):549-556 doi:10.1007/s00394-011-0238-8.
• 43. Singh G.M., Micha R., Khatibzadeh S., Shi P., Lim S., Andrews K.G., Engell R.E., Ezzati M., Mozaffarian D.: Correction: Global, Regional, and National Consumption of Sugar-Sweetened Beverages, Fruit Juices, and Milk: A Systematic Assessment of Beverage Intake in 187 Countries. PLoS One 2019;14(3):e0214344 doi:10.1371/journal.pone.0214344.
• 44. Stanaway J.D., Afshin A., Gakidou E., Lim S.S., Abate D., Abate K.H., Abbafati C., Abbasi N., Abbastabar H., Abd-Allah F. et al.: Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990–2017: A systematic analysis for the global burden of disease study 2017. Lancet 2018;392:1923-1994.
• 45. Starek M., Guja A., Dabrowska M., Krzek J.: Assay of β-carotene in dietary supplements and fruit juices by TLC-densitometry. Food Anal Methods 2015;8(5):1347-1355 doi:10.1007/s12161-014-0019-0.
• 46. Teleszko M., Wojdyło A., Rudzińska M., Oszmiański J., Golis T.: Analysis of Lipophilic and Hydrophilic Bioactive Compounds Content in Sea Buckthorn (Hippophae rhamnoides L.) Berries. J Agric Food Chem 2015;63(16):4120-4129 doi:10.1021/acs.jafc.5b00564.
• 47. Tripathy J.P., Thakur J.S., Jeet G., Chawla S., Jain S., Pal A. et al.: Burden and risk factors of dyslipidemiaresults from a STEPS survey in Punjab India. Diabetes Metab Syndr 2017;11(Supp.1):S21-S27 doi:10.1016/j. dsx.2016.08.015.
• 48. Turner-McGrievy G., Mandes T., Crimarco A.: A plantbased diet for overweight and obesity prevention and treatment. J Geriatr Cardiol 2017;14(5):369-374 doi:10.11909/j.issn.1671-5411.2017.05.002.
• 49. Vilas-Franquesa A., Saldo J., Juan B.: Potential of sea buckthorn-based ingredients for the food and feed industry – a review. Food Prod Process and Nutr 2020;2(1) doi:10.1186/s43014-020-00032-y.
• 50. Wal A., Wal P., Roohi T.F.: A review on role of berries and its bioactive compounds in treating hypertension. Asian Journal of Pharmaceutical and Clinical Research 2020;13(8):3-12 doi:10.22159/ajpcr.2020.v13i8.37932.
• 51. Wang Z., Zhao F., Wei P., Chai X., Hou G., Meng Q. 2022. Phytochemistry, health benefits, and food applications of sea buckthorn (Hippophae rhamnoides L.): A comprehensive review. Frontiers in Nutrition 2022;9:1-20 doi:10.3389/fnut.2022.1036295.
• 52. Wannamethee S.G., Lowe G.D., Rumley A., Bruckdorfer K.R., Whincup P.H.: Associations of vitamin C status, fruit and vegetable intakes, and markers of inflammation and hemostasis. Am J Clin Nutr 2006;83:567-574 doi: 10.1093/ajcn.83.3.567.
• 53. Wu H., Li Ch., Cui M., Guo H., Chen S. et al.: Polyphenols from Hippophae rhamnoides suppressed colon cancer growth by regulating miRNA-mediated cell cycle arrest and apoptosis in vitro and in vivo. Journal of Functional Foods 2021;87:104780 doi:10.1016/j.jff.2021.104780.
• 54. Xing J., Yang B., Dong Y., Wang B., Wang J., Kallio H.P.: Effects of sea buckthorn (Hippophae rhamnoides L.) seed and pulp oils on experimental models of gastric ulcer in rats. Fitoterapia 2002;73(7-8):644-650 doi:10.1016/s0367-326x(02)00221-6.
• 55. Yang B., Kallio H.: Supercritical Co-extracted sea buckthorn (Hippophae rhamnoides) oils as new food ingredients for cardiovascular health. Proc Health Ingred 2002;17(19):7.
• 56. Yu E., Malik V.S., Hu F.B.: Cardiovascular Disease Prevention by Diet Modification: JACC Health Promotion Series. J Am Coll Cardiol 2018;72(8):914-926 doi:10.1016/j.jacc.2018.02.085.
• 57. Yusuf S., Joseph P., Rangarajan S., Islam S., Mente A., Hystad P., Brauer M., Kutty V.R., Gupta R., Wielgosz A. et al.: Modifiable risk factors, cardiovascular disease, and mortality in 155 722 individuals from 21 high-income, middle-income, and low-income countries (PURE): A prospective cohort study. Lancet 2020;395:795-808 doi:10.1016/s0140-6736(19)32008-2.
• 58. Zaha D., Vesa C., Uivarosan D., Bratu O., Fratila O., Mirela Tit D., Pantis C., Diaconu C., Bungau S.: Influence of inflammation and adipocyte biochemical markers on the components of metabolic syndrome. Exp Ther Med 2020;20:121-128 doi:10.3892/etm.2020.8663.
• 59. Zeb A.: Chemical and nutritional constituents of sea buckthorn juice. Pak J Nutr 2004;3:99-106 doi:10.3923/pjn.2004.99.106.

Identyfikatory

DOI

10.32394/rpzh.2023.0258