Responses of Nili-Ravi buffalo to aflatoxin B1 with and without toxin adsorbents

• Autorzy: Akhtar R. , Sardar M. , Saima N. , Saleem G. , Imran S. , Aslam A.
• Języki publikacji: EN

Abstrakty

EN

The objective of the study was to determine the responses of Nili-Ravi buffalo to aflatoxin B1 (AFB1) in terms of feed intake, haematological and serum biochemical parameters and to compare the efficacy of three different toxin adsorbents against AFB1. Twenty-five Nili-Ravi buffaloes were selected from a herd and were divided into five groups for a period of 21 days to receive: no aflatoxin B1 (AFB1) in the diet, a diet contaminated with AFB1, a diet contaminated with AFB1 with the addition of one of three different toxin adsorbents: glucomannan, hydrated sodium calcium aluminosilicate (HSCAS), or activated charcoal at an inclusion level of 0.2% of feed. AFB1 was incorporated into feed at an inclusion level of 500 µg · kg–1 per animal per day. The results indicate that the average daily feed intake of AFB1-treated buffaloes significantly declined (P < 0.05) compared with the control. Serum levels of total bilirubin, alkaline phosphatase (ALP), alanine aminotransferase (ALT), aspartate aminotransferase (AST) and creatinine were significantly increased (P < 0.05) in response to AFB1, but the change in blood urea nitrogen (BUN) levels was nonsignificant (P > 0.05). In haematology, the total erythrocyte count (TEC), total leukocyte count (TLC), haemoglobin concentration (HGB), haematocrit levels (HCT), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC) decreased significantly (P < 0.05) in the AFB1 group on days 14 and 21 of the experiment. From among the three toxin adsorbents, 0.2% glucomannan significantly (P < 0.05) improved the feed intake levels of buffaloes and also significantly (P < 0.05) minimized the AFB1-induced adverse effects on haematology and serum biochemistry, but was unable to totally ameliorate its effect, while HSCAS was less effective, and activated charcoal, the least.

• Wydawca: -
• Czasopismo: Journal of Animal and Feed Sciences
• Rocznik: 2014
• Tom: 23
• Numer: 4
• Opis fizyczny: p.317-323,fig.,ref.

Twórcy

autor

Akhtar R.

• Department of Pathology, Faculty Veterinary Sciences, University of Veterinary and Animal Sciences, Sheikh Abdul Qadir Jilani Road, 54000 Lahore, Pakistan

autor

Sardar M.

• Department of Pathology, Faculty Veterinary Sciences, University of Veterinary and Animal Sciences, Sheikh Abdul Qadir Jilani Road, 54000 Lahore, Pakistan

autor

Saima N.

• Department of Animal Nutrition, University of Veterinary and Animal Sciences, Sheikh Abdul Qadir Jilani Road, 54000 Lahore, Pakistan

autor

Saleem G.

• Department of Pathology, Faculty Veterinary Sciences, University of Veterinary and Animal Sciences, Sheikh Abdul Qadir Jilani Road, 54000 Lahore, Pakistan

autor

Imran S.

• Department of Surgery, University of Veterinary and Animal Sciences, Sheikh Abdul Qadir Jilani Road, 54000 Lahore, Pakistan

autor

Aslam A.

• Department of Pathology, Faculty Veterinary Sciences, University of Veterinary and Animal Sciences, Sheikh Abdul Qadir Jilani Road, 54000 Lahore, Pakistan

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