Protective effectiveness of anise against testicular ischemia and reperfusion injury: An experimental study in rats

• Autorzy: Yildizhan E. , Akkus M. , B.V. Ulger , Asır F. , Soker S , Gunduz E. , Rencber M. , Barcin M.
• Języki publikacji: EN

Abstrakty

EN

Testicular torsion is a frequently encountered clinical condition that requires urgent treatment. The aim of this study is to investigate the efficacy of Anise (Pimpinella anisum L.) in treating the pathological condition due to ischemia and reperfusion injury by using biochemical, histopathological and immunohistochemical methods. A total of 6 groups were formed with 8 male Wistar Albino rats in each group. Group 1 (n=8): control group, Group 2 (n=8): Anise aqueous solution was given orally 5 ml/kg by gavage for 30 days. Group 3 (n=8): Ischemia and Reperfusion (I/R) group, bilateral testicles were rotated 270° and reperfused after 30 minutes of ischemia. Group 4 (n=8): I/R+ Anise group, Group 5 (n=8): Anise+ I/R group and Group 6 (n=8): Anise+ I/R+ Anise group. The results of the Anise group and the Control group were similar. However, the damage in the I/R group was considerably more severe than in any of the other study groups. While it was observed that spermatogenic cells started to regenerate in the I/R+Anise group, edema and congestion were observed in the Anise+I/R group. In the Anise+I/R+Anise group, all histological findings and biochemical parameters were similar to those of the control group. It was observed that anise had protective effects in ischemia and reperfusion injury in rat testicles.

• Wydawca: -
• Czasopismo: Polish Journal of Veterinary Sciences
• Rocznik: 2023
• Tom: 26
• Numer: 2
• Opis fizyczny: p.249–255,fig.,ref.

Twórcy

autor

Yildizhan E.

• Dicle University, Faculty of Medicine, Department of Histology and Embryology, Kıtılbıl Mah. 21280, Diyarbakır, Turkey

autor

Akkus M.

• Dicle University, Faculty of Medicine, Department of Histology and Embryology, Kıtılbıl Mah. 21280, Diyarbakır, Turkey

autor

B.V. Ulger

• Dicle University, Faculty of Medicine, Department of General Surgery, Kıtılbıl Mah. 21280, Diyarbakır, Turkey

autor

Asır F.

• Dicle University, Faculty of Medicine, Department of Histology and Embryology, Kıtılbıl Mah. 21280, Diyarbakır, Turke

autor

Soker S

• Dicle University, Faculty of Medicine, Department of Histology and Embryology, Kıtılbıl Mah. 21280, Diyarbakır, Turkey

autor

Gunduz E.

• Dicle University, Faculty of Medicine, Department of Emergency Medicine, Kıtılbıl Mah. 21280, Diyarbakır, Turkey

autor

Rencber M.

• Department of General Surgery, Viransehir State Hospital, Ceylanpınar Yolu No:3, 63700 Viranşehir/Şanlıurfa, Turkey

autor

Barcin M.

• Dicle University, Faculty of Medicine, Department of General Surgery, Kıtılbıl Mah. 21280, Diyarbakır, Turkey

Identyfikatory

DOI

10.24425/pjvs.2023.145029