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Czasopismo

2014 | 59 | 1 |

Tytuł artykułu

Toxocariasis and lung function: Relevance of a neglected infection in an urban landscape

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Toxocariasis has been highlighted as a potentially important neglected infection of poverty in developed countries that experience substantive health disparities such as the United States. An association between Toxocara infection and lung function, in concert with a relatively high prevalence of infection, may mark an important mechanism by which this infection could contribute significantly to the differential morbidity across different socioeconomic groups and landscapes. To assess the potential relevance of this infection in a dense urban environment, we measured the association between forced expiratory volume in 1 second (FEV1) and serology diagnosed Toxocara infection in a sample of US-born New York City residents. We identified a significant independent association between Toxocara infection and lung function, wherein those with previous Toxocara infection had a 236.9 mL reduced FEV1 compared to those without Toxocara infection even after adjusting for age, sex, ethnicity, level of education, smoking status, body mass index, and pet ownership. These findings from New York City corroborate similar findings in a national sample and, while the cross-sectional data preclude a direct causal relationship, this study identifies a potentially important neglected infection in a dense urban landscape.

Wydawca

-

Czasopismo

Rocznik

Tom

59

Numer

1

Opis fizyczny

p.126-131,fig.,ref.

Twórcy

autor
  • Department of Epidemiology and Biostatistics, School of Public Health, State University of New York, Downstate, Brooklyn, NY, USA
autor
  • Departments of Cell Biology, Pathology and Medicine, College of Medicine, State University of New York, Downstate, Brooklyn, NY, USA

Bibliografia

  • Adler N.E. and Rehkopf D.H. 2008. U.S. disparities in health: descriptions, causes, and mechanisms. Annual Review of Public Health, 29, 235–252.
  • Buijs J., Borsboom G., van Gemund J.J., Hazebroek A., van Dongen P.A., van Knapen F., Neijens H.J. 1994. Toxocara seroprevalence in 5-year-old elementary schoolchildren: relation with allergic asthma. American Journal Epidemiology, 140, 839–847
  • Buijs J., Egbers M.W., Lokhorst W.H., Savelkoul H.F., Nijkamp F.P. 1995. Toxocara-induced eosinophilic inflammation. Airway function and effect of anti-IL-5. American Journal of Respiratory and Critical Care Medicine, 151(3 Pt 1), 873–878.
  • Buijs J., Borsboom G., Renting M., Hilgersom W.J., van Wieringen J.C., Jansen G., Neijens J. 1997. Relationship between allergic manifestations and Toxocara seropositivity: a cross-sectional study among elementary school children. European Respiratory Journal, 10, 1467–1475.
  • Centers for Disease Control and Prevention. (2007). Documentation, codebook and frequencies; surplus sera laboratory component: antibody to Toxocara larva migrans. NHANES III, series 11 Data Files 26A. Available via http://www.cdc.gov/nchs/about/major/nhanes/archive_whatsnew.htm.
  • Chan P.W., Anuar A.K., Fong M.Y., Debruyne J.A., Ibrahim J. 2001. Toxocara seroprevalence and childhood asthma among malaysian children. Pediatrics International, 43, 350–353
  • Congdon P. and Lloyd P. 2011. Toxocara infection in the United States: the relevance of poverty, geography and demography as risk factors, and implications for estimating county prevalence. International Journal of Public Health, 56, 15–24.
  • Feldman G.J. and Parker H.W. 1992. Visceral larva migrans associated with the hypereosinophilic syndrome and the onset of severe asthma. Annals of Internal Medicine, 116, 838–840.
  • Hankinson J.L. and Bang K.M. 1991. Acceptability and reproducibility criteria of the American Thoracic Society as observed in a sample of the general population. American Review of Respiratory Disease, 143, 516–521.
  • Hotez P.J. 2008. Neglected infections of poverty in the United States of America. PloS Neglected Tropical Diseases, 2, e256.
  • Hotez P.J. and Wilkins P.P. 2009. Toxocariasis: America’s most common neglected infection of poverty and a helminthiasis of global importance? PLoS Neglected Tropical Diseases, 3, e400.
  • Kuk S., Ozel E., Oğuztürk H., Kirkil G., Kaplan M. 2006. Seroprevalence of Toxocara antibodies in patients with adult asthma. Southern Medical Journal, 99, 719–722.
  • National Center for Health Statistics, U.S. Department of Health and Human Services (DHHS). Third National Health and Nutrition Examination Survey, 1988–1994, NHANES III Examination Data File (CD-ROM). Public Use Data File Documentation Number 76200. Hyattsville, MD.: Centers for Disease Control and Prevention, 1996. Available from National Technical Information Service (NTIS), Springfield, VA. Acrobat.PDF format; includes access software: Adobe Systems, Inc. Acrobat Reader 2.1.
  • Oteifa N.M., Moustafa M.A. and Elgozamy B.M. 1998. Toxocariasis as a possible cause of allergic diseases in children. Journal of the Egyptian Society of Parasitology, 28, 365–372.
  • Pinelli E., Withagen C., Fonville M., Verlaan A., Dormans J., van Loveren H., Nicoll G., Maizels R.M., van der Giessen J. 2005. Persistent airway hyper-responsiveness and inflammation in Toxocara canis-infected BALB/c mice. Clinical and Experimental Allergy, 35, 826–32.
  • Pritchard D.I., Eady R.P., Harper S.T., Jackson D.M., Orr T.S.C., Richards I.M., Trigg S., Wells E. 1983. Laboratory infection of primates with Ascaris suum to provide a model of allergic bronchoconstriction. Clinical and Experimental Immunology, 54, 469–476.
  • Sharghi N., Schantz P.M., Caramico L., Ballas K., Teague B.A., Hotez P.J. 2001. Environmental exposure to Toxocara as a possible risk factor for asthma: a clinic-based case-control study. Clinical Infectious Diseases, 32, E111–116.
  • Walsh M.G. 2011. Toxocara infection and diminished lung function in a nationally representative sample from the United States population. International Journal for Parasitology, 41, 243–247.
  • Weiss S.T. 2000. Parasites and asthma/allergy: What is the relationship? Journal of Allergy and Clinical Immunology, 105(2 Pt 1), 205–10.
  • Won K.Y., Kruszon-Moran D., Schantz P.M., Jones J.L. 2008. National seroprevalence and Risk Factors for Zoonotic Toxocara spp. Infection. American Journal of Tropical Medicine and Hygiene, 79, 552–557.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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