Ketogenic diet and sexual motivation in male rats

• Autorzy: Bogacki-Rychlik W. , Bialy M. , Grajoszek A. , Przybyla M. , Slugocka A. , Barski J.J.
• Języki publikacji: EN

Abstrakty

EN

INTRODUCTION: The ketogenic diet (KD) is a very‑low‑carbohydrate, high‑fat and adequate protein nutritional approach that induces metabolic shift to the use of ketone bodies instead of glucose as a main energy source. For decades, the KD has been employed to manage drug-resistant epilepsy, but recently it is increasingly considered as an alternative or add-on therapy in many other disorders. The positive effect of the KD on social behavior has been recently reported in rodent models of autism spectrum disorder (ASD) and wild type early adult male rats. AIM(S): Given, however, the influence of ketone bodies on many humoral parameters including testosterone, we decided to look closer at the sexual interactions of male rats subjected to the KD. METHOD(S): In our study, we examined behavior of males in response to female presence with concomitant analysis of ultrasonic vocalizations (USV) during sexual interactions. RESULTS: Percent of males starting to copulation significantly decreased during the second sexual session, which suggests lower sexual motivation in male rats on the KD. FINANCIAL SUPPORT: Funding: Ministry of Science and Higher Education, grant number KNW‑1‑053/N/8/I.

• Wydawca: -
• Czasopismo: Acta Neurobiologiae Experimentalis
• Rocznik: 2019
• Tom: 79
• Numer: Suppl.1
• Opis fizyczny: p.LIII

Twórcy

autor

Bogacki-Rychlik W.

• Laboratory of Centre for Preclinical Research, Department of Experimental and Clinical Physiology, Medical University of Warsaw, Warsaw, Poland

autor

Bialy M.

• Laboratory of Centre for Preclinical Research, Department of Experimental and Clinical Physiology, Medical University of Warsaw, Warsaw, Poland

autor

Grajoszek A.

• Department for Experimental Medicine, Medical University of Silesia in Katowice, Katowice, Poland
• Department of Physiology, School of Medicine in Katowice, Medical University of Silesia in Katowice, Katowice, Poland

autor

Przybyla M.

• Department for Experimental Medicine, Medical University of Silesia in Katowice, Katowice, Poland
• Department of Physiology, School of Medicine in Katowice, Medical University of Silesia in Katowice, Katowice, Poland

autor

Slugocka A.

• Department for Experimental Medicine, Medical University of Silesia in Katowice, Katowice, Poland
• Department of Physiology, School of Medicine in Katowice, Medical University of Silesia in Katowice, Katowice, Poland

autor

Barski J.J.

• Department for Experimental Medicine, Medical University of Silesia in Katowice, Katowice, Poland
• Department of Physiology, School of Medicine in Katowice, Medical University of Silesia in Katowice, Katowice, Poland