Basic morphofunctional features of pharmaceutic leech (Hirudo verbana Carena, 1820) tissues in various forms of response after hirudotherapeutic procedures

• Autorzy: Frolov A. K. , Litvinenko R. A.
• Języki publikacji: EN

Abstrakty

EN

It is analyzed morphofunctional features of Hirudo verbana tissues on histological sections in order to determine the possible causes of their partial death after hirudotherapeutic procedure. In the study was taken 4 groups of leeches: hungry (control), healthy well-fed, well-fed that vomited blood and well-fed dead. Morphofunctional changes in midgut of healthy well-fed H. verbana compared to the hungry are the changes of epithelium height through stretching eaten blood. In well-fed that vomited blood and well-fed dead leeches in the intestinal epithelium were observed degenerative processes that are accompanied by a decrease in the height of the epithelium, its partial desquamation. Botryoidal tissue of hungry leeches is in an inactive state, in healthy well-fed ones it responds with an increased physiological vascularization, activation of some botryoidal granulocytes with an increase in their average size, on receipt of the products of digestion. Activation of some botryoidal granulocytes, without a significant increase in their sizes, in well-fed leeches that vomited eaten blood and well-fed dead leeches, with increased infiltration of the adjacent connective tissue lymphocyte- and macrophage-like cells, amebocytes and granulocytes indicates the development of pathological processes, which are resulting in immunological conflict between eaten human blood and leeches’ tissue microenvironment.

• Wydawca: -
• Czasopismo: Annals of Parasitology
• Rocznik: 2015
• Tom: 61
• Numer: 1
• Opis fizyczny: p.27-35,fig.,ref.

Twórcy

autor

Frolov A. K.

• Faculty of Biology, Zaporizhzhia National University, Zhukovskogo 66, 69600 Zhaporizhzhia, Ukraine

autor

Litvinenko R. A.

• Faculty of Biology, Zaporizhzhia National University, Zhukovskogo 66, 69600 Zhaporizhzhia, Ukraine

Bibliografia

• [1] Abdullah S., Dar L.M., Rashid A., Tewari A. 2012. Hirudotherapy/leech therapy: applications and indications in surgery. Archives of Clinical and Experimental Surgery 1: 172-180.
• [2] Sobczak N., Kantyka M. 2014. Hirudotherapy in veterinary medicine. Annals of Parasitology 60: 89- 92.
• [3] Kamenev O.Ju., Baranovskij A.Ju. 2006. Treatment by leeches: theory and practice of hirudotherapy: a guide for physicians. IG «Ves’», St. Petersburg (In Russian).
• [4] Savinov V.A. (Ed.). 2004. Hirudotherapy: guide. Medicina, Moscow (In Russian).
• [5] Frolov O.K., Kopijka V.V., Fedotov Je.R., Litvinenko R.O. 2011. Trophic properties ecotypes medicinal leeches in natural reservoirs and in biotechnology. Visnyk of Zaporizhzhya National University. Biological Sciences 1: 117-122 (In Ukrainian).
• [6] Rassadina E.V. 2006. Environmentally sound biotechnological reproduction of Hirudo medicinalis L. under laboratory conditions. Thesis for PhD (Biology): 03.00.23, 03.00.16. Ulyanovsk (In Russian).
• [7] Dul‘nev G.N., Krashenjuk A.I. 2010. From the synergetics to the informational medicine. Institute of Biosensory Psychology, St. Petersburg (In Russian).
• [8] Tkachev V.O., Gojman E.V., Lykov A.P., Kudaeva O.T., Kolesnikova O.P. 2006. Indicators of hematopoiesis in the dynamics of development of chronic graft versus host disease. Immunologiya 27: 168-170 (In Russian).
• [9] Gojman E.V. 2011. Homeostatic proliferation in the development of autoimmune pathology induced by chronic reaction „graft versus host”. Thesis abstract for PhD (Medicine): 14.03.09. Novosibirsk (In Russian).
• [10] Romejs B. 1953. Microscopic technique: monograph. (Ed. I.I. Sokolova). Izd-vo inostr. lit., Moscow (In Russian).
• [11] de Eguileor M., Grimaldi A., Tettamanti G., Congiu T., Protasoni M., Reguzzoni M., Valvassori R., Lanzavecchia G. 2001. Ultrastructure and functional versatility of hirudinean botryoidal tissue. Tissue and Cell 33: 332-341.
• [12] Tettamanti G., Grimaldi A., Rinaldi L., Arnaboldi F., Congiu T., Valvassori R., de Eguileor M. 2004. The multifunctional role of fibroblasts during wound healing in Hirudo medicinalis (Annelida, Hirudinea). Biology of the Cell 96: 443-455.
• [13] Grimaldi A., Ferrarese R., Tettamanti G., Valvassori R., de Eguileor M. 2013. Ras activation in Hirudo medicinalis angiogenic process. Invertebrate Survival Journal 10: 7-14.
• [14] Kutschera U., Roth M. 2005. Cannibalism in a population of the medicinal leech (Hirudo medicinalis L.). Biology Bulletin 32: 626-628.
• [15] Ceylan M., Erbatur I. 2012. A study on nutrition of medicinal leech (Hirudo verbana Carena, 1820): Cannibalism? Ege Journal of Fisheries and Aquatic Sciences 29: 167-170.
• [16] Ivanov A.V., Monchadskij A.S, Poljanskij Ju. I., Strelkov A.A. 1983. Large workshop in Invertebrate Zoology: handbook. 3th edition. Part 2: Types: Annelida, Arthropoda. Vysshaia shkola, Moscow (In Russian).
• [17] Rahemo Z.I.F., Hamad N.R. 2013. Histology of the body wall of the piscine leech, Cystibranchus mastacembeli (Hirudinea: Piscicolidae). Journal of Agricultural Science and Technology 3: 136-143.
• [18] de Eguileor M., Grimaldi A., Tettamanti G., Valvassori R., Cooper E. L., Lanzavecchia G. 2000. Different types of response to foreign antigens by leech leukocytes. Tissue and Cell 32: 40-48.
• [19] Bradbury S. 1959. The botryoidal and vaso-fibrous tissue of the leech Hirudo medicinalis. Quarterly Journal of Microscopical Science s3-100: 483-498.
• [20] Vetvicka V., Sima P. 2009. Origins and functions of annelide immune cells: the concise survey. Invertebrate Survival Journal 6: 138-143.
• [21] Drannik G.N., Drannik A.G. 2011. Clinical immunology and allergology: guide for students, medical interns, immunologists, allergists, medical therapeutic profile of all spec. Responsible for the release V.P. Pshenichnyj. 5th edition. Poligrafpljus, Kiev (In Russian).
• [22] Ivashkina V.T., Lapina T.L. (Eds.). 2012. Gastro - enterology. National manual: short edition. GJeOTAR-Media, Moscow (In Russian).
• [23] Ovsyannikova V.V., Kozlova I.V. 2010. Clinicodiagnostic value of functional morphological changes of intestine in encephalopathy development in cirrhosis. Saratov Journal of Medical Scientific Research 6: 365-369 (In Russian).
• [24] Moes N.D., Ruemmele F.M., Rings E.H. 2011. Autoimmune enteropathy in children. Nederlands Tijdschrift voor Geneeskunde 155: 32-46.