Host response to the presence of Helicobacter spp. DNA in the liver of patients with chronic liver diseases

• Autorzy: Rybicka M. , Nakonieczna J. , Stalke P. , Bielawski K. P.
• Języki publikacji: EN

Abstrakty

EN

Literature data indicate an association between the presence of Helicobacter spp. in the liver and the development of hepatocellular carcinoma (HCC). However, the role of H. pylori infections in chronic liver diseases (CLD) remains controversial. The aim of this study was to detect Helicobacter spp. DNA in patients with CLD, and to investigate the host response to the presence of the bacterium in the liver. Helicobacter spp. DNA was detected in 59% samples. H.pylori was the most prevalent species (94%). We estimated the expression level of IL-1 and IL-8 genes. The presence of Helicobacter spp. did not have a significant effect on the gene expression of IL-8 and IL-1.

Słowa kluczowe

EN

host response; Helicobacter; DNA; liver; patient; chronic liver disease; human disease; interleukin 1; interleukin 8

• Wydawca: -
• Czasopismo: Polish Journal of Microbiology
• Rocznik: 2011
• Tom: 60
• Numer: 2
• Opis fizyczny: p.175-178,ref.

Twórcy

autor

Rybicka M.

• Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, Gdansk, Poland

autor

Nakonieczna J.

autor

Stalke P.

autor

Bielawski K. P.

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