The study of canine atopic dermatitis involving the isolation of dogs

• Autorzy: Fujimura M.
• Języki publikacji: EN

Abstrakty

EN

Twenty-seven pruritic dogs were used in this study. When a hypoallergenic diet was fed to these 27 dogs for six weeks, none of the dogs showed improvement of the pruritus. These dogs had a history and clinical signs of atopic dermatitis (AD) as defined by Prelaud’s diagnostic criteria. Subsequently, the 27 dogs were isolated for observation for two weeks in the hospital. In the isolation room in the veterinary clinic, cages and tableware were all stainless steel, and carpet was not used. A hypoallergenic diet was continuously fed to the 27 dogs for two weeks, during which time they were kept in the isolation room. PVAS (Pruritus Visual Analog Scale) was performed prior to starting the isolation, at the start of the study and 2 weeks after starting the isolation. In 17dogs (63%) the pruritus improved in the isolation room. A statistically significant reduction (p<0.01) of PLS (Pruritus liners score) was recorded 2 weeks after isolation. It was hypothesized that the 17 dogs whose pruritus improved in the isolation room had AD caused by an environmental antigen that was not present in the isolation room. Pruritus of the remaining 10 dogs (37%) did not improve. For 6/10 dogs, the intradermal allergy testing was positive for an environmental antigen. For4/10 dogs, the intradermal allergy testing was negative for all environmental antigens. Dogs for which sensitivity to an environmental antigen was not identified were thought to have atopic-like dermatitis.

Słowa kluczowe

EN

dog; animal disease; atopic dermatitis; dermatitis; isolation; atopic-like dermatitis

• Wydawca: -
• Czasopismo: Polish Journal of Veterinary Sciences
• Rocznik: 2011
• Tom: 14
• Numer: 2
• Opis fizyczny: p.273-277, fig.,ref.

Twórcy

autor

Fujimura M.

• Fujimura Animal Allergy Hospital, 5-10-26 Aomatanihigashi, Minou-city, Osaka, 562-0022, Japan

Bibliografia

• Brenninkmeijer EE, Spuls PI, Legierse CM, Lindeboom R, Smitt JH, Bos JD (2008) Clinical differences atopic and atopiform dermatitis. J Am Acad Dermatol 58: 407-414.
• Chua YY, Bremner K, Lakdawalla N, Llobet JL, Kokubu HL, Orange RP, Collins-Williams C (1987) In vivo and in vitro correlates of food allergy. J Allergy Clin Immunol 58: 299-307.
• DeBoer DJ, Hillier A (2001) The ACVD task force on canine atopic dermatitis (XV): fundamental concept in clinical diagnosis. Vet Immunol Immunopathol 81: 271-276.
• Goldstein GB, Heiner DC (1970) Clinical and immunological perspectives in food sensitivity. A review. J Allergy 46: 270-291.
• Griffin CE, DeBoer DJ (2001) The ACVD task force on canine atopic dermatitis (XIV): clinical manifestations of canine atopic dermatitis. Vet Immunol Immunopathol 81: 255-269.
• Halliwell R (2006) Revised nomenclature for veterinary allergy. Vet Immunol Immunopathol 114: 207-208.
• Halpern GM, Scott JR (1987) Non-IgE antibody mediated mechanisms in food Allergy. Ann Allergy 58: 14-27.
• Hillier A, Griffin CE (2001) The ACVD task force on canine atopic dermatitis (X): is there a relationship between cannine atopic dermatitis and cutaneous adverse food reactions?. Vet Immunol and Immunopathol 81: 227-231.
• Ishida R, Masuda K, Kurata K, Ohno K,Tsujimoto H (2004) Lymphocyte blastogenic responses to inciting food allergens in dogs with food hypersensitivity. J Vet Intern Med 18: 25-30.
• Nesbitt GH (1978) Canine allergic inhalant dermatitis: a review of 230 cases. J AmVet Med Assoc 172: 55-60.
• Nuttall TJ, Thoday KL, van den Broek AH, Jackson HA, Sture GH, Halliwell RE (1998) Retrospective survey of allergen immunotherapy in canine atopy. Vet Rec 143: 139-142.
• Olivry T, Rivierre C, Jackson HA, Murphy KM, Davidson G, Sousa CA (2002) Cyclosporine decreases skin lesions and pruritus in dogs with atopic dermatitis: a blinded randomized prednisolone-controlled trial. Vet Dermatol 13: 77-87.
• Saevik BK, Thoresen SI, Kristensen F (2002) A retrospective study of hyposensitization in canine atopy based on a polyclonal ELISA test. Vet Res Commun 26: 613-624.
• White SD (1986) Food hypersensitivity in 30 dogs. J Am Vet Med Assoc 188: 695-698.
• Willemse A, Van den Brom WE, Rijnberk A (1984) Effect of hyposensitization on atopic dermatitis in dogs. J Am Vet Med Assoc 184: 1277-1280.
• Zur G, White SD, Ihrke PJ, Kass PH, Toebe N (2002) Canine atopic dermatitis: a retrospective study of 169 cases examined at the University of California, Davis, 1992-1998, Part II, Response to hyposensitization. Vet Dermatol 13: 103-11.