Wpływ toksykozy zearalenonowej na wyniki badania morfologicznego i biochemicznego krwi dzików

• Autorzy: Nicpon J. , Slawuta P. , Nicpon J.

Warianty tytułu

EN

Effect of zearalenone toxicosis on the complete blood cell count and serum biochemical analysis in wild boars

• Języki publikacji: PL

Abstrakty

EN

The aim of this study was to assess the effect of zearalenones (ZEA) on the complete blood cell count and serum chemistry analysis in wild boars (Sus scrofa). At the beginning of the study, blood was collected from 24 wild boars. The following parameters were evaluated: the leukocyte and red blood cell counts, haemoglobin concentration, MCV, MCH, MCHC, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, urea, creatinine, total protein, albumin, total bilirubin, calcium, inorganic phosphorus and magnesium. The wild boars were then divided into three study groups containing six sows and two boars each. The study was carried out over the course of three years. Group I received feed for fattening boars and corn containing 50 µg of ZEA. Group II received the same feed as group I, with the addition of a pure form of ZEA, supplemented at a dose of 150 µg/kg/day for 7 days every 2 months. In the course of the study, the animals in this group received a total of nine 7-day administrations of this toxin. Group III was the control group. A complete blood cell count and serum biochemical analysis were performed once again at the end of the study, and, in group I, three months after commencing the study. The CBC indices measured at the end of the study did not differ significantly among the three groups. There were significant differences in the AST, ALT and total bilirubin concentrations measured at the end of the study between group I and the remaining two groups. The high AST, ALT and total bilirubin concentrations suggest that a three-year-long ingestion of mouldy feed significantly affects the liver function, but does not cause clinical signs of poisoning.

Słowa kluczowe

PL

dziki; zatrucia; mikotoksyny; zearalenon; oddzialywanie na organizm; badania krwi; wskazniki biochemiczne; wskazniki morfologiczne

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2016
• Tom: 72
• Numer: 04
• Opis fizyczny: s.250-254,tab.,bibliogr.

Twórcy

autor

Nicpon J.

• Centrum Diagnostyki Eksperymentalnej i Innowacyjnych Technologii Biomedycznych, Uniwersytet Przyrodniczy we Wrocławiu, pl.Grunwaldzki 47, 50-366 Wrocław

autor

Slawuta P.

• Katedra Chorób Wewnętrznych z Kliniką Koni, Psów i Kotów, Wydział Medycyny Weterynaryjnej, Uniwersytet Przyrodniczy we Wrocławiu, pl.Grunwaldzki 47, 50-366 Wrocław

autor

Nicpon J.

• Katedra i Klinika Chirurgii, Wydział Medycyny Weterynaryjnej, Uniwersytet Przyrodniczy we Wrocławiu, pl.Grunwaldzki 51, 50-366 Wrocław

Bibliografia

• Barasona J. A., López-Olvera J. R., Beltrán-Beck B., Gortázar C., Vicente J.: Trap-effectiveness and response to tiletamine-zolazepam and medetomidine anaesthesia in Eurasian wild boar captured with cage and corral traps. Vet. Res. 2013, 23, 107-117.
• Berg T.: How to establish international limits for mycotoxins in food and feed? Food Control 2003, 14, 219-224.
• Binder E. M.: Managing the risk of mycotoxins in modern feed production. Anim. Feed Sci. Tech. 2007, 133, 149-166.
• Bouhet S., Oswald I. P.: The effects of mycotoxins, fungal food contaminants, on the intestinal epithelial cell-derived innate immune response. Vet. Immunol. Immunopathol. 2005, 108, 199-209.
• Casas-Díaz E., Closa-Sebastià F., Marco I., Lavín S., Bach-Raich E., Cuenca R.: Hematologic and biochemical reference intervals for Wild Boar (Sus scrofa) captured by cage trap. Vet. Clin. Pathol. 2015, 20, 1-8.
• Christensen C. M., Nelson G. H., Mirocha C. J.: Effect on the white rat uterus of a toxic substance isolated from Fusarium. Appl. Microbiol. 1965, 13, 653-659.
• Diekman M. A., Green M. L.: Mycotoxins and reproduction in domestic livestock. J. Anim. Sci. 1992, 70, 1615-1627.
• Egmond H. P. van, Schothorst R. C., Jonker M. A.: Regulations relating to mycotoxins in food perspectives in a global and European context. Anal. Bioanal. Chem. 2007, 389, 147-157.
• Eppley R. M., Stoloff L., Trucksess M. W., Chung C. W.: Survey of corn for Fusarium toxins.: J. Assoc. Off. Anal. Chem. 1974, 57, 632-635.
• Fels-Klerx H. J. van der, Kandhai M. C., Brynestad S., Dreyer M., Börjesson T., Martins H. M., Uiterwijk M., Morrison E., Booij C. J. H.: Development of a European system for identification of emerging mycotoxins in wheat supply chains. World Mycotoxin J. 2009, 2, 109-112.
• Gajęcka M., Jakimiuk E., Zielonka Ł., Obremski K., Gajęcki M.: The biotransformation of chosen the mycotoxins. Pol. J. Vet. Sci. 2009, 12, 293-303.
• Gajęcki M.: Wchłanianie mikotoksyn u zwierząt, [w:] Posyniak A., Szkoda J. (red.): Leki weterynaryjne i zanieczyszczenia środowiskowe w żywności i paszach – aspekty analityczne i ochrona zdrowia publicznego. Państwowy Instytut Weterynaryjny – Państwowy Instytut Badawczy w Puławach, Puławy 2009, s. 91.
• Gajęcki M.: Zearalenone – undesirable substances in feed. Pol. J. Vet. Sci. 2002, 5, 117-122.
• Gajęcki M., Gajęcka M., Jakimiuk E., Zielonka Ł., Obremski K.: Zearalenone – undesirable substance. Mahendra Rai, Ajit Varma (ed.): Mycotoxins in Food, Feed and Bioweapons. Springer-Verlag, Berlin, Heidelberg 2010, s. 131.
• Gajęcki M., Przybyłowicz M., Obremski K., Zielonka Ł., Zwierzchowski W., Skorska-Wyszyńska E., Gajęcka M., Polak M., Jakimiuk E.: Preliminary results of monitoring research on zearalenone presence in blood of women with neoplastic lesions in reproductive system. Pol. J. Vet. Sci. 2004, 7, 153-156.
• Hussein H. S., Brasel J. M.: Toxicity, metabolism, and impact of mycotoxins on humans and animals. Toxicology 2001, 167, 101-134.
• Juszkiewicz T., Piskorska-Pliszczyńska J.: Occurrence of mycotoxins in animal feeds. J. Environ. Pathol. Toxicol. Oncol. 1992, 11, 211-215.
• López-Olvera J. R., Höfle U., Vicente J., Fernández-de-Mera I. G., Gortázar C.: Effects of parasitic helminths and ivermectin treatment on clinical parameters in the European wild boar (Sus scrofa) Parasitol. Res. 2006, 98, 582-587.
• Obremski K., Zalewski K., Gajęcka M., Giżejewski Z., Zielonka Ł., Gajęcki M., Nitkiewicz B.: Zearalenone intoxication of game animals. Pol. J. Natur. Sci. 2006, 21, 1099-1106.
• Price K. R., Fenwick G. R.: Naturally occurring oestrogens in foods – a review. Food Addit. Contam. 1985, 2, 73-106.
• Richard J. L.: Some major mycotoxins and their mycotoxicoses – An overview. Int. J. Food Microbiol. 2007, 119, 3-10.
• Tiemann U., Tomek W., Schneider F., Vanselow J.: Effects of the mycotoxins alpha- and beta-zearalenol on regulation of progesterone synthesis in cultured granulosa cells from porcine ovaries. Reprod. Toxicol. 2003, 17, 673-681.
• Tiemann U., Viergutz T., Jonas L., Schneider F.: Influence of the mycotoxins alpha- and beta-zearalenol and deoxynivalenol on the cell cycle of cultured porcine endometrial cells. Reprod. Toxicol. 2003, 17, 209-221.