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2012 | 59 | 3 |
Tytuł artykułu

NF-kappaB signaling pathway and free radical impact

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Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
 The activation of NF-κB transcription factor is critical for a wide range of processes such as immunity, inflammation, cell development, growth and survival. It is activated by a variety of stimuli including cytokines, ionizing radiation and oxidative stress. Redox modulations of NF-κB pathway have been widely demonstrated. Studies carried out during last years have advanced our knowledge about possible connections between NF-κB pathway and the impact of free radicals. This review is an endeavor to gather recent results focused on this issue, although an important question, whether oxidative stress plays a physiological role in NF-κB activation, seems to be still unanswered.
Wydawca
-
Rocznik
Tom
59
Numer
3
Opis fizyczny
p.323-331,fig.,ref.
Twórcy
autor
  • Nicolaus Copernicus University, Department of Clinical Biochemistry, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland
Bibliografia
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