Molecular basis of dendritic arborization

• Autorzy: Urbanska M. , Blazejczyk M. , Jaworski J.
• Języki publikacji: EN

Abstrakty

EN

The pattern of dendritic branching along with the receptor and channel composition and density of synapses regulate the electrical properties of neurons. Abnormalities in dendritic tree development lead to serious dysfunction of neuronal circuits and, consequently, the whole nervous system. Not surprisingly, the complicated and multi-step process of dendritic arbor development is highly regulated and controlled at every stage by both extrinsic signals and intrinsic molecular mechanisms. In this review, we analyze the molecular mechanisms that contribute to cellular processes that are crucial for the proper formation and stability of dendritic arbors, in such distant organisms as insects (e.g. Drosophila melanogaster), amphibians (Xenopus laevis), and mammals.

• Wydawca: -
• Czasopismo: Acta Neurobiologiae Experimentalis
• Rocznik: 2008
• Tom: 68
• Numer: 2
• Opis fizyczny: p.264-288,fig.,ref.

Twórcy

autor

Urbanska M.

• International Institute of Molecular and Cell Biology, Warsaw, Poland
• Warsaw University of Life Sciences, Warsaw, Poland

autor

Blazejczyk M.

• International Institute of Molecular and Cell Biology, Warsaw, Poland
• Laboratory of Molecular Neurobiology, Nencki Institute, Warsaw, Poland

autor

Jaworski J.

• International Institute of Molecular and Cell Biology, Warsaw, Poland

Uwagi

PL

Rekord w opracowaniu