Toksykogenomika w ocenie zagrożeń substancji chemicznych

• Autorzy: Kostka G. , Liszewska M. , Urbanek-Olejnik K.

Warianty tytułu

EN

Toxicogenomics in hazard assessment of chemicals

• Języki publikacji: PL

Abstrakty

PL

Zmiany jakie dokonały się w ostatnich latach w Europejskiej legislacji substancji chemicznych wskazują na pilną potrzebę wprowadzania nowych, alternatywnych metod badania substancji chemicznych. Możliwości takie stwarza toksykogenomika, dziedzina nauki łącząca wiedzę z zakresu toksykologii, nauki zajmującej się badaniem właściwości czynników toksycznych i negatywnymi skutkami ich oddziaływania na zdrowie i środowisko z genomiką, nauką o budowie i funkcjonowaniu genomów. Nowe strategie badawcze w toksykologii (transkryptomika, proteomika, metabolomika) stwarzają warunki do oceny zagrożeń związanych z oddziaływaniem substancji chemicznych zarówno o uznanym potencjale toksycznym jak również tych, które mogą posiadać taki potencjał.

EN

Recent changes in the European legislation of chemicals suggest an urgent need for introduction of novel, alternative methods for testing chemical substances. Such possibility is offered by toxicogenomics – a scientific discipline combining knowledge from the field of toxicology, i.e. a science investigating the properties of toxic agents and the negative effects these agents exert on health and environment, with genomics, i.e. a science investigating the structure and function of genomes. New research strategies within the field of toxicology (transcriptomics, proteomics, metabolomics) offer conditions to assess the hazards associated with the effects of chemicals with both established and suspected toxic potentials.

• Wydawca: -
• Czasopismo: Roczniki Państwowego Zakładu Higieny
• Rocznik: 2010
• Tom: 61
• Numer: 2
• Opis fizyczny: s.119-127,rys.,bibliogr.

Twórcy

autor

Kostka G.

• Zakład Toksykologii Środowiskowej, Narodowy Instytut Zdrowia Publicznego – Państwowy Zakład Higieny w Warszawie, ul.Chocimska 24, 00-791 Warszawa

autor

Liszewska M.

autor

Urbanek-Olejnik K.

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