Galanin - immunoreactive nerve fibers in the mucosal layer of the canine gastrointestinal tract during inflammatory bowel disease

• Autorzy: Rychlik A. , Gonkowski S. , Nowicki M. , Calka J. , Szweda M.
• Języki publikacji: EN

Abstrakty

EN

The effect of inflammatory bowel disease (IBD) on the density of galanin - immunoreactive (GAL-IR) nerve fibers was determined in the mucosa of canine duodenum, jejunum, and descending colon. Fiber densitx was evaluated by a single immunofluorescence method in biopsy specimens obtained from healthy dogs and patients with variable severity of the disease. The densit) of GAL-IR nerve fibers was determined by the semi-quantitative method by counting fibers in the field of view (0.1 mm²). Fiber density was higher in dogs with moderate and severe IBD than in healthy animals. The results of the study suggest that GAL present in intestinal nerve fibers could play a role in the pathogenesis and development of canine IBD.

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2015
• Tom: 59
• Numer: 1
• Opis fizyczny: p.143-148,fig.,ref.

Twórcy

autor

Rychlik A.

• Department of Clinical Diagnostics, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-957 Olsztyn, Poland

autor

Gonkowski S.

• Department of Clinical Physiology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-957 Olsztyn, Poland

autor

Nowicki M.

• Department of Clinical Diagnostics, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-957 Olsztyn, Poland

autor

Calka J.

• Department of Clinical Physiology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-957 Olsztyn, Poland

autor

Szweda M.

• Department of Clinical Diagnostics, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-957 Olsztyn, Poland

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Identyfikatory

DOI

10.1515/bvip-2015-0021