EN
The histopathological examination can be supplemented by immunohisto(cyto)chemical examination, cytometry or molecular techniques, making it possible to determine the statistical probability of metastasis. This assists in the selection of appropriate individual treatment that can be the most effective and have the fewest side effects in a given patient. The study describes the basics of neoplastic treatment, including multidrug resistance (MDR). It characterizes the role of transporters (molecular pumps, e.g. ABC – ATP-binding cassettes, RND, SMR, MFS and P450 – CYP), complications of neoplastic therapy (e.g. myelosuppression, acute tumor lysis syndrome), and minimal residual disease (MRD).