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2016 | 19 | 2 |
Tytuł artykułu

Influence of various carbohydrate sources on postprandial glucose, insulin and NEFA concentrations in obese cats

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Carbohydrate is an important source of energy, which can significantly affect postprandial blood glucose and insulin levels in cats. In healthy animals, this is not a big concern; however, in obese and diabetic animals, this is an important detail. In the present study, the impact of four different carbohydrate sources (glucose, maltose, corn starch, and trehalose) on short-term post-prandial serum glucose, insulin, and non-esterified fatty acid (NEFA) concentrations was investigated with four obese cats. Each of the carbohydrate sources was added to a commercial wet food diet for feeding the animals. A significant difference was observed in postprandial glucose, insulin, and NEFA area under the curve (AUC) values between each carbohydrate source in obese cats. Furthermore, glucose and maltose induced the highest postprandial glucose and insulin AUC values, whereas trehalose induced the lowest postprandial glucose and insulin AUC value amongst all carbohydrate sources, respectively, in obese cats. However, trehalose has a higher risk of inducing side effects, such as diarrhea, as compared to other carbohydrate sources. As such, different carbohydrate sources appear to have a very significant impact on post-prandial glycemia and subsequent insulin requirement levels in obese cats. These results might be useful when selecting a prescription diet for obese or diabetic cats. In addition, maltose appears to be capable of inducing experimentally evoked postprandial hyperglycemia in obese cats, which may serve as a good tool for use to check the impact and effectiveness of newly developed oral hypoglycemic drugs or supplements for cats in future experiments.
Słowa kluczowe
EN
Wydawca
-
Rocznik
Tom
19
Numer
2
Opis fizyczny
p.387-391,fig.,ref.
Twórcy
autor
  • School of Veterinary Nursing and Technology, Faculty of Veterinary Science, Nippon Veterinary and Life Science University, 1-7-1 Kyonancho, Musashino, Tokyo 180-8602, Japan
autor
  • School of Veterinary Nursing and Technology, Faculty of Veterinary Science, Nippon Veterinary and Life Science University, 1-7-1 Kyonancho, Musashino, Tokyo 180-8602, Japan
autor
  • School of Veterinary Medicine, Faculty of Veterinary Science, Nippon Veterinary and Life Science University, 1-7-1 Kyonancho, Musashino, Tokyo 180-8602, Japan
autor
  • School of Veterinary Nursing and Technology, Faculty of Veterinary Science, Nippon Veterinary and Life Science University, 1-7-1 Kyonancho, Musashino, Tokyo 180-8602, Japan
autor
  • School of Veterinary Nursing and Technology, Faculty of Veterinary Science, Nippon Veterinary and Life Science University, 1-7-1 Kyonancho, Musashino, Tokyo 180-8602, Japan
autor
  • School of Veterinary Nursing and Technology, Faculty of Veterinary Science, Nippon Veterinary and Life Science University, 1-7-1 Kyonancho, Musashino, Tokyo 180-8602, Japan
Bibliografia
  • Coradini M, Rand JS, Morton JM, Rawlings JM (2011) Effects of two commercially available feline diets on glucose and insulin concentrations, insulin sensitivity and energetic efficiency of weight gain. Br J Nutr 106 (Suppl 1): 64-77.
  • Cowey CB, Knox D, Walton MJ, Adron JW (1977) The regulation of gluconeogenesis by diet and insulin in rainbow trout (Salmo gairdneri). Br J Nutr 38: 463-470.
  • de-Oliveira LD, Carciofi AC, Oliveira MC, Vasconcellos RS, Bazolli RS, Pereira GT, Prada F (2008) Effects of six carbohydrate sources on diet digestibility and postprandial glucose and insulin responses in cats. J Anim Sci 86: 2237-2246.
  • Galand G (1989) Brush border membrane sucrase-isomaltase, maltase-glucoamylase and trehalase in mammals. Comparative development, effects of glucocorticoids, molecular mechanisms, and phylogenetic implications. Comp Biochem Physiol B 94: 1-11.
  • Hietanen E (1973) Interspecific variation in the levels of intestinal alkaline phosphatase, adenosine triphosphatase and disaccharidases. Comp Biochem Physiol A 46: 359-369.
  • Hore P, Messer M (1968) Studies on disaccharidase activities of the small intestine of the domestic cat and other carnivorous mammals. Comp Biochem Physiol 24: 717-725.
  • Maki KC, Kanter M, Rains TM, Hess SP, Geohas, J (2009) Acute effects of low insulinemic sweeteners on postprandial insulin and glucose concentrations in obese men. Int J Food Sci Nutr 60 (Suppl 3): 48-55.
  • Martin LJ, Siliart B, Lutz TA, Biourge V, Nguyen P, Dumon HJ (2010) Postprandial response of plasma insulin, amylin and acylated ghrelin to various test meals in lean and obese cats. Br J Nutr 103: 1610-1619.
  • Nakaya M, Kito Y, Matsuki N, Shibata H, Touhata Y, Tamahara S, Ono K (2009) A novel sandwich enzyme-linked immunosorbent assay for feline insulin. J Vet Med Sci 71: 1005-1007.
  • Oku T, Nakamura S (2000) Estimation of intestinal trehalase activity from a laxative threshold of trehalose and lactulose on healthy female subjects. Eur J Clin Nutr 54: 783-788.
  • van Can JG, Ijzerman TH, van Loon LJ, Brouns F, Blaak EE (2009) Reduced glycaemic and insulinaemic responses following trehalose ingestion: implications for postprandial substrate use. Br J Nutr 102: 1395-1399.
  • Whelan W (2004) The wars of the carbohydrates: part 3: maltose. IUBMB Life 56: 641.
Typ dokumentu
Bibliografia
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Identyfikator YADDA
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