Effects of vitamin E, C, and a-lipoic acid supplementation on the serum glucose, lipid profile, and proteins in quails under heat stress

• Autorzy: Imik H. , Ozkanlar S. , Kaynar O. , Koc M.
• Języki publikacji: EN

Abstrakty

EN

The aim of this study was to determine the effects of vitamin E, C, and α-lipoic acid additions to the feed rations on the serum glucose, lipid profile, and proteins in Japanese quails (Coturnix coturnix japonica) under heat stress. The serum levels of phosphorus, calcium, and liver enzymes were also measured. All groups were kept under 34°C during the hours between 08⁰⁰ and 17⁰⁰ and the temperature was 24°C during the rest part of the day. The control group (BS) was fed a normal ration without having any supplement, while the other groups had a supplementation of vitamin E (BSE), vitamin C (BSC), vitamin E+C (BSEC), and lipoic acid (BSLA). The serum glucose level was found to be lower in BSE, BSC, and BSLA groups compared to the BS group (P<0.05). The triacylglycerol (TAG) percentage was the lowest in the BSEC group (P<0.05). The diacylglycerol (DAG) percentage in the BSEC and BSLA groups was lower than the other groups (P<0.001). The cholesterol percentage in BSC, BSEC, and BSLA was higher than in the BS group (P<0.001). The polarlipid percentage was highest in the BSEC group while the lowest ones were in the BS and BSE groups. The highest level of total protein was in the BSEC group (P<0.05). The levels of albumin in the BS, BSC and BSLA groups were significantly higher than in the BSE group (P<0.05). The highest level of globulin was detected in the BSEC group while the lowest one was in the BSE group (P<0.001). The level of phosphorus was significantly high in the BSLA group (P<0.05), and the level of calcium did not differ among the groups. The levels of liver enzymes in the groups fed additives tended to decrease without having any statistical significance. In conclusion, vitamin E decreased the glucose and globulin and increased the albumin; vitamin C decreased the glucose; vitamin E+C decreased the TAG and DAG and increased the protein and globulin; the lipoic acid increased the glucose, DAG, and phosphorus.

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2009
• Tom: 53
• Numer: 3
• Opis fizyczny: p.521-526,fig.,ref.

Twórcy

autor

Imik H.

• Department of Animal Nutrition and Nutritional Disorders, Faculty of Veterinary Sciences, Ataturk University, 25240 Erzurum, Turkey

autor

Ozkanlar S.

• Department of Biochemistry, Faculty of Veterinary Sciences, Ataturk University, 25240 Erzurum, Turkey

autor

Kaynar O.

• Department of Biochemistry, Faculty of Veterinary Sciences, Ataturk University, 25240 Erzurum, Turkey

autor

Koc M.

• Department of Biology, Faculty of Art and Sciences, Bozok University, 66200 Yozgat, Turkey

Bibliografia

• 1. Asrani R.K., Katoch R.C., Gupta V.K., Deshmukh S., Jindal N., Ledoux D.R., Rottinghaus G.E., Singh S.P.: Effect of feding Fusarium verticillioides (formerly Fusarium moiliforme) culture material containing known levels of Fumonisin B₁ in Japanese Quail (Coturnix coturnix japonica). Poult Sci 2006, 85, 1129-1135.
• 2. Azzi A., Stacker A.: Vitamin E: Non-antioxidant roles. Prog Lipid Res 2000, 39, 231-255.
• 3. Bernard F.: Handbook of Thin-Layer Chromatography, Lipids, Chapter 22, Edited by J. Sherma and B. Fried, Marcel Dekker, New York, 2003.
• 4. Bilska A., Włodek L.: Lipoic acid-the drug of the future? Pharmacol Rep 2005, 57, 570-577.
• 5. Bollengier-Lee S., Mitchell M.A., Utomo D.B., Williams P.E., Whitehead C.C.: Influence of high dietary vitamin E supplementation on egg production and plasma characteristics in hens subjected to heat stress. Br Poult Sci 1998, 39, 106-112.
• 6. Burtis C.A., Ashwood E.R., Bruns D.E.: Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. Elsevier Saunders, St. Louis, USA, 2006, p. 1085.
• 7. Chan K.M., Decker E.A.: Endogenous skeletal muscle antioxidants. Crit Rev Food Sci Nutr 1994, 34, 403-426.
• 8. Coates M.A.: The role of vitamins in metabolic processes. In: Physiology and Biochemistry of Domestic Fowl. Edited by D.J. Bell, B.M. Freeman, Academic Press, New York, 1971, pp. 373-396.
• 9. Donkoh A.: Ambient temperature: A factor affecting performance and physiological response of broiler chickens. Int J Biometeorol 1989, 33, 259-265.
• 10. Ensminger M.E., Oldfield J.E., Heinemann W.W.: Feeding. In: Feeds and Nutrition. Edited by W.W. Heinemann, Ensminger Publishing, California, 1990, pp. 108-110.
• 11. Felix T., Madison R., McDowell L.R., Wilkinson N.: Vitamins and minerals functioning as antioxidants with supplementation considerations. Florida Ruminant Nutrition Symposium. Best Western Gateway Grand. Gainesville, 2007. http://dairy.ifas.ufl.edu/files/rns/2007/McDowell.pdf.
• 12. Freeman B.A., Crapo J.D.: Biology of disease: Free radicals and tissue injury. Lab Invest 1982, 47, 412-426.
• 13. Hai L., Rong D., Zang Z.Y.: The effect of thermal environment on the digestion of broiler. J Anim Physiol Anim Nutr 2000, 83, 57-64.
• 14. Hamano Y.: Effects of dietary lipoic acid on plasma lipid, in vivo insulin sensitivity, metabolic response to corticosterone and in vitro lipolysis in broiler chickens. Br J Nutr 2006, 95, 1094-1101.
• 15. Hamano Y.: Influence of lipoic acid on lipid metabolism and β-adrenergic response to intravenous or oral administration of clenbuterol in broiler chickens. Reprod Nutr Dev 2002, 42, 307-316.
• 16. Hill J.A.: Indicators of stress in poultry. World's Poult Sci J 1983, 39, 24-32.
• 17. Keith R.L., Setiarahardjo I., Fernando Q., Aposhian H.V., Gandolfi A.J.: Utilization of renal slices to evaluate the efficacy of chelating agents for removing mercury from the kidneys. Toxicology 1997, 116, 67-75.
• 18. Larbier Z.M., Chagneau A.M., Geraert P.A.: Influence of ambient temperature on true digestibility of protein and amino acids of rapeseed and soybean meals in broilers. Poult Sci 1993, 72, 289-295.
• 19. Luadicina D.C., Marnett L.J.: Enhancement of hydroperoxide-dependent lipid peroxidation in rat liver microsomes by ascorbic acid. Arch Biochem Biophys 1990, 278, 73-80.
• 20. Madheswaran R., Balachandran C., Murali Manohar B.: Influence of dietary culture material containing aflatoxin and T₂ toxin on certain serum biochemical constituents in Japanese quail. Mycopathologia 2004, 158, 337-341.
• 21. Mahmoud K.Z., Edens F.W., Eise E.J., Havenstein G.B.: Ascorbic acid decreases heat shock protein 70 and plasma corticosterone response in broilers (Gallus gallus domesticus) subjected to cyclic heat stress. Comp Biochem Physiol B Biochem Mol Biol B 2004, 137, 35-42.
• 22. McDowell L.R.: Vitamins in animal nutrition. In: Comparative Aspects to Human Nutrition: Vitamin E. Edited by L.R. Mc Dowell: Academic Press, London, 1989, pp. 93-131.
• 23. Mckee J.S., Harrison P.C., Riskowski G.L.: Effect of supplemental ascorbic acid on the energy conversion of broiler chicks during heat stress and feed withdrawal. Poult Sci 1997, 76, 1278-1286.
• 24. Melnik B.C., Hollmann J., Erler E., Verhoeven B., Plewig G.: Microanalytical screening of all major stratum corneum lipids by sequential high-performance thin-layer chromatography. J Invest Dermatol 1989, 92, 231-234.
• 25. Muller L., Menzel H.: Studies on the efficacy of lipoate and dihydrolipoate in the alteration of cadmium toxicity in isolated hepatocytes. Biochim Biophys Acta 1990, 1052, 386-391.
• 26. National Research Council: Nutrient Requirements of Poultry. Edited by the National Academy Press, Washington, DC, 1994.
• 27. Oshima S., Ojima F., Sakamoto H., Ishiguro Y., Terao J.: Supplementation with carotenoids inhibit singlet oxygen mediated oxidation of human plasma low-density lipoprotein. J Agric Food Chem 1996, 44, 2306-2309.
• 28. Ou P., Tritschler H.J., Wolff S.P.: Thioctic (lipoic) acid: A therapeutic metal-chelating antioxidant? Biochem Pharmacol 1995, 50, 123-126.
• 29. Packer J.E., Slater T.F., Wilson R.L.: Direct observation of a free radical interaction between vitamin E and vitamin C. Nature 1979, 278, 737-738.
• 30. Pardue S.L., Thaxton J.P.: Ascorbic acid in poultry: A review. World Poult Sci J 1986, 42, 107-123.
• 31. Patel M.S., Vettakkorumakankav N.N.: Lipoic acid- requiring proteins: recent advances. In: Biothiols in Health and Disease. Editor Packer L., Cadenas E., Marcel Dekker Inc., New York, 1995, pp. 373-388.
• 32. Pritchard K.A.Jr., Patel S.T., Karpen C.W., Newman H.A., Panganamala R.V.: Triglyceride-lowering effect of dietary vitamin E in streptozocin-induced diabetic rats. Increased lipoprotein lipase activity in livers of diabetic rats fed high dietary vitamin E. Diabetes 1986, 35, 278-281.
• 33. Puthpongsiriporn U., Scheideler S.E., Sell J.L., Beck M.M.: Effects of vitamins E and C supplementation on performance, in vitro lymphocyte proliferation, and antioxidant status of laying hens during heat stress. Poult Sci 2001, 80, 1190-1200.
• 34. Sahin K., Kucuk O., Sahin N., Sari M.: Effects of vitamin C and vitamin E on lipid peroxidation status, some serum hormone, metabolite, and mineral concentrations of Japanese quails reared under heat stress (34°C). Int J Vit Nutr Res 2002, 72, 91-100.
• 35. Sahin K., Onderci M., Sahin N., Gursu M.F., Kucuk O.: Dietary vitamin C and folic acid supplementation ameliorates the detrimental effects of heat stress in Japanese quail. J Nutr 2003, 133, 1882-1886.
• 36. Sahin N., Sahin K., Onderci M., Sarkar F.H., Doerge D., Prasad A., Kücük O.: Effects of dietary genistein on nutrient use and mineral status in heat-stressed quails. Exp Anim 2006, 55, 75-82.
• 37. Schroeder F.: Role of membrane lipids asymmetry in aging. Neurobiol Aging 1984, 5, 323-326.
• 38. Seyrek K., Yenisey C., Serter M., Kargin Kiral F., Ulutas P.A., Bardakcioglu H.E.: Effects of dietary vitamin C supplementation on some serum biochemical parameters of laying Japanese quails exposed to heat stress (34.8°C). Revue Méd Vét 2004, 155, 339-342.
• 39. Siegel H.S.: Immunological responses as indicators of stress. World's Poult Sci J 1985, 41, 36-44.
• 40. Siegel H.S.: Stress, strains and resistance. Br Poult Sci 1995, 36, 3-22.
• 41. Sigel H., Prijs B., McCormick D.B., Shih J.C.H.: Stability of binary and ternary complexes of α-lipoate and lipoate derivatives with Mn²⁺, Cu²⁺, and Zn²⁺ in solution. Arch Biochem Biophys 1978, 187, 208-214.
• 42. Statistical Packages for the Social Sciences: SPSS for Windows release 10.01. SPSS Inc., Chicago, 1996.
• 43. Tanaka K., Hashimoto T., Tokumaru S., Iguchi H., Kojo S.: Interactions between vitamin C and vitamin E are observed in tissues of inherently scorbutic rats. J Nutr 1997, 127, 2060-2064.