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2015 | 22 | 3 |

Tytuł artykułu

Is there a relationship between inflammation and depression in athletes?

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Overtraining is a maladaptive state of athlete’s body related to the physical, behavioral and emotional condition, occurring when exercise training exceeds the recoverability. The cytokine hypothesis of overtraining promoted in recent years is seen as the prevailing theory explaining the understanding of the overtraining phenomenon. The high level of pro-inflammatory cytokines (IL-6, TNFα, IL-1β) involved in the inflammatory response may strongly influence not only the central nervous system but also the endocrine and immune systems. Moreover, there is a range of factors in athlete’s life that appear to increase the risk of depression development, such as psychological and emotional stress associated with sports competition. The aim of this review was to reveal the role of high level of proinflammatory cytokines observed in OTS with the possible occurrence of depression symptoms in athletes. Latest findings have shown an important role of the same pro-inflammatory cytokines in the development of depression. The study discusses a potential mechanism responsible for the development of depression in athletes, which may be helpful in the quick diagnosis of depression basis in athletes. Due to the low number of studies concerning depression and inflammation in athletes further research should be conducted.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

22

Numer

3

Opis fizyczny

p.113-123,fig.,ref.

Twórcy

  • Department of Physiological Science, University School of Physical Education, Poznan, Poland
autor
  • Department of Physiological Science, University School of Physical Education, Poznan, Poland
autor
  • Department of Human and Social Science, University School of Physical Education, Poznan, Poland

Bibliografia

  • 1. Piacentini MF, Meeusen R. An online training monitoring system to prevent non functional overreaching. Int J Sports Physiol Perform. 2014 DOI: 10.1123/ijspp.2014-0270.
  • 2. Smith AM. Injured athletes and the risk of suicide. J Athl Train. 1994; 29(4): 337-341.
  • 3. Puffer JC, McShane JM. Depression and chronic fatigue in athletes. Clin Sports Med. 1992; 11(2): 327-338.
  • 4. Smith LL. Cytokine hypothesis of overtraining: a physiological adaptation to excessive stress? Med Sci Sports Exerc. 2000; 32(2): 317-331.
  • 5. Carfagno DG, Hendrix JC 3rd. Overtraining syndrome in the athlete: current clinical practice. Curr Sports Med Rep. 2014; 13(1): 45-51.6. Smith LL. Tissue trauma: the underlying cause of overtraining syndrome? J Strength Cond Res. 2004; 18(1): 158-193.
  • 7. Krishandas R, Cavanagh J. Depression: an inflammatory illness? J Neurol Neurosurg Psychiatry. 2012; 83: 495-502.
  • 8. Hammond T, Gialloreto C, Kubas H, HapDavis H4th. The prevalence of failure-based depression among elite athletes. Clin J Sport Med. 2013; 23(4): 273-277.
  • 9. Armstrong L, Van Heest L. The unknown mechanism of the overtraining syndrome – clues from depression and psychoneuroimmunology. Sports Medicine. 2002;32185-32209.
  • 10. Humphrey JH, Yow DA, Bowden WW. Stress in college athletics: Causes, consequences, coping. Binghamton, NY: The Haworth Half-Court Press, 2000.
  • 11. Nixdorf I, Hautzinger M, Beckmann J. Prevalence of depressive symptoms and correlating variables among German elite athletes. J Clin Sport Psych. 2013; 7(4):313-326.
  • 12. Gulliver A, Griffiths KM, Mackinnon A, et al. The mental health of Australian elite athletes. J Sci Med Sport. 2014; DOI:10.1016/j.jsams.2014.04.006.
  • 13. Wylleman P, Alfermann D, Lavallee D. Career transitions in sport: European perspectives. Psychol Sport Exerc. 2004; 5: 7-20.
  • 14. Didehbani N, Munro Cullum C, Mansinghani S, et al. Depressive symptoms and concussions in aging retired NFL players. Arch Clin Neuropsychol. 2013; 28(5): 418-424.
  • 15. Leddy MH, Lambert MJ, Ogles BM. Psychological consequences of athletic injury among high-level competitors. Res Q Exerc Sport. 1994; 65(4): 347-354.
  • 16. Strain J, Didehbani N, Cullum CM, et al. Depressive symptoms and white matter dysfunction in retired NFL players with concussion history. Neurology. 2013; 81(1): 25-32.
  • 17. Schaal K, Tafflet M, Nassif H, et al. Psychological balance in high level athletes: gender-based differences and sport-specific patterns. PLoS One. 2011; 6(5): e19007.
  • 18. Baum AL. Concussive injury, suicidal ideation in a 16-year old female athlete. Psychiatric Annals. 2012; 42(10): 361-363.
  • 19. Smith LL, Miles MP. Exercise-induced muscle injury and inflammation. In: Garret WE. and Kirkendall DT, eds., Exercise and sport science. Lippincot Wiliams&Wilkins, Philadelphia, 2000.
  • 20. Ostapiuk-Karolczuk J, Zembroń-Łacny A, Naczk M, et al. Cytokines and cellular inflammatory sequence in non-athletes after prolonged exercise. J Sports Med Phys Fitness. 2012; 52(5): 563-568.
  • 21. Brunelli DT, Rodrigues A, Lopes WA, et al. Monitoring of immunological parameters in adolescent basketball athletes during and after a sports season. J Sports Sci. 2014; 32(11): 1050-1059.
  • 22. Nieman DC, Konrad M, Henson DA, et al. Variance in the acute inflammatory response to prolonged cycling is linked to exercise intensity. J Interferon Cytokine Res. 2012; 32(1): 12-17.
  • 23. Tidball JG, Villalta SA. Regulatory interactions between muscle and the immune system during muscle regeneration. Am J Physiol Regul Inter Comp Physiol. 2010; 298(5): 1173-1178.
  • 24. Kharraz Y, Guerra J, Mann CJ, et al. Macrophage plasticity and the role of inflammation in skeletal muscle repair. Mediators Inflamm. 2013; 491497.
  • 25. Tisoncik JR, Korth MJ, Simmons CP, et al. Into the eye of cytokine storm. Microbiol Mol Biol Rev. 2012; 76(1): 16-32.
  • 26. Pedersen L, Hojman P. Muscle-to-organ cross talk mediated by myokines. Adipocyte. 2012; 1(3): 164-167.
  • 27. Muñoz-Cánoves P, Scheele C, Pedersen BK, et al. Interleukin-6 myokine signaling in skeletal muscle: a double-edged sword? FEBS J. 2013; 280(17): 4131-4148.
  • 28. Moldoveanu AI, Shepard RJ, Shek PN. The cytokine response to physical activity and training. Sports Med. 2001; 31: 115-144.
  • 29. Bassel-Duby R, Olson EN. Signaling pathways in skeletal muscle remodeling. Annu Rev Biochem. 2006; 75: 19-37.
  • 30. Vitkovic L, Bockaert J, Jacque C. “Inflammatory” cytokines: neuromodulators in normal brain? J Neurochem. 2000; 74(2): 457-471.
  • 31. Suzuki K, Nakaji S, Yamada M, et al. Systemic inflammatory response to exhaustive exercise. Cytokine kinetics. Exerc Immunol Rev. 2002; 8: 6-48.
  • 32. Hackney AC, Koltun KJ. The immune system and overtraining in athletes: clinical implications. Acta Clin Croat. 2012; 51: 633-641.
  • 33. Pedersen KB. Muscles and their myokines. J Exp Biol. 2011; 214: 337-346.
  • 34. Guzmán C, Hallal-Calleros C, López-Griego L, et al. Interleukin-6: A cytokine with a pleiotropic role in the neuroimmmunoendocrine network. The Open Neuroendocrinology Journal. 2010; 3: 152-160.
  • 35. Feokitistov I, Biaggioni I. Role of adenosine A2B receptors in inflammation. In: Jacobson KA, Linden J, eds., Pharmacology of purine and pyrimidine receptors. Oxford: Advances in Pharmacology, 2011.36. Dantzer R, O’Connor JC, Freund GG, et al. From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci. 2008; 9(1): 46-56.
  • 37. Olusoga P, Butt J, Hays K, et al. Stress in elite sports coaching. Identifying stressors. J App Sport Psych. 2009; 21(4): 442-459.
  • 38. Raison CL, Capuron L, Miller AH. Cytokines sing the blues: inflammation and the pathogenesis of depression. TRENDS in Immunology. 2006; 27(1): 24-32.
  • 39. Loftis JM, Huckans M, Morasco BJ. Neuroimmune mechanisms of cytokine-induced depression: Current theories and novel treatment strategies. Neurobiol Dis Mar. 2010; 37(3): 519-533.
  • 40. Maes M, Berk M, Goehler L, et al. Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways. BMC Medicine. 2012; 10: 66.
  • 41. Messay B, Lim A, Marshland AL. Current understanding of the bi-directional relationship of major depression with inflammation. BMAD. 2012; 2: 4.
  • 42. Dowlati Y, Herrmann N, Swardfager W, et al. Metaanalysis of cytokines in major depression. Biol Psychiatry. 2010; 67: 446-457.
  • 43. Zunszain PA, Hepqul N, Pariante CM. Inflammation and depression. Curr Top Behav Neurosci. 2013; 14: 135-151.
  • 44. Linden W. Stress management: From basic science to better practice. Thousand Oaks, CA: Sage, 2004.
  • 45. Stark JL, Avitsur R, Padgett DA, et al. Social stress induces glucocorticoid resistance in macrophages. Am J Physiol Regul Inter Comp Physiol. 2001; 280(6): R1799-1805.
  • 46. Morgan WP, Brown DR, Raglin JS, et al. Psychological monitoring of overtraining and staleness. Br J Sports Med. 1987; 21(3): 107-114.
  • 47. Plowman SA, Smith DL. Exercise physiology for health, fitness, and performance [2nd ed.]. Philadelphia, PA: Lippincott Williams & Wilkins, 2008.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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