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Czasopismo

2013 | 07 | 4 |

Tytuł artykułu

Laser-induced interstitial thermotherapy in treatment of solid nodules of thyroid

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Introduction. pending on the application of laser-induced interstitial thermotherapy (LITT) in the treatment of solid thyroid nodules for today is the definition of indications and contraindications, techniques and technology performance, efficiency and improved long-term results. The aim of the study. Studing the effect of LITT on parathyroid tissue and functional capacity of thyroid gland, determining the factors affecting the timing of replacement of host connective tissue and its capacity to develop evidence to reapply thermotherapy. Materials and methods. using the LITT there were treated 272 patients with a nodular goiter with no signs of cystic degeneration. All patients – women from 22 to 68 years. The volume of nodules was within the range from 0.8 to 5.0 cm3. On ultrasonic characteristics, in particular echoic nodules were: 46 – hypoechoic, 189 – isochoric and 37 – hyperechoic. There was used a diode laser Lakhta Milon. LITT was performed on such parameters: the wavelength of 1060 nm, continuous operation, output power ranging from 2.5 to 3.2 watts. LITT was controlled by ultrasound. Changes in the nodule, parathyroid tissue and gland function after LITT was determined on the second day after 2 weeks, 1, 3, 6, 9 and 12 months after the procedure. Results and discussion. on the second day after laser thermotherapy aseptic inflammation develops in nodules, but their size increases on 25–30 %. Later, in a certain period the survey, the size of nodules decreased, rates of hormonal function did not changed. 6 months after LITT with sizes of nodules up to 2 cm3 complete replacement of connective tissue occurred in all cases of hypo- and isochoric nodes and 71% - hyperechoic, and in sizes from 2 to 5 cm3 – 75% of hypoechoic structures, 18 % and isochoric there was no beneficial effect hyperechoic nodes. In cases of treatment failure called for the repeated LITT, after which all patients had complete reduction of the nodule. Conclusions. in the developed mode LITT does not cause destructive changes in parathyroid tissue and hormonal gland function. Duration of regression and replacement of the nodule by connective tissue determines it’s echogenicity and volume. Indications for re-use of thermotherapy is the residual tissue at the nodule within the more than 42 % of the initial volume in six months after treatment and the presence in it thyroid epithelium.

Wydawca

-

Czasopismo

Rocznik

Tom

07

Numer

4

Opis fizyczny

p.86-90,fig.,ref.

Twórcy

  • Department of General and Operative Surgery with Topographic Anatomy, Khmel'nitskogo str 6a/3, Ternopil, Ukraine
  • Department of General and Operative Surgery with Topographic Anatomy, Khmel'nitskogo str 6a/3, Ternopil, Ukraine

Bibliografia

  • 1. Cakir B., et al. (2009), Initial Report of the Results of Percutaneous Laser Ablation of Benign Cold Thyroid Nodules: Evaluation of Histopathological Changes After 2 Years. Endocrine Patology. Vol. 20, №3: p. 170–176.
  • 2. Cakir B., Topaloglu O., Gul K. et al. (2006), Effects of percutaneous laser ablation treatment in benign solitary thyroid nodules on nodule volume, thyroglobulin and antithyroglobulin levels, and cytopathology of nodule in 1 yr followup. J. Endocrinol. Invest. Vol. 29: p. 876–884.
  • 3. Dossing H., Bennedbaek F.N., Hegedus L., (2006). Effect of Ultrasound-Guided Interstitial Laser Photocoagulation on Benign Solitary Solid Cold Thyroid Nodules: One versus Three Treatments. Thyroid. Vol. 16(8): p. 763–768.
  • 4. Faizrakhmanov A.B. (2006), The effectiveness of laser-induced thermotherapy for the treatment of non-toxic nodular goiter. Abstract. diss. Candidate. honey. Science. - Surgery - 14. 00. 27. Chelyabinsk: p.23.
  • 5. Grinyova E. (2003), How to treat non-toxic nodular goiter: a modern approach to the problem. – http://www. rusvrach.rU/journals/vrach/2003/6/
  • 6. Mogutov M.S. (2009), Ultrasound assisted surgery for thyroid disease. Author. diss. Doctor. honey. Science, 14.00.19 - radiology, radiation therapy, 14.00.27 - surgery – Moscow: p. 43.
  • 7. Papini E., Guglielmi R., Bizzarri G., et al. (2007), Treatment of Benign Cold Thyroid Nodules: A Randomized Clinical Trial of Percutaneous Laser Ablation Versus Levothyroxine Therapy or Follow-up. Thyroid. Vol. 17(3):p.229-235
  • 8. Privalov V.A. et al. (2002), Laser-induced interstitial thermotherapy in the treatment of recurrent goiter - Perm. 4th International Scienti􀏐ic and Practical Conference. Actual problems of endocrinology: p. 143-144.
  • 9. Shidlovskiy V.A., Shidlovskiy A.V. (2009), Ef􀏐iciency of laser-induced interstitial thermotherapy in the treatment of nodular goiter. Ukrainian Journal of Surgery. Issue. 4: p. 137-140.
  • 10. Valcavi R., Riganti F., Bertani A., Formisano D., Pacella C.M. (2010), “Percutaneous Laser Ablation of Cold Benign Thyroid Nodules: A 3-Year Follow-Up Study in 122 Patients”. Thyroid. 20: p. 11

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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