Cutaneous leishmaniasis mimicking granulomatous cheilitis and treated successfully with oral fluconazole in a boy

• Autorzy: Serarslan G. , Aksakal M.
• Języki publikacji: EN

Abstrakty

EN

Cutaneous leishmaniasis is a protozoan infectious disease and widespread in Mediterranean basin including Turkey. Lesions usually start with erythematous papules, gradually enlarges and afterwards it ulcerates. We present a 12-year-old boy with diffuse persistent lip swelling mimicking granulomatous cheilitis. Systemic glucantime was started. However, severe hypotension and bradycardia was developed after injection. Oral fluconazole was started and the lesion resolved completely. Cutaneous leishmaniasis can have varied clinical manifestations and should be suspected especially in endemic areas. Oral fluconazole seems to be safe and effective treatment modality in paediatric cases.

Słowa kluczowe

EN

cutaneous leishmaniasis; leishmaniasis; protozoan parasite; parasitic disease; human disease; mimicking granulomatous cheilitis; oral dose; fluconazole; boy

• Wydawca: -
• Czasopismo: Annals of Parasitology
• Rocznik: 2015
• Tom: 61
• Numer: 3
• Opis fizyczny: p.197-199,fig.,ref.

Twórcy

autor

Serarslan G.

• Department of Dermatology, Faculty of Medicine, Mustafa Kemal University, İskenderun St., Hatay 31100, Turkey

autor

Aksakal M.

• Department of Dermatology, Faculty of Medicine, Mustafa Kemal University, İskenderun St., Hatay 31100, Turkey

Bibliografia

• [1] Ok Ü.Z., Balcıoğlu İ.C., Taylan Özkan A., Özensoy S., Özbel Y. 2002. Leishmaniasis in Turkey. Acta Tropica 84: 43-48.
• [2] Dassoni F., Abebe Z., Naaf B., Morrone A. 2013. Cutaneous and mucocutaneous leishmaniasis resembling borderline-tuberculoid leprosy: a new clinical presentation? Acta Dermato-Venereologica 93: 74-77.
• [3] Toz S.O., Nasereddin A., Ozbel Y., Ertabaklar H., Culha G., Sevil N., Alkan M.Z., Jaffe C.L. 2009. Leishmaniasis in Turkey: molecular characterization of Leishmania from human and canine clinical samples. Tropical Medicine and International Health 14: 1401-1406.
• [4] Uzun S., Uslular C., Yücel A., Acar M.A., Özpoyraz M., Memişoğlu H.R. 1999. Cutaneous leishmaniasis: evaluation of 3074 cases in the Çukurova region of Turkey. British Journal of Dermatology 140: 347- 350.
• [5] Baron S., Laube S., Raafat F., Moss C. 2004. Cutaneous leishmaniasis in a Kosovan child treated with oral fluconazole. Clinical and Experimental Dermatology 29: 546-547.
• [6] Veraldi S., Bottini S., Persico M. C., Lunardon L. 2007. Case report: leishmaniasis of the upper lip. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology 104: 659-661.
• [7] Veraldi S., Rigoni C., Gianotti R. 2002. Leishmaniasis of the lip. Acta Dermato-Venereologica 82: 469-470.
• [8] Amin M., Manisali M. 2000. Cutaneous leishmaniasis affecting the face: report of a case. Journal of Oral and Maxillofacial Surgery 58: 1066-1069.
• [9] Crogan J., Gunasekera H., Wood N., Sheikh M., Isaacs D. 2010. Management of old world cutaneous leishmaniasis in refugee children. Pediatric Infectious Disease Journal 29: 357-359.
• [10] Maillo-Monge B., Velez-Lopez R. 2013. Thera peu tic options for old world cutaneous leishmaniasis and new world cutaneous and mucocutaneous leishma - niasis. Drugs 73: 1889-1920.
• [11] Alrajhi A., Ibrahim E.A., De Vol E.B., Khairat M., Faris R.M., Maguire J.H. 2002. Fluconazole for the treatment of cutaneous leishmaniasis caused by Leishmania major. New England Journal of Medicine 346: 891-895.
• [12] Emad M., Hayati F., Fallahzadeh M.K., Namazi M.R. 2011. Superior efficacy of oral fluconazole 400 mg daily versus oral fluconazole 200 mg daily in the treatment of cutaneous Leishmania major infection: a randomized clinical trial. Journal of the American Academy of Dermatology 64: 606-607.
• [13] Toubiana J., Armengaud J.B., Camet J.D., Gendrel D. 2006. Oral fluconazole treatment for extensive cutaneous leishmaniasis in an 11-year-old child. Pediatric Infectious Disease Journal 25: 1083-1084.

Identyfikatory

DOI

10.17420/ap6103.08