Chronic treatment with desmethylimipramine increases the oxytocin content in the hypothalamus and neurohypophysis of normal and pinealectomized male rats

• Autorzy: Juszczak M.
• Języki publikacji: EN

Abstrakty

EN

Juszczak, M.: Chronic treatment with desanefhylimipraimine increases the oxytocin content in the hypothalamus and neurohypophysis of normal and pinealectomized male rats. Acta physiol, pol., 1988, 39 (4): 261-268. The, effect of chronic treatment with desmethylimipramine (i.p., 10 mg/kg; twice daily over 5 days) on the content of oxytocinin the hypothalamus and neurohypoiphysis of normal and pinealectomized male rats has been investigated. Pinealectomy resulted in a decrease of oxytocin content in the hypothalamus and neurohypophysis. Treatment with desmethylimipra- mine (desipramine; DMI) was followed by a distinct increase of the oxytocin potency in the hypothalamus and neurohypohysis in both normal and pinealectomized rats. It may be supposed that chronic treatment with DMI inhibits the oxytocin release from neurohypophysis.

• Wydawca: -
• Czasopismo: Acta Physiologica Polonica
• Rocznik: 1988
• Tom: 39
• Numer: 4
• Opis fizyczny: p.261-268,ref.

Twórcy

autor

Juszczak M.

• Department of Pathophysiology, School of Medicine, Lodz, Poland

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