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1961 | 07 | 3 |
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Uwagi w sprawie leczenia adipinianem piperazyny niektórych schorzeń pasożytniczych przewodu pokarmowego

Autorzy
Treść / Zawartość
Warianty tytułu
EN
Remarks on the question of treatment of some parasitic diseases with piperasine adipate
RU
Primechanija k voprosu lechenija nekotorykh parazitnykh zabolevanijj pishhevaritel'nogo trakta pri pomoshhi adipata piperazina
Języki publikacji
PL
Abstrakty
EN
The author quotes the results of treatment with piperasine adipate of Oxyuriasis and Ascariasis. He applied the afore said preparation, giving it to five groups of persons infested with Enterobius vermicularis. In the I group, which counted 100 persons, the medicine was given in 3 curative cycles of 7 days with weekly breaks, the dose being 30 mg/kg of the body weight every 24 hours. As result of such a treatment 73 per cent of cases proved to be cured. In the II group, counting 200 persons, in which the invasion of parasites was very intensive or where the conditions of the surroundings were favourable to further infestation the medication was similar to the one applied in the former group, except that during 8 or 10 weeks piperasine adipate was given in supporting doses twice a week, the ratio being 20-30 mg/kg every 24 hours. In the III group composed of 100 patients the drug was given in the same way as for patients in group II but the first cycle of the cure we.s prolonged to 10 days. The results were 85 per cent of persons cured. In the IV group piperasine adipate was also administered as in group II but in the first week of the treatment the dose of the preparation was rised to a ratio of 50 mg/kg. 88 per cent of the patients were cured. Group V passed the same treatment with pipernsine adipate as group II, with addition of an enema applied once per day and composed of a solution of piperasine in a ratio of 20 mg/kg in 200 ml of warm water. The result was 94 per cent of cured persons. In order to prevent itching in the anus or to make it milder the author suggests application of wadded suppositories embalmed with 4 per cent anaestesine unguentum during the whole period of the cure. In the treatment of Ascariasis the author gave the patients belonging to the first group piperasine adipate during 7 days, the dose ratio being 30 mg/kg. The results obtained were 94 per cent of cured. In the II group the preparation was administered in a dose ratio of 50 mg/kg. every 24 hours, the results of the cure bting 98 per cent. Administration of the drug in Enterobius infestation proved to be inefficacious.
Słowa kluczowe
PL
Wydawca
-
Rocznik
Tom
07
Numer
3
Opis fizyczny
s.567-577,tab.,bibliogr.
Twórcy
autor
  • I Klinika Chorób Wewnętrznych, Akademia Medyczna w Łodzi, Łódź
Bibliografia
  • 1. Bluger A. F., Gagaine A. E., Dachowker S. E., Mincenhof L. A., Ratenberg N. S. i Czarnyj S. D.: Srawnitlelnyje riezultaty primienienija piperazin-adipinata i kisłoroda pri leczenii bolnych askaridozom. - Med. parazitologija i parazit. boleźni, 26, 1: 77-80, 1957.
  • 2. Brown H. W.: The treatment of Ascaris lumbricoides infections with piperazine. - J. of Pediatrics, 45: 419-425, 1954.
  • 3. Brown H. W.: Treatment of intestinal parasitic infection encountered in North America. - Seminar Report Merck Sharp & Dohme, 2, 1: 22-28, 1957.
  • 4. Brown H. W. i Chan K. F.: Treatment of Enterobius vermicularis infections with piperazine. - Amer. J. Trop. Med. and Hyg., 4, 2: 321-324, 1955.
  • 5. Brown H. W., Chan K. F. i Hussey K. L.: The efficacy of piperazine compounds against Symphacia obvelata, a pinworm of mice. - Amer. J. Trop. Med. and Hyg. 3, 3: 504-510, 1954.
  • 6. Brown H. W. i Sterman M.M.: Treatment of Ascaris Zumbricoides infections with piperazine citrate. - Amer. J. Trop. Med. and Hyg., 3, 4: 750-754, 1954.
  • 7. Bumbalo T. S., Gustina F. J. i Oleksiak R. E.: The treatment of pinworm infection (enterobiasis). - J. of Pediatrics, 44, 4: 386-391, 1954.
  • 8. Cross B. G., David A. i Vallance D. K.: Piperazine adipate; a new anthelmintic agent. Part II. Toxological and pharmacological studies. - J. Pharm. and Pharmacol., 6, 10: 711-717, 1954.
  • 9. Davies M. T., Forrest J., Hartley F. i Petrow W.: Piperazine adipate a new anthelmintic agent. Part I. Physico-chemical properties. - J. Pharm. and Pharmacol., 6, 10: 707-710, 1954.
  • 10. Dunn T. L.: Effect of piperazine derivativas on certain intestinal helminths. - The Lancet, 3, 19: 592-593, 1955.
  • 11. Fields D. N., Selly G. W. i Guicherit I. D.: The treatment of Ascariasis with piperazine. - Documenta de Med. Geogr. et Trop., 8: 80-84, 1956.
  • 12. Gerwel Cz.: Najwłaściwsze metody rozpoznawcze i lecznicze schorzeń pasożytniczych przewodu pokarmowego człowieka. - Wiad. Parazytoz., 2, 1: 3-17, 1956.
  • 13. Grott J. W., Dzięciołowski Z. i Kuźmicki R.: Czarne jagody jako ważny czynnik leczniczy w zwalczaniu owsicy. - Wiad. Lek., 6, 9: 420-462, 1953.
  • 14. Goeters W.: Zur Behandlung der Oxyuriasis im Kindesalter. - Dtsch. Med. Wschr. , 80, 9: 312-313, 1955.
  • 15. Hanzlik P. J.: Piperazine and other organie urate solvents. - J. Lab. Clin. Med., 2: 308, 1917.
  • 16. Hill R. D.: Mass therapy with piperazine adipate in the control of threadworm infestations. - Brit. Med. J., (11. 17), 1156-1159, 1956.
  • 17. Hucker A. G. i Schofield F. D.: Whipworm infections. - Brit. Med. J., (11. 17), 1159-1160, 1956.
  • 18. Krotow A. I.: Miechanizm diejstwa piperazina na askarid. - Med. parazitologija i parazit. boleźni, 26, 3: 284-289, 1957.
  • 19. Kuźmicki R.: Owsica (enterobiasis) i leczenie jej czarnymi jagodami – Biul. In). C.Z.A. 5, 8: 28-30, 1955.
  • 20. Mouriquand G., Roman E. i Coisnard J.: Essai de traitement de l'oxyurose par la piperasine. - J. Med. de Lyon, 32, 748: 189-195, 1951.
  • 21. Pawłowski Z. i Rydzewski A.: Piperazyna w ambulatoryjnym leczeniu owsicy. - Wiad. Parazytoz.. 2, 5: 271-282, 1956.
  • 22. Pawłowski Z. i Rydzewski A.: Jednodniowa kuracja piperazyną w masowym leczeniu glistnicy (ascariasis). - Wiad. Parazytol., 2, 5, suppl.: 131-132, 1956.
  • 23. Rachelson M. H. i Ferguson W. R.: Piperazine in the treatment of enterobiasis. - Am. J. dis. of Children, 5, 89, 3: 346-349, 1955.
  • 24. Schroeder U.: Die Oxyuriasis als Gemeinschaftsinfektion und ihre Behandlung. - Dtsch. Med. J., 7, 14: 517-519, 1956.
  • 25. Schmidt J.: Erfahrungen mit Uvilon bei der Behandlung der Oxyuriasis Erwachsener. - Medizinische, 19: 718-719, 1955.
  • 26. Siemionowa H. E., Turczyns M. E. i Krotow A. I.: O leczeni i bołnych enterobiozom i askaridozom piperazinom. - Med. parazitologija i parazit. boleźni, 26, 4: 298-300, 1955.
  • 27. Standen O. D.: Activity of piperazine in vitro against Ascaris lumbricoides. - Brit. Med. J., 4930: 20-22, 1955.
  • 28. Warda L.: Działanie niektórych preparatów piperazynowych na jelitowe postacie włośni (Trichinella spiralis Owen 1835). - Wiad. Parazytol., 4, 5-6: 385-388, 1958.
  • 29. White R. H. i Standen O. D.: Piperazine in the treatment of threadworms in children. Report on a clinical trial. - Brit. Med. J., 4839: 755-757, 1953.
  • 30. White R. H. i Standen O. D.: Piperazine in the treatment of threadworms. - Brit. Med. J., s. 1272-1273, 1953.
  • 31. White R. H. i Standen O. D.: Piperazine in the treatment of threadworms. - Brit. Med. J., 4899: 460-461, 1954.
Typ dokumentu
Bibliografia
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Identyfikator YADDA
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