Lafutidine, a histamine H2 receptor antagonist with mucosal protective properties, attenuates 5-fluorouracil-induced intestinal mucositis in mice through activation of extrinsic primary afferent neurons

• Autorzy: Sano T. , Utsumi D. , Amagase K. , Matsumoto K. , Tominaga M. , Higuchi K. , Takeuchi T. , Kato S.
• Języki publikacji: EN

Abstrakty

EN

Słowa kluczowe

EN

mucositis; diarrhea; body weight loss; cancer chemotherapy; transient receptor potential vanilloid type 1; myeloperoxidase activity; inflammatory cytokine; histamine H2 receptor; lafutidine; 5-fluorouracil; mice; mouse

• Wydawca: -
• Czasopismo: Journal of Physiology and Pharmacology
• Rocznik: 2017
• Tom: 68
• Numer: 1
• Opis fizyczny: p.79-90,fig.,ref.

Twórcy

autor

Sano T.

• Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Yamashina, Kyoto, Japan
• Second Department of Internal Medicine, Osaka Medical College, Takatsuki, Osaka, Japan

autor

Utsumi D.

• Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Yamashina, Kyoto, Japan

autor

Amagase K.

• Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Yamashina, Kyoto, Japan

autor

Matsumoto K.

• Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Yamashina, Kyoto, Japan

autor

Tominaga M.

• Division of Cell Signaling, Okazaki Institute for Integrative Bioscience, National Institutes of Natural Sciences, Okazaki, Aichi, Japan

autor

Higuchi K.

• Second Department of Internal Medicine, Osaka Medical College, Takatsuki, Osaka, Japan

autor

Takeuchi T.

• Second Department of Internal Medicine, Osaka Medical College, Takatsuki, Osaka, Japan

autor

Kato S.

• Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Yamashina, Kyoto, Japan