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2012 | 15 | 2 |
Tytuł artykułu

Effect of infection of turkeys with haemorrhagic enteritis adenovirus isolate on the selected parameters of cellular immunity and the course of colibacillosis

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Języki publikacji
EN
Abstrakty
EN
The aim of the study was to determine the effect of a Polish low-virulence isolate of haemorrhagic enteritis adenovirus (HEV) on the immune system in turkeys and on the course of colibacillosis in birds infected under laboratory conditions. Turkeys were infected per os with HEV at the dose of 104.3EID50/mL and with E. coli (APEC) (serotypes 078:K80:H9) at the dose of 4×109CFU/mL by injection to the thoracic air sac. The birds infected with the HEV were infected with the APEC either simultaneously or after 5 days. Five days after HEV infection, the percentages of subpopulations of the CD3+CD4+ and CD3+CD8α+ T cells and the IgM+ B cells were determined in blood and spleens of the HEV-infected turkeys and in the control (uninfected) birds. The course of colibacillosis was more severe in turkeys infected with the APEC 5 days after infection with the HEV than in those infected with the HEV and APEC simultaneously and than in those infected only with APEC. Five turkeys out of the 18 infected with the APEC 5 days after infection with HEV, died. Their body weights were statistically significantly lower with higher FCR values 41 days after the infection in comparison to turkeys in the other groups. A considerable decrease in the percentage of the T and B cells subpopulations in the blood were found in turkeys infected with the HEV and while the percentage of CD3+CD4+ T cells subpopulation in the spleen increased significantly, the contribution of the CD3+CD8α+ T cells and IgM+ B cells subpopulations were decreased. These changes in the immune system of turkeys, occurring 5 days after infection with the HEV, made them more susceptible to infection with the APEC.
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-
Rocznik
Tom
15
Numer
2
Opis fizyczny
p.215-220,fig.,ref.
Twórcy
autor
  • Department of Poultry Diseases, Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowskiego 13, 10-718 Olsztyn, Poland
autor
autor
autor
Bibliografia
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  • Hess M, Raue R, Hafez HM (1999) PCR for specific detection of haemorrhagic enteritis virus of turkeys, an avian adenovirus. J Virol Methods 81: 199-203.
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  • Koncicki A (1996) Characteristics of domestic adenovirus isolates of hemorrhagic enteritis (HE) in turkeys and evaluation of epizootic situation in Poland. Acta Acad Agricult Tech Olst Veterinaria 22: 1-43.
  • Koncicki A, Jankowski J, Zduńczyk Z, Mazur-Gonkowska B, Krasnodębska-Depta A (2004) Effect of mannano-oligosacharides on the course of turkey infection with HEV and E. coli. Med Weter 60: 968-971.
  • Kothlow S, Mannes NK, Schaerer B, Rebeski DE, Kaspers B, Schultz U (2005) Characterization of duck leucocytes by monoclonal antibodies. Dev Comp Immunol 29: 733-748.
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Typ dokumentu
Bibliografia
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Identyfikator YADDA
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