Influence of some psychotropic drugs on the ethanol elimination by the isolated liver of rats chronically fed with ethanol

• Autorzy: Rajtar G. , Kleinrok Z.
• Języki publikacji: EN

Abstrakty

EN

Rajtar G. and Kleinrok Z.: Influence of some psychotropic drugs on the ethanol elimination by the isolated liver of rats chronically fed with ethanol. Acta Physiol. Pol. During a 4-week period the rats received ethanol (EtOH), as their only drinking fluid, in a concentration ranging from 6% to 20%. In the period of 72 hours after EtOH withdrawal the rats received diazepam (DZP), imipramine (IMI) or caffeine (CAFF) i.p. twice a day in a 12-hours interval. In the experiments carried out on the livers isolated from these rats, we observed the diminution of the rate of EtOH elimination from the perfusate by the livers of DZP and IMI treated rats. CAFF did not change the rate of EtOH elimination.

Słowa kluczowe

EN

psychotropic drug; ethanol elimination; liver; rat; chronic treatment; diazepam; imipramine; caffeine; interaction

• Wydawca: -
• Czasopismo: Acta Physiologica Polonica
• Rocznik: 1990
• Tom: 41
• Numer: 7
• Opis fizyczny: p.1-7,fig.,ref.

Twórcy

autor

Rajtar G.

• Department of Pharmacology, Medical Academy, Jaczewskiego 8, 20-090 Lublin, Poland

autor

Kleinrok Z.

• Department of Pharmacology, Medical Academy, Jaczewskiego 8, 20-090 Lublin, Poland

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