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2015 | 64 | 2 |
Tytuł artykułu

Characteristics of the Pseudomonas aeruginosa PA01 intercellular signaling pathway (Quorum Sensing) functioning in presence of porphyrins bismuth complexes

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The influence of synthetic and natural porphyrins bismuth complexes on P. aeruginosa quorum sensing system was carried out by detection of the pyocyanin, rhamnolipids and autoinducers biosynthesis level. The highest ability to reduce pyocyanin biosynthesis showed Bi(III)-TPP. Rhamnolipids production level also decreased in the presence of studied compounds. This effect was the most expressed in presence of 40 and 80 μM of the synthetic meso-substituted porphyrins. Autoinducers biosynthesis, especially 3-oxo-C₁₂-HSL was suppressed in presence of the bismuth complexes. That suggest that the mechanisms of action of this substances is an inhibition of signaling molecules or/and receptor for them.
Słowa kluczowe
Wydawca
-
Rocznik
Tom
64
Numer
2
Opis fizyczny
p.101-106,fig.,ref.
Twórcy
autor
  • Biotechnological Scientific-Educational Centre, I.I. Mechnikov Odessa National University, Odessa, Ukraine
autor
  • Department of Microbiology and Virology, I.I. Mechnikov Odessa National University, Odessa, Ukraine
autor
  • Biotechnological Scientific-Educational Centre, I.I. Mechnikov Odessa National University, Odessa, Ukraine
autor
  • Biotechnological Scientific-Educational Centre, I.I. Mechnikov Odessa National University, Odessa, Ukraine
autor
  • Department of Microbiology and Virology, I.I. Mechnikov Odessa National University, Odessa, Ukraine
Bibliografia
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Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
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