Expression of p16 (INK4a), cytokeratin 19, and Ki-67 in canine laryngeal squamous cell carcinoma

• Autorzy: Gandefer-Gola M. , Ciaputa R. , Nowak M. , Madej J. A.
• Języki publikacji: EN

Abstrakty

EN

The study aimed at morphological and immunohistochemical characteristics of laryngeal squamous cell carcinomas and their metastases in canine lymph nodes and lungs. Tissue sections were stained using classical technique with haematoxylin and eosin. In addition, immunohistochemical studies were performed with p16, cytokeratin, and Ki-67 antibodies. An expression of all examined antigens was detected in laryngeal tumours, while in tumour metastases only expression of p16 protein and cytokeratin was demonstrated. The results pointed to higher proliferative potential of the primary tumour than of their metastases.

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2013
• Tom: 57
• Numer: 3
• Opis fizyczny: p.399-405,fig.,ref.

Twórcy

autor

Gandefer-Gola M.

• Department of Pathomorphology and Forensic Veterinary Science, Department of Pathology, Wroclaw University of Environmental and Life Sciences, 50-375 Wroclaw

autor

Ciaputa R.

• Department of Pathomorphology and Forensic Veterinary Science, Department of Pathology, Wroclaw University of Environmental and Life Sciences, 50-375 Wroclaw

autor

Nowak M.

• Department of Pathomorphology and Forensic Veterinary Science, Department of Pathology, Wroclaw University of Environmental and Life Sciences, 50-375 Wroclaw

autor

Madej J. A.

• Department of Pathomorphology and Forensic Veterinary Science, Department of Pathology, Wroclaw University of Environmental and Life Sciences, 50-375 Wroclaw

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Identyfikatory

DOI

10.2478/bvip-2013-0069