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2011 | 14 | 2 |
Tytuł artykułu

The possibilities of practical application of transgenic mammalian species generated by somatic cell cloning in pharmacology, veterinary medicine and xenotransplantology

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Cloning of genetically-modified mammals to produce: 1) novel animal bioreactors expressing human genes in rens, urinary bladder and the male accessory sex glands, as well as 2) porcine organs suitable in pig-to-human xenotransplantology, could offer new advantages for biomedical purposes. So too does the generation and/or multiplication of genetically-engineered cloned animals in order to produce: 3) physiologically-relevant animal models of serious monogenic human diseases and 4) prion disease-resistant small as well as large animals (i.e., rodents, ruminants). The basic purpose of this paper is to overview current knowledge deciphering the possibilities of using transgenic specimens created by somatic cell nuclear transfer in medical pharmacology, veterinary medicine, agriculture, transplantational medicine and immunology.
Wydawca
-
Rocznik
Tom
14
Numer
2
Opis fizyczny
p.329-340,fig.,ref
Twórcy
autor
  • Department of Biotechnology and Animal Reproduction, National Research Institute of Animal Production, Krakowska 1, 32-083 Balice n.Krakow, Poland
  • Department of Biotechnology and Animal Reproduction, National Research Institute of Animal Production, Krakowska 1, 32-083 Balice n.Krakow, Poland
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Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.agro-2d13f3ea-5442-42b3-a4ce-86373bfb63cf
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