Comparative study of midazolam-propofol and metamizole-propofol clinical effects in domestic pigeons

• Autorzy: Mousavi A. , Abedi G. , Jahandideh A. , Hesaraki S.
• Języki publikacji: EN

Abstrakty

EN

This study was conducted to determine the quality of anesthesia by evaluating the clinical effects of midazolam-propofol and metamizole-propofol on domestic pigeons (Columba livia). The aim of the study was to choose an appropriate injectable anesthetic protocol by utilizing midazolam and metamizole as pre-anesthetic drugs in order to reduce the dose of propofol and decrease side effects. Eighteen male pigeons weighing 304.2 ± 32.3 g (mean ± SD) were randomly allocated to three groups of six pigeons each. Midazolam (6 mg/kg/IM) and metamizole (500 mg/kg/IM) were used five minutes prior to administration of propofol (8 mg/kg/IV) in groups I and II, respectively, while the birds in group III (control group) received metamizole (500 mg/kg/IM). Five minutes after the last injection, clinical parameters of various systems were evaluated. Nervous system parameters declined in groups I and II, while reflexes could still be elicited in group III (P < 0.05). There were no significant changes in the heart rate, dysrhythmia, or gastrointestinal parameters in the three groups (P > 0.05). The birds in group II showed reduced jaw and limb muscle tone (P < 0.05). Corneal and palpebral reflexes were absent in groups I and II (P < 0.05). Both respiratory depth and pattern were irregular in group I, while all the parameters were normal in group II (P < 0.05). The respiratory rate decreased in all groups after injection, although this reduction was significant only in group I (P < 0.05). In conclusion, the combination of metamizole-propofol is safer and more compatible with the physiology of pigeons and can be used for short operations, especially when inhalation agents are contraindicated.

Słowa kluczowe

EN

domestic animal; pigeon; veterinary medicine; anesthesia; metamizole; midazolam; propofol; clinical effect

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2018
• Tom: 74
• Numer: 09
• Opis fizyczny: p.581-586,ref.

Twórcy

autor

Mousavi A.

• Department of Clinical Sciences, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran

autor

Abedi G.

• Department of Clinical Sciences, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran

autor

Jahandideh A.

• Department of Clinical Sciences, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran

autor

Hesaraki S.

• Department of Pathobiology, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran

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Identyfikatory

DOI

10.21521/mw.6012