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2018 | 27 | 3 |

Tytuł artykułu

Vitality and implication of natural products from Viburnum Grandiflorum: an eco-friendly approach

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In this study we screened Viburnum grandiflorum for bioactive secondary metabolites and biological activity. Secondary metabolites were detected by phytochemical tests, and biological activity was confirmed through antimicrobial and anti-oxidant assays. Phytochemical screening (alkaloidal, tannins, terpenoids, flavonoids, anthraquinones, and glycosides) was performed with methanol, and aqueous and ethyl acetate extracts. Antibacterial activity against four bacterial strains — staphylococcus auries, Escherichia Coli, Bacillus subtillus, and salmonella typhi – were measured. Methanolic extract showed maximum inhibitory activity with diameter of zone of inhibition (11.66 mm), followed by n-hexane extract (9.33 mm) and then ethyl acetate extract. Four different fungi (Penicillium chrysogenum, Aspergillus flavus, Rhodotorula mucilaginosa, and Stachybotrys chartarum) were also tested against plant stem extract using different solvents. Dimethyl sulfoxide extract showed a maximum zone of inhibition at 20 mg/ml. Anti-oxidant activity of stem extract of Viburnum grandiflorum was evaluated by 1, 1-diphenyl- 2-picryl-hydrazyl (DPPH). Then we measured absorbance, and percentage activity at each concentration was found for three solvent extracts to get Ic50 values. These data support Viburnum grandiflorum as having enough potential to be used safely as an antimicrobial drug.

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Opis fizyczny



  • Department of Chemistry, Women University of Azad Jammu & Kashmir Bagh, Pakistan
  • Department of Chemistry, Govt. College Women University, Sialkot, Pakistan
  • Department of Chemistry, Lahore Garrison University, Lahore, Pakistan
  • Department of Zoology, Women University of Azad Jammu & Kashmir Bagh, Pakistan
  • Institute of Chemistry, Shah Abdul Latif University, Khairpur 66020, Sindh, Pakistan
  • Institute of Chemistry, Shah Abdul Latif University, Khairpur 66020, Sindh, Pakistan
  • Department of Chemistry, University of Agriculture, Faisalabad, Pakistan
  • Department of Chemistry, The University of Lahore, Lahore-Pakistan
  • Department of Chemistry, The University of Lahore, Lahore-Pakistan


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