Flow cytometry evaluation of phagocytic activity and oxygen metabolism of granulocytes in peripheral blood of rabbits with natural trichophytosis

• Autorzy: Wojcicka-Lorenowicz K. , Kostro K.
• Języki publikacji: EN

Abstrakty

EN

Cytometric evaluation of blood of rabbits naturally affected with trichophytosis showed a successive and significant increase in the percentage of phagocytic cells and the highest level of phagocytes was found on the 42nd d of the investigation. However, the analysis of phagocytic activity, oxygen metabolism (% of activated cells), and mean channel of fluorescence of granulocytes demonstrated a significant decrease on the 14th d and the highest mean values were obtained on the 42nd d of the investigation. An increase in phagocytic activity and oxygen metabolism of granulocytes on the 42nd d were observed during spontaneous recovery. The results of the presented study indicated that the non-specific cell-mediated immunity contributed to the elimination of the infection.

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2008
• Tom: 52
• Numer: 4
• Opis fizyczny: p.555-560,fig.,ref.

Twórcy

autor

Wojcicka-Lorenowicz K.

• Department of Epizootiology and Clinic of Infectious Diseases, Faculty of Veterinary Medicine, University of Life Science, 20-612 Lublin, Poland

autor

Kostro K.

• Department of Epizootiology and Clinic of Infectious Diseases, Faculty of Veterinary Medicine, University of Life Science, 20-612 Lublin, Poland

Bibliografia

• 1. Calderon R.A, Hay R.J.: Fungicidal activity of human neutrophils and monocytes on dermatophyte fungi, Trichophyton quinckeanum and Trichophyton rubrum. Immunology 1987, 61, 289-295.
• 2. Calderon R.A.: Immunoregulation of dermatophytosis. Critical Rev Microbiol 1989, 16, 339-368.
• 3. Dahl M.V.: Suppression of immunity and inflammation by products produced by dermatophytes. J Am Acad Dermatol 1993, 28, 19-23.
• 4. Gallo M.G., Tizzani P., Peano A., Rambozzi L., Meneguz P.G.: Eastern cottontail (Sylvilagus floridanus) as carrier of dermatophyte fungi. Mycopathology 2005, 160, 163- 166.
• 5. Gregurek-Novak T.: Effect of infection with Trichophyton mentagrophytes varietas interdigitale on phagocytosis in humans. Eur Acad Dermatol Venereol 2004, 18, 160-163.
• 6. Jones H.E.: Immune response and host resistance of humans to dermatophyte infection. J Am Acad Dermatol 1993, 28, 12-17.
• 7. King R.D., Khan H.A., Foye J.C., Greenberg J.H., Jones H.E: Transferrin, iron and dermatophytes. I. Serum dermatophyte inhibitory component definitively identified as unsaturated transferring. J Lab Clin Med 1975, 86, 204-212.
• 8. Kostro K., Gliński Z., Wojcicka-Lorenowicz K., Gacek L., Krakowski M.: Allopevac vaccine in prophylactics and controlling trichophytosis in rabbits. Medycyna Wet 2000, 56, 816-821.
• 9. Kostro K., Gliński Z., Wojcicka-Lorenowicz K., Nozdryn-Płotnicki Z.: Antiinfectious immunity of skin. Medycyna Wet 2002, 58, 655-660.
• 10. Kostro K., Gliński Z., Wojcicka-Lorenowicz K.: Immunological responses in dermatomycoses of animals. Medycyna Wet 2001, 57, 709-714.
• 11. Kostro K., Gliński Z.: Choroby Zakaźne. In: Patologia i Terapia Chorób Królików z Elementami Anatomii i Filologii, PWRiL, Warszawa, 2005, pp. 115-227.
• 12. Kostro K., Gliński Z.: The kinetics of the immune response to natural trichophytosis in arctic foxes. Folia Vet 2000, 44, 106-111.
• 13. Lomas J.G., Rodriguez F., Cavas M.L., Lopez I., Altuna A.: Immunology of dermatophytosis. Mycopathology 1983, 82, 29-32.
• 14. Nakajima H.: The pathophysiology and defense mechanism against superficial and subcutaneous fungal infection. Jpn J Med Mycol 2005, 46, 1-9.
• 15. Ogawa H., Summerbell R.C., Clemons K.V., Koga T., Ran Y.P., Rashid A., Sohnle P.G., Stevens D.A., Tsuboi R.: Dermatophytes and host defence in cutaneous mycoses. Med Mycol 1998, 1, 166-173.
• 16. Szili M., Kohalmi I.: Endemic Trichophyton mentagrophytes infection of rabbit origin. Mycosen 1981, 24, 412-420.
• 17. Van Rooij P., Detandt M., Nolard N.: Trichophyton mentagrophytes of rabbit origin causing family incidence of kerion: an environmental study. Mycoses 2006, 49, 426-430.
• 18. Wołoszyn S., Andrychiewicz J., Kostro K., Winiarczyk S., Grądzki Z.: Efficacy of vaccines in the control of dermatophytes of rabbits. Medycyna Wet 1996, 52, 518- 523.
• 19. Wołoszyn S., Umiński M.: Serological and allergic activity of native and pure trichophytin. Medycyna Wet 1985, 41, 394-398.