PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2013 | 55 | 1 |
Tytuł artykułu

Polyphenol composition of extract from aerial parts of Circaea lutetiana L. and its antioxidant and anti-inflammatory activity in vitro

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The chemical composition and bioactivity of a water/methanol extract prepared from aerial parts of Circaea lutetiana were determined. HPLC-DAD-MS3 analysis revealed the presence of 14 different compounds comprising phenolic acids, ellagitannins and flavonoids. Antioxidant assays showed the extract's strong scavenging activity towards DPPH (SC50 33.1±3.1 μg/ml), O2 - (SC50 4.0±2.3 μg/ml) and H2O2 (SC50 below 2 μg/ml). Enzyme-based studies revealed that Circaea lutetiana extract inhibits the activity of hyaluronidase (IC50 13.3±2.4 μg/ml) and lipoxygenase (IC50 44.7±1.4 μg/ml). These results support some traditional uses of Circaea lutetiana.
Słowa kluczowe
Wydawca
-
Rocznik
Tom
55
Numer
1
Opis fizyczny
p.16-22,fig.,ref.
Twórcy
autor
  • Department of Pharmacognosy and Molecular Basis of Phytotherapy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland
  • Department of Pharmacognosy and Molecular Basis of Phytotherapy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland
autor
  • Department of Pharmacognosy and Molecular Basis of Phytotherapy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland
Bibliografia
  • AKULA US, and ODHAV B. 2008. In vitro 5-Lipoxygenase inhibition of polyphenolic antioxidants from undomesticatedplants of South Africa. Journal of Medicinal PlantsResearch 2: 207–212.
  • AVERETT JE, and BOUFFORD DE. 1985. The flavonoids and flavonoid systematics of Circaea (Circaeeae,Onagraceae). Systematic Botany 10: 363–373.
  • AVERETT JE, and RAVEN PH. 1984. Flavonoids of Onagraceae. Annals of the Missouri Botanical Garden 71: 30–34.
  • BOUFFORD DE. 1982. The systematics and evolution of Circaea (Onagraceae). Annals of the Missouri Botanical Garden69: 804–994.
  • BOUFFORD DE, RAVEN PH, AVERETT JE. 1978. Glycoflavones in Circaea. Biochemical Systematics and Ecology 6:59–60.
  • CHOI CW, KIM SC, HWANG SS, CHOI BK, AHN HJ, LEE MY, PARK SH, and KIM SK. 2002. Antioxidant activity and free radical scavenging capacity between Korean medicinalplants and flavonoids by assay-guided comparison. PlantSciences 163: 1161–1168.
  • FURUTA T, KIMURA T, KONDO S, MIHARA H, WAKIMOTO T, NUKAYA H, TSUJI K, and TANAKA K. 2004. Concise total synthesisof flavone C-glycoside having potent anti-inflammatoryactivity. Tetrahedron 60: 9375–9379.
  • GRANICA S, BAZYLKO A, KISS AK. 2012. Determination of macrocyclic ellagitannin oenothein B in plant materials byHPLC-DAD-MS: Method development and validation.Phytochemical Analysis 23: 582–587.
  • GRANICA S, and KISS AK. 2013. Secondary metabolites from aerial parts of Circaea lutetiana L. BiochemicalSystematics and Ecology 46: 26–28.
  • HEVESI BT, HOUGHTON PJ, HABTEMARIAM S, and KÉRY Á. 2009. Antioxidant and antiinflammatory effect of Epilobiumparviflorum Schreb. Phytotherapy Research 23:719–724.
  • KIM YC, and KINGSTON DGI. 1996. A new caprylic alcohol glycoside from Circaea lutetiana ssp. canadensis. Journalof Natural Products 59: 1096–1098.
  • KISS AK, BAZYLKO A, FILIPEK A, GRANICA S, JASZEWSKA E, KIARSZYS U, KOŚMIDER A, and PIWOWARSKI J. 2011.Oenothein B's contribution to the anti-inflammatory andantioxidant activity of Epilobium sp. Phytomedicine 18:557–560.
  • KISS AK, FILIPEK A, CZERWIŃSKA M, and NARUSZEWICZ M. 2010. Oenothera paradoxa defatted seeds extract and itsbioactive component penta-O-galloyl-β-d-glucosedecreased production of reactive oxygen species andinhibited release of leukotriene B4, interleukin-8, elastase,and myeloperoxidase in human neutrophils.Journal of Agricultural and Food Chemistry 58:9960–9966.
  • KISS AK, KAPŁON-CIEŚLICKA A, FILIPIAK KJ, OPOLSKI G, and NARUSZEWICZ M.2012. Ex vivo effects of an Oenotheraparadoxa extract on the reactive oxygen species generationand neutral endopeptidase activity in neutrophilsfrom patients after acute myocardial infarction.Phytotherapy Research 26: 482–487.
  • KISS AK, and NARUSZEWICZ M. 2012. Polyphenolic compounds characterization and reactive nitrogen species scavengingcapacity of Oenothera paradoxa defatted seed extracts.Food Chemistry 131: 485–492.
  • MAKKAR HPS. 2000. Quantification of tannins in tree foliage. Joint FAO/IAEA working document.
  • MÁRQUEZ-FLORES YK, MONTELLANO-ROSALES H, CAMPOS ALDRETE ME, and MELÉNDEZ-CAMARGO ME. 2009. Antiinflammatoryactivity of aqueous and methanolicextracts of Oenothera rosea L. Hér. ex Ait in the rat.Revista Mexicana de Ciencias Farmaceuticas 40:11–16.
  • MOERMAN DE. 1998. Native American Ethnobotany. Timber Press, Inc, Portland, USA.
  • O'DOWD Y, DRISS F, DANG PM, ELBIM C, GOUGEROT-POCIDALO MA, PASQUIER C, and EL-BENNA J. 2004. Antioxidant effect ofhydroxytyrosol, a polyphenol from olive oil: scavenging ofhydrogen peroxide but not superoxide anion producedby human neutrophils. Biochemical Pharmacology 68:2003–2008.
  • PIWOWARSKI JP, KISS AK, and KOZŁOWSKA-WOJCIECHOWSKA M. 2011. Anti-hyaluronidase and anti-elastase activityscreening of tannin-rich plant materials used in traditionalPolish medicine for external treatment of diseaseswith inflammatory background. Journal ofEthnopharmacology 137: 937–941.
  • SHIE JJ, CHEN CA, LIN CC, KU AF, CHENG TJR, FANG JM, and WONG CH. 2010. Regioselective synthesis of di-C-glycosylflavonespossessing anti-inflammation activities.Organic and Biomolecular Chemistry 8: 4451–4462.
  • SHIKOV AN, POLTANOV EA, DORMAN HJD, MAKAROV VG, TIKHONOV VP, and HILTUNEN R. 2006. Chemical composition and invitro antioxidant evaluation of commercial water-solublewillow herb (Epilobium angustifolium L.) extracts.Journal of Agricultural and Food Chemistry 54:3617–3624.
  • WOJDYŁO A, OSZMIAŃSKI J, and CZEMERYS R. 2007. Antioxidant activity and phenolic compounds in 32 selected herbs.Food Chemistry 105: 940–949.
  • ZAUGG J, POTTERAT O, PLESCHER A, HONERMEIER B, and HAMBURGER M. 2006. Quantitative analysis of anti-inflammatoryand radical scavenging triterpenoid esters in eveningprimrose seeds. Journal of Agricultural and FoodChemistry 54: 6623–6628.
  • ZHOU G, and LV G. 2012. Comparative studies on scavenging DPPH free radicals activity of flavone C-glycosides from different parts of Dendrobium officinale. Zhongguo Zhongyao Zazhi 37: 1536–1540.
Uwagi
PL
Rekord w opracowaniu
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.agro-2695a2e8-6173-4a89-a0c0-a9e9282ea63b
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.