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2019 | 13 | 1 |

Tytuł artykułu

Building bridges between basic science and clinical medicine: a liberal arts perspective

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A critical issue for improving global health care is to better integrate basic science and clinical practice, as such integration will lead to innovative solutions. In this article, I will present models for how to prepare students to participate effectively on multidisciplinary teams that foster cooperation between scientists, medical centers, biotechnology businesses, and governmental bodies. I will provide examples of training programs in the United States (USA) designed to increase the number of and diversity of scientists and clinicians engaged in bridging basic science and clinical medicine, also called translational research. The training programs target different stages in career development, from pre-medical students through early career faculty, and have varied organisational structures. Many of the programs have existed long enough for institutions to be able to evaluate their effectiveness, and despite the different program contexts, there are key characteristics common to all of the programs that correlate with successful outcomes. Many of these characteristics can be adapted to other career stages and settings. I will summarize these and describe an example of an interdisciplinary, integrated science course for undergraduates that introduces students at the earliest stage of their careers to addressing complex problems through teamwork. Finally, I will provide suggestions for how other institutions can implement training programs that will build bridges between basic science and clinical medicine.

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  • Institute for Genetics and Biotechnology, Fulbright Scholar, University of Warsaw, Poland
  • Claremont McKenna, Pitzer, and Scripps Colleges, 925 N. Mills Ave., Claremont, 91711, California, USA


  • 1. Rubio DM, Schoenbaum EE , Lee LS, Schteingart DE, Marantz PR , Anderson KE, et al. Defining translational research: implications for training. Acad Med 2010; 85: 470–475.
  • 2. Smith CL, Jarrett M, Bierer SB. Integrating clinical medicine into biomedical graduate education to promote translational research: strategies from two new PhD programs. Acad Med 2013 Jan; 88(1): 137–143.
  • 3. Siefert AL, Cartiera MS, Khalid AN, Nantel MC, Loose CR, Schulam PG , et al. The Yale Center for Biomedical Innovation and Technology (CBIT): one model to accelerate impact from academic health care innovation. Acad Med 2019; 94(4): 528–534.
  • 4. Ameredes BT, Hellmich MR, Cestone CM, Wooten KC, Ottenbacher KJ, Chonmaitree T, et al. The Multidisciplinary Translational Team (MTT) model for training and development of translational research investigators. Clin Trans Sci 2015; 8: 533–541.
  • 5. Comeau DL, Escoffery C, Freedman A, Ziegler TR, Blumberg HM. Improving clinical and translational research training: a qualitative evaluation of the Atlanta Clinical and Translational Science Institute KL2-mentored research scholars program. J Investig Med 2017 Jan; 65(1): 23–31.
  • 6. Estape ES, Quarshie A, Segarra B, San Martin M, Ríos R, Martínez K, et al. Promoting diversity in the clinical and translational research workforce. J Natl Med Assoc. 2018 Dec; 110(6): 598–605.
  • 7. Begg MD, Bennett LM, Cicutto L, Gadlin H, Moss M, Tentler J, et al. Graduate education for the future: new models and methods for the clinical and translational workforce. Clin Transl Sci 2015 Dec; 8(6): 787–792
  • 8. Choi PJ, Tubbs R, Oskouian RJ. The current trend of the translational research paradigm. Cureus 2018 Mar 19; 10(3): e2340.
  • 9. Durairajanayagam D, Kashou AH, Tatagari S, Vitale J, Cirenza C, Agarwal A. Cleveland Clinic’s summer research program in reproductive medicine: an inside look at the class of 2014. Med Educ Online 2015 Nov 11; 20: 29517.
  • 10. Ulsh L, Drew D, Purvis-Roberts KL, Edwalds-Gilbert G, Landsberg AS, Copp N. Accelerated Integrated Science Sequence (AISS): an introductory biology, chemistry and physics course. J Chem Educ 2009; 86(11): 1295–1298.

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