PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2014 | 70 | 06 |
Tytuł artykułu

Status of lipid peroxidation and some antioxidants in sheep with acute ruminal lactic acidosis

Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The purpose of this study was to evaluate the status of lipid peroxidation (LPO) and some antioxidants in sheep with acute ruminal lactic acidosis (ARLA). The material consisted of 20 Akkaraman sheep which had been diagnosed with ARLA and 20 healthy sheep of the same breed as the control group. The sheep were 1-2 years old. Ruminal fluid was obtained from the animals from both groups by means of a stomach tube and examined immediately. Blood samples were obtained from the jugular vein of the animals. The activites of catalase (CAT) and superoxide dismutase (SOD) as well as the levels of reduced glutatione (GSH) and malondialdehyde (MDA, a marker of LPO) were determined. Compared with the control group, the sheep with ARLA had a significantly higher level of MDA (p < 0.0001), whereas the activities of CAT and SOD and the level of GSH were significantly lower (p < 0.0001). In conclusion, this study highlights the occurrence of oxidative stress with important differences in antioxidant status, as reflected by the assessment of selected enzymatic and nonenzymatic antioxidants in sheep with ARLA and healthy controls. This indicates that the serum activities of SOD and CAT, as well as the levels of GSH and MDA, may be useful as indicators of LPO and antioxidant status in sheep with ARLA.
Słowa kluczowe
EN
Wydawca
-
Rocznik
Tom
70
Numer
06
Opis fizyczny
p.357-361,ref.
Twórcy
autor
  • Department of Internal Medicine, Faculty of Veterinary Medicine, Ataturk University, Erzurum, Turkey
  • Department of Biochemistry, Faculty of Veterinary Medicine, Ataturk University, Erzurum, Turkey
autor
  • Department of Internal Medicine, Faculty of Veterinary Medicine, Firat University, Elazıg, Turkey
  • Department of Biochemistry, Faculty of Veterinary Medicine, Ataturk University, Erzurum, Turkey
Bibliografia
  • 1. Al-Qudah K. M.: Oxidant and antioxidant profile of hyperketonemic ewes affected by pregnancy toxemia. Vet. Clin. Pathol. 2011, 40, 60-65.
  • 2. Amoli J. S., Baghbanzadeh A.: Oxidative stress in Sahal sheep of different age groups. Turk J. Vet. Anim. Sci. 2010, 34, 379-383.
  • 3. Anderson M. E.: Glutathione: an overview of biosynthesis and modulation. Chem. Biol. Interact. 1998, 111-112, 1-4.
  • 4. Atakisi E., Bozukluhan K., Atakisi O., Gokce H. I.: Total oxidant and antioxidant capacities and nitric oxide levels in cattle with traumatic reticuloperitonitis. Vet. Rec. 2010, 167, 908-909.
  • 5. Bogdan C., Rollinghoff A., Diefenbach M.: Reactive oxygen and reactive nitrogen intermediates in innate and specific immunity. Curr. Opin. Immunol. 2000, 12, 64-76.
  • 6. Braun U., Tihs R., Schefer U.: Ruminal lactic acidosis in sheep and goats. Vet. Rec. 1992, 130, 343-349.
  • 7. Celi P.: Biomarkers of oxidative stress in ruminant medicine. Immunopharmacol and Toxicol. 2011, 33, 233-240.
  • 8. Celi P.: Oxidative stress in ruminants, [in:] Mandelker L., Vajdovich P. (Eds.): Studies on Veterinary Medicine, Oxidative Stress in Applied Basic Research and Clinical Practice 5. Springer 2011, 191-231.
  • 9. Cenesiz S., Ozcan A.: Deneysel kronik florozis oluşturulmuş Tuj ırkı koyunlarda eritrosit süperoksit dismutaz, katalaz ve gultatyon peroksidaz aktivitelerinin araştırılması. Kafkas Univ. Vet. Fak. Derg. 2003, 9,161-164.
  • 10. Chihaya Y., Matsukawsa K., Mizushimaan S., Matsui Y.: Ruminant forestomach and abomasal mucormycosis under rumen acidosis. Vet. Pathol. 1988, 25, 119-123.
  • 11. Constable P. D.: Grain overload in ruminants, [in:] Khan C. (Ed.): The Merck Veterinary Manual. 10th ed, Whitehouse, Merck &Co, Inc. USA 2010, 200-203.
  • 12. Deger Y., Ertekin A., Deger S., Mert H.: Lipid peroxidation and antioxidant potential of sheep liver infected naturally with distomatosis. Turk. Parazitol. Derg. 2008, 32, 23-26.
  • 13. Del Rio D., Stewart A. J., Pellegrini N.: A review of recent studies on malondialdehyde as toxic molecule and biological marker of oxidative stress. Nutr. Metab. Cardiovasc. Dis. 2005, 15, 316-328.
  • 14. Djaldetti M., Salman H., Bergman M., Djaldetti R., Bessler H.: Phagocytosis – the mighty weapon of the silent warriors. Microsc. Res. Tech. 2002, 57, 421-431.
  • 15. Dshurov A.: Pathomorfologic changes in the ruminal acidosis of sheep. Arch. Exp. Veterinarmed. 1976, 30, 881-887.
  • 16. Duranay M., Yilmaz F. M., Yilmaz G., Akay H., Parpucu H., Yucel D.: Association between nitric oxide and oxidative stress in continuous ambulatory peritoneal dialysis patients peritonitis. Scand. J. Clin. Lab. Invest. 2007, 67, 654-660.
  • 17. Erisir M., Benzer F., Kandemir F. M.: Changes in the rate of lipid peroxidation in plasma and selected blood antioxidants before and during pregnancy in ewes. Acta Vet. Brno 2009, 78, 237-242.
  • 18. Esmaeilnejad B., Tavassoli M., Asri-Rezaei S., Dalir-Naghadeh B.: Evaluation of antioxidant status and oxidative stress in sheep naturally infected with Babesia ovis. Vet. Parasitol. 2012, 185, 124-130.
  • 19. Garry F. B.: Indigestion in ruminants, [in:] Smith B. P (Ed.): Large Animal Internal Medicine. 3rd ed, Mosby, St. Louis, Missouri 2002, 722-747.
  • 20. Gawel S., Wardas M., Niedworok E., Wardas P.: MDA as a lipid peroxidation marker. Wiad. Lek. 2004, 57, 453-455.
  • 21. Gazi M. R., Yokota M., Tanaka Y., Kanda S., Itabashi H.: Effects of protozoa on the antioxidant activity in the ruminal fluid and blood plasma of cattle. Anim. Sci. J. 2007, 78, 34-40.
  • 22. Gonzales R., Auclair C., Voisin E., Gautero H., Dhermy D., Boivin P.: Superoxide dismutase, catalase and glutathione peroxydase in red blood cells from patients with malignant diseases. Cancer Res. 1998, 44, 4137-4139.
  • 23. Goth L. A.: Simple method for determination of serum catalase activity and revision of reference range. Clin. Chim. Acta. 1991, 196, 143-152.
  • 24. Guo Y., Xu X., Zou Y., Yang Z., Li S., Cao Z.: Changes in feed intake, nutrient digestion, plasma metabolites, and oxidative stress parameters in dairy cows with subacute ruminal acidosis and its regulation with pelleted beet pulp. J. Anim. Sci. and Biotecnol. 2013, 4, 31-41.
  • 25. Halliwell B.: Antioxidant defence mechanism: from the beginning to the end (of the beginning). Free Rad. Res. 1999, 31, 261-272.
  • 26. Halliwell B., Chirico S.: Lipid peroxidation: its mechanism, measurement, and significance. Am. J. Clin. Nutr. 1993, 57, 715-725.
  • 27. Karapinar, T., Dabak M., Kizil O., Balikci E.: Severe thiamine deficiency in sheep with acute ruminal lactic acidosis. J. Vet. Intern. Med. 2008, 22, 662-665.
  • 28. Kataria A. K., Kataria N.: Evaluation of oxidative stress in sheep affected with Peste des petits ruminants. J. Stress Physiol.&Biochem. 2012, 8, 72-77.
  • 29. Kidd P. M.: Glutathione: Systemic protectant against oxidative and free radical damage. Altern. Med. Rev. 1997, 2, 155-176.
  • 30. Koracevic D., Koracevic G., Djordjevic V., Andrejevic S., Cosic V.: Method for the measurement of antioxidant activity in human fluids. J. Clin. Pathol. 2001, 54, 356-361.
  • 31. Lykkesfeldt J., Svendsen O.: Oxidants and antioxidants in disease: Oxidative stress in farm animals. Vet. J. 2007, 173, 502-511.
  • 32. Nagajara T. G., Lechtenberg K. F.: Acidosis in feedlot cattle. Vet. Clin. North Am. Food. Anim. Pract. 2007, 23, 333-350.
  • 33. Naito Y., Toshikazu Y., Kiich I. M., Nobuaki Y., Masahiro A., Yasunari N., Toshiro K., Norimasa Y., Motoharu K.: Neutrophils, lipid peroxidation, and nitric oxide in gastric reperfusion injury in rats. Free Rad. Biol. Med. 1998, 24, 494-502.
  • 34. Natarajan S. K., Mukhopadhya A., Ramachandran A., Amalanathan S., Kurian G., Balasubramanian K. A.: Spontaneous bacterial peritonitis results in oxidative and nitrosative stress in ascitic fluid. J. Gastroenterol. and Hepatol. 2007, 22, 177-181.
  • 35. Nazifi S., Razavi S. M., Kianiamin P., Rakhshandehroo E.: Evaluation of erythrocyte antioxidants mechanisms: antioxidiants enzymes, lipid peroxidation, and serum trace elements associated with progressive anemia in ovine malignant theileriosis. Parasitol. Res. 2011, 109, 275-281.
  • 36. Nour M. S. M., Abusamra M. T., Hago B. E. D.: Experimentally induced lactic acidosis in Nubian goats: clinical, biochemical and pathological investigations. Small Ruminant Res.1998, 31, 7-17.
  • 37. Owens F. N., Secrist D. S., Hill W. J., Gill D. R.: Acidosis in cattle: a review. J. Anim. Sci. 1998, 76, 275-286.
  • 38. Palmieri B., Sblendorio V.: Oxidative stress tests: overview on reability and use part I. Eur. Rev. Med. Pharmacol. Sci. 2007, 11, 309-342.
  • 39. Patra R. C., Lal S. B., Swarup D.: Biochemical profile rumen liquor, blood and urine in experimental acidosis in sheep. Small Ruminant Res. 1996, 19, 177-180.
  • 40. Radostits O. M., Gay C. C., Hinchcliff K. W., Constable P. D.: Veterinary Medicine. 10th ed, Saunders, USA 2007.
  • 41. Shan X. O., Aw T. Y., Jones D. P.: Glutathione dependent protection against oxidative injury. Pharmacol. Ther. 1990, 47, 61-71.
  • 42. Sun Y., Oberley L. W., Li Y.: A simple method for clinical assay of superoxide dismutase. Clin. Chem. 1988, 34, 497-500.
  • 43. Surapaneni K. M., Venkataramana G.: Status of lipid peroxidation, glutatione, ascorbic acid, vitamin E and antioxidant enzymes in patients with osteoartritis. Indian J. Med. Sci. 2007, 61, 9-14.
  • 44. Tietze F.: Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione. Anal. Biochem. 1969, 27, 502-522.
  • 45. Winrow V. R., Winyard P. G., Morris C. J., Blake D. R.: Free radicals in inflammation: second messengers and mediators of tissue destruction. Br. Med. Bull. 1993, 49, 506-522.
  • 46. Xu Y., Ding Z.: Physiological, biochemical and histopathological effects of fermantative acidosis in ruminant production: a minimal review. Span. J. Agric. Res. 2011, 9, 414-422.
  • 47. Yoshioka T., Kawada K., Shimada T., Mori M.: Lipid peroxidation in maternal and cord blood and protective mechanism against activated-oxygen toxicity in the blood. Am. J. Obstet. Gynecol. 1979, 135, 372-376.
Uwagi
Rekord w opracowaniu
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.agro-24c08025-51e4-4d2c-9774-f324794b2e6f
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.