Chaos deterministyczny drogą do kancerogenezy?

• Autorzy: Madej J.A.

Warianty tytułu

EN

Is a deterministic chaos the way to cancerogenesis?

• Języki publikacji: PL

Abstrakty

EN

On the basis of the 2nd law of thermodynamics, the study presents a probable process in which a neoplastic cell passes into the dissipative state on its thermodynamic branch and self-transforms into a neoplastic cell. The self-transformation is promoted by a long-term unstable, highly unbalanced state in which cells that are sensitive to cancerogenesis obtain their own thermodynamic branch, and their self-organization is probably based on a disturbed relationship between entropy and temperature. Self-organization is related to the progressive imbalance. It promotes mistakes during genetic copies formation , spontaneous mutations and, as a result, cancerogenesis. A deterministic chaos is a creative process because it is the only one capable of generating completely new structures, such as neoplasms. Neoplastic cells succeed only when their environment (extracellular matrix – ECM) is damaged due to e.g. senile inflammation or inflammation caused by the neoplasm itself. This is known as the oncogenesis adaptation theory and it explains the evolution of neoplastic cells. The mutation leading to the neoplastic transformation of a cell is sometimes unfavorable or even harmful to the cell by preventing its proper adaptation to surrounding tissues. This can be useful in adaptive therapy of some neoplasms.

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2020
• Tom: 76
• Numer: 04
• Opis fizyczny: s.195-199,rys.,bibliogr.

Twórcy

autor

Madej J.A.

• Zakład Patomorfologii i Weterynarii Sądowej, Katedra Patologii, Wydział Medycyny Weterynaryjnej, Uniwersytet Przyrodniczy we Wrocławiu, ul. Norwida 29, 50-375 Wrocław

Bibliografia

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Identyfikatory

DOI

10.21521/mw.6389