PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2010 | 19 | 5 |
Tytuł artykułu

Fungal contamination of air in the department of haematology

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The aim of this study was to test the air in a single hospital department for fungal contamination. The department included three fully protected rooms with laminar air flow, comprising a bone marrow transplant unit (BMTU) and eleven naturally ventilated patient rooms of a haematology unit (HAEMU). Air samples were taken with an IDEAL air sampler (bioMerieux) on Sabouraud dextrose agar plates. The concentration of fungi in the air of the HEPA-filtered rooms of the BMTU ranged from 0-75 CFU/m3. Penicillium and Cladosporium were dominant among the fungal biota in the whole department. Of aspergilli, A. fumigatus was prevalent and seasonal increases in the frequencies of A. clavatus and A. niger isolation were observed. The detection of potentially pathogenic species of Aspergillus and Mucor in the BMTU and an increased concentration of Aspergillus in the HAEMU (up to 200 CFU/m3) instigated the introduction of additional preventive measure besides routine disinfection, namely an exchange of the HEPA filters in the BMTU and the installation of equipment based on multifunctional ion technology in the HAEMU. In a subsequent examination, a diminished number of fungi in the air was observed. During the study, 2 cases of proven and 3 of probable aspergillosis (according to EORT criteria) were noted. There was no link observed between the higher concentration of Aspergillus detected in the hospital air and the development of the infection. The authors conclude that hospital air examination can be helpful in indicating problems with hospital air facilities, enabling the introduction of procedures improving air quality and subsequently diminishing the risk of nosocomial mycoses.
Wydawca
-
Rocznik
Tom
19
Numer
5
Opis fizyczny
p.967-971,ref.
Twórcy
autor
  • Department of Microbiology, Wroclaw Medical University, Chalubinskiego 4, 50-368 Wroclaw, Poland
  • Department of Haematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, Chalubinskiego 4, 50-368 Wroclaw, Poland
  • Department of Microbiology, Wroclaw Medical University, Chalubinskiego 4, 50-368 Wroclaw, Poland
  • Department of Microbiology, Wroclaw Medical University, Chalubinskiego 4, 50-368 Wroclaw, Poland
  • Department of Haematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, Chalubinskiego 4, 50-368 Wroclaw, Poland
autor
  • Department of Haematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, Chalubinskiego 4, 50-368 Wroclaw, Poland
  • Department of Clinical Chemistry, Wroclaw Medical University, Chalubinskiego 4, 50-368 Wroclaw, Poland
Bibliografia
  • 1. ASCIOGLU S, REX J.H., DE PAUW B., BENNETT J.E., BILLE J., CROKAERT F., DENNING D.W., DONNELLY J.P, EDWARDS J.E., ERJAVEC Z., FIERE D., LORTHOLARY O., MAERTENS J., MEIS J.F., PATTERSON T.F., RITTER J., SELLESLAG D., SHAH P.M., STEVENS D.A., WALSH T.J. Invasive fungal infections cooperative group of the European organization for research and treatment of cancer; mycoses study group of the national institute of allergy and infectious diseases. Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus. Clin. Infect. Dis., 34, 7, 2002.
  • 2. BHATTI Z., SHAUKAT A., ALMYROUDIS N.G., SEGAL B.H. Review of epidemiology, diagnosis, and treatment of invasive mould infections in allogeneic hematopoietic stem cell transplant recipients. Mycopathologia, 162, 1, 2006.
  • 3. AUBERGER J., LASS-FLÖRL C., ULMER H., NOGLERSEMENITZ E., CLAUSEN J., GUNSILIUS E., EINSELE H., GASTL G., NACHBAUR D. Significant alterations in the epidemiology and treatment outcome of invasive fungal infections in patients with haematological malignancies. Int. J. Hematol., 88, 508, 2008.
  • 4. MASCHMEYER G. Prevention of mould infections. J. Antimicrob. Chemother, 63, (1), 27,2009.
  • 5. HAHN T., CUMMINGS K.M., MICHALEK A.M., LIPMAN B.J., SEGAL B.H., MCCARTHY P.L. J.R. Efficacy of high-efficiency particulate air filtration in preventing aspergillosis in immunocompromised patients with hematologic malignancies. Infect. Control. Hosp. Epidemiol., 23, 525, 2002.
  • 6. CORNET M., LEVY V., FLEURY L., LORTHOLARY J., BARQUINS S., COUREUL M.H., DELIERE E., ZITTOUN R., BRÜCKER G., BOUVET A. Efficacy of prevention by high-efficiency particulate air filtration or laminar airflow against Aspergillus airborne contamination during hospital renovation. Infect. Control. Hosp. Epidemiol., 20, 508, 1999.
  • 7. SYMOENS F., BURNOD J., LEBEAU B., VIVIANI M.A., PIENS M.A., TORTORANO A.M., NOLARD N., CHAPUIS F., GRILLOT R. Hospital-acquired Aspergillus fumigatus infection: can molecular typing methods identify an environmental source? J. Hosp. Infect., 52, 60, 2002.
  • 8. DE VALK H.A., KLAASSEN C.H., MEIS J.F. Molecular typing of Aspergillus species. Mycoses. 51, 463, 2008.
  • 9. NOWICKA J., NAWROT U., WŁODARCZYK K., KULICZKOWSKI K. “One day” investigations as a method of estimation the mycobiota in patients with haematological neoplasms. Mikol. Lek. 14, 241, 2007 [In Polish].
  • 10. MORRIS G., KOKKI M.H., ANDERSON K., RICHARDSON M. Sampling of Aspergillus spores in air. J. Hosp. Infect., 44, 81, 2000.
  • 11. FALVEY D.G., STREIFEL A.J. Ten-year air sample analysis of Aspergillus prevalence in a university hospital. J. Hosp. Infect., 67, 35, 2007.
  • 12. KAŁUZNY J., MUSZYŃSKI Z., KAŁUZNY B.J. Ophthalmic operating theatre-chance of limiting contamination and infection risk. Part I. Decontamination of the microbial air pollution. Klin. Oczna, 110, 102, 2008 [In Polish].
  • 13. ALBERTI C., BOUAKLINE A., RIBAUD P., LACROIX C., ROUSSELOT P., LEBLANC T., DEROUIN F. Aspergillus study group. Relationship between environmental fungal contamination and the incidence of invasive aspergillosis in haematology patients. J. Hosp. Infect., 48, 198, 2001.
  • 14. HAIDUVEN D. Nosocomial aspergillosis and building construction. Med. Mycol., 47, (1), S210, 2009.
  • 15. RUPP M.E., IWEN P.C., TYNER L.K., MARION N., REED E., ANDERSON J.R.. Routine sampling of air for fungi does not predict risk of invasive aspergillosis in immunocompromised patients. J. Hosp. Infect., 68, 270, 2008.
  • 16. USNARSKA-ZUBKIEWICZ L., NAWROT U., NOWICKA J. Evaluation of mycobiota in patients with hematological malignancies in one-day examination. Adv. Clin. Exp. Med., 18, 55, 2009.
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.agro-1ff4a057-286b-4bbb-9f7e-8ea7f6be9b49
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.