PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2015 | 20 | 2 |
Tytuł artykułu

Effect of the addition of zinc and selenium ions on the stability of the Biolasol liquid used for perfusion, reperfusion and preservation of parenchymal organs of the abdominal cavity

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The Biolasol® liquid is an innovative solution used for perfusion, reperfusion and preservation of parenchymal organs of the abdominal cavity. Substances in the liquid prevent cellular oedema and help to maintain a proper water/mineral as well as acid/base balance in the intracellular environment. They also minimize free-radical injuries and ensure the integrity of the cellular membrane structure. The Biolasol® liquid has been shown to be much more efficient than the HTK liquid in the preservation of kidneys. The Biolasol® liquid containing 0.5 mM of vitamin C has been modified by adding ions of Se(IV), Zn(II), and their effect on the stability of the solution was examined. An accelerated aging test was applied to test the liquid stability. The test, based on the laws of chemical kinetics, was conducted at four temperatures at a 10°C step, that is: 50°C±0.05, 60°C±0.05, 70°C±0.05 and 80°C±0.05. The relative humidity equalled 75% of RH and the duartion of the test was 40 days. In order to determine the stability of the tested solutions, the Arrhenius Dependence equation was used, applied to the effect of temperature on the glucose decomposition reaction rate: lnk=lnA-(Ea/RT). The results indicate that the addition of zinc decreases the stability of the liquid by 30.5%, while the addition of selenium prolongs the stability by 8.21%. This is explained by the synergism of action of vitamin C and Se4+ antioxidant in the tested liquid. Zinc ions present in the solution increase the glucose decomposition reaction rate.
Wydawca
-
Rocznik
Tom
20
Numer
2
Opis fizyczny
p.377-384,fig.,ref.
Twórcy
  • Department of Applied Pharmacy, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia, Kasztanowa 3, 41-200 Sosnowiec, Poland
autor
  • Department of Applied Pharmacy, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia, Sosnowiec, Poland
autor
  • Department of General, Vascular and Transplant Surgery, School of Medicine, Medical University of Silesia, Katowice, Poland
autor
  • Pharmaceutical Research and Production Plant "Biochefa", Sosnowiec, Poland
Bibliografia
  • Allwood M.C., Kearney M.C. 1998. Compatibility and stability of additives in parenteral nutrition admixtures. Nutrition,.14(9): 697-706.
  • Chanoit G., Lee S., Xi J., Zhu M., McIntosh R.A., Mueller R.A., Norfleet E.A., Xu Z. 2008. Exogenous zinc protects cardiac cells from reperfusion injury by targeting mitochondrial permeability transition pore through inactivation of glycogen synthase kinase-3beta. Am. J. Physiol. Heart Circ. Physiol.,. 295(3): H1227-H1233.
  • Cheng Y., Liu Y.F., Liang J. 2002. Protective effect of zinc: a potent heat shock protein inducer in cold preservation of rat liver. Hepatobiliary Pancreat. Dis. Int.,.1(2): 258-261.
  • Combs G.F., Clark L.C., Turnbull B.W. 2001. An analysis of cancer prevention by selenium. BioFactors, 14: 153-159.
  • Dawud F.A., Eze E.D., Ardja A.A., Isa A.S., Jimoh A., Bashiru M., Malgwi I.S. 2012. Ameliorative effects of vitamin c and zinc in Alloxan-induced diabetes and oxidative stress in wistar rats. Curr. Res. J. Biol. Sci., 4(2): 123-129.
  • Dolińska B., Ostróżka-Cieślik A., Caban A., Rimantas K., Leszczyńska L., Ryszka F. 2012a. Influence of trace elements on stabilization of aqueous solutions of ascorbic acid. Biol. Trace Elem. Res.,.150(1-3): 509-512.
  • Dolińska B., Ostróżka-Cieślik A., Caban A., Cierpka L., Ryszka F. 2012b. Comparing the effect of Biolasol and HTK solutions on maintaining proper homeostasis, indicating the kidney storage efficiency prior to transplantation. Ann. Transplant., 17: 74-78.
  • Ganther H.E., Kraus R.J. 1989. Chemical stability of selenious acid in total parenteral nutrition solutions containing ascorbic acid. JPEN,.13(2): 185-188.
  • Goel A., Chauhan D.P., Dhawan D.K. 2000. Protective effects of zinc in chlorpyrifos induced hepatotoxicity: a biochemical and trace elemental study. Biol. Trace Elem. Res., 74: 171-183.
  • Hardy G., Hardy I. 2004. Selenium: the Se-XY nutraceutical. Nutrition, 20:590-593.
  • Karagulova G., Yue Y., Moreyra A., Boutjdir M., Korichneva I. 2007. Protective role of intracellular zinc in myocardial ischemia/reperfusion is associated with preservation of protein kinase C isoforms. J. Pharmacol. Exp. Ther.,.321(2): 517-525.
  • Karayaylali I., Emr e M., Seyrek N. et al. 2004. Nonsynergistic effects of trimetazidine and selenium combination therapy on renal ischemicreperfusion injury in rats. Adv. Ther., 21: 47-60.
  • Mady F.M., Abou-Taleb A.E., Khaled K.A., Yamasaki K., Iohara D., Taguchi K., Anraku M., Hirayama F., Uekama K., Otagiri M. 2010. Evaluation of carboxymethyl-beta-cyclodextrin with acid function: improvement of chemical stability, oral bioavailability and bitter taste of famotidine. Int. J. Pharm.,.397(1-2): 1-8.
  • McGee C.D., Mascarwnhas M.G., Ostro M.J., Rasallas G., Jeejeebhoy K. 1985. Selenium and vitamin E stability on parenteral solutions. JPEN, 5: 568-570.
  • Ogawa T., Mimura Y. 1999. Antioxidant effect of zinc on acute renal failure induced by ischemia- reperfusion injury in rats. Am. J. Nephrol.,.19(5): 609-614.
  • Osredkar J., Sustar N. 2011. Copper and zinc, biological role and significance of copper/zinc imbalance. J. Clinic. Toxicol., S3: 001.
  • Ostróżka-Cieślik A., Dolińska B., Ryszka F. 2009. Influence of the selected antioxidants on the stability of the Celsior solution used for perfusion and organ preservation purposes. AAPS Pharm. Sci. Tech., 10: 468-475.
  • Poltronieri R., Cevese A., Sbarbati A. 1992. Protective effect of selenium in cardiac ischemia and reperfusion. Cardioscience, 3: 155-160.
  • Powell S.R., Aiuto L., Hall D., Tortolani A.J. 1995. Zinc supplementation enhances the effectiveness of St. Thomas’ Hospital No. 2 cardioplegic solution in an in vitro model of hypothermic cardiac arrest. J. Thorac. Cardiovasc. Surg.,.110(6): 1642-1648.
  • Powell S.R., Nelson R.L., Finnerty J., Alexander D., Pottanat G., Kooker K., Schiff R.J., Moyse J., Teichberg S., Tortolani A.J. 1997. Zinc-bis-histidinate preserves cardiac function in a porcine model of cardioplegic arrest. Ann. Thorac. Surg.,.64(1): 73-80.
  • Powell SR. 2000. The antioxidant properties of zinc. J. Nutr.,.130 (5S): 1447S-1454S. Richard M.J., Ducros V., Forêt M., Arnaud J., Coudray C., Fusselier M., Favier A. 1993. Reversal of selenium and zinc deficiencies in chronic hemodialysis patients by intravenous sodium selenite and zinc gluconate supplementation. Time-course of glutathione peroxidase repletion and lipid peroxidation decrease. Biol. Trace Elem. Res.,.39(2-3): 149-159.
  • Ryszka F., Cierpka L., Dolińska B. 2005. Solution for organs preservation, perfusion and reperfusion. Patent P 375516. (in Polish)
  • Sher L. 2001. Role of thyroid hormones in the effects of selenium on mood, behavior, and cognitive function. Med. Hypotheses.,.57(4): 480-483.
  • Sidhu P., Garg M.L., Dhawan D.K. 2004. Protective effects of zinc on oxidative stress enzymes in liver of protein deficient rats. Nutr. Hosp., 19: 341-347.
  • Soncul H., Kaptanoglu M., Öz E et al. 1994. The role of selenium added to pulmonary preservation solutions in isolated guinea pig lungs. J. Thorac. Cardiovasc. Surg., 108(5): 922-927.
  • Tanguy S., Boucher F., Besse S., Ducros V., Favier A., de Leiris J. 1998. Trace elements and cardioprotection: increasing endogenous glutathione peroxidase activity by oral selenium supplementation in rats limits reperfusion-induced arrhythmias. J. Trace Elem. Med. Biol., 12: 28-38.
  • Treska V., Kuntscher V., Molácek J., Kobr J., Racek J., Trefil L. 2003. Can ischemia-reperfusion syndrome in transplanted kidneys procured from non-heart-beating donors be influenced by adding selenium into the reperfusion solution? An experimental study. Transplant. Proc.,. 35(8): 3125-3127.
  • Venardos K., Harr ison G., Headrick J., Perkins A. 2004. Selenium supplementation and ischemia- reperfusion injury in rats. Redox Rep., 9: 317-320.
  • Zapletal C., Heyne S., Golling M., et al. 2001. Influence of selenium therapy on liver microcirculation after warm ischemia/reperfusion: an intravital microscopy study. Transplant.Proc., 33: 974-975.
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.agro-1e04a681-1141-40d5-9d81-869713ac1f59
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.