Antibacterial activity of (PVP-ZrO2) nanocomposite against pathogenic bacteria

• Autorzy: Abdulrazaq R.A. , Al-Ramadhan Z.A. , Khalaf K.K.
• Języki publikacji: EN

Abstrakty

EN

The antibacterial activity of a PVP-ZrO2 nanocomposite was investigated against pathogenic bacteria S. aureus and K. pneumoniae after antibacterial sensitivity was determined and one isolate was chosen that showed more antibiotic resistance. Herein, the Co-culture technique was used to calculate percent reduction of bacteria. The results that were obtained in this method show that ZrO2 nanoparticles have inhibitory effect against pathogenic bacteria gram negative bacteria and gram positive bacteria - with reduction of growth reaching 100% to both S. aureus and K. pnumoniae at 5, 10, 15, 20 and 25% ZrO2, compared with control. The resistance patterns of S. aureus and K.pnuemonia isolates show the Moxifloxacin (MXF) is the best antibiotic for both bacteria - with sensitivity at 100%, while resistance to Ceftriaxone (CRO) is at 90% S. aureus, and at 80% K. pnumoniae. The polymer-nanocomposite was prepared by weight percentage wt. % of (PVP) being dissolved in (10) ml of distilled water, with weight percentages 5%, 10%, 15%, 20% and 25% of ZrO2 nanoparticles added.

• Wydawca: -
• Czasopismo: World News of Natural Sciences
• Rocznik: 2018
• Tom: 18
• Numer: 2
• Opis fizyczny: p.187-194,fig.,ref.

Twórcy

autor

Abdulrazaq R.A.

• Department of Biology, College of Science, Al-Mustansiriyah University, Baghdad, Iraq

autor

Al-Ramadhan Z.A.

• Department of Physics, College of Education, Al-Mustansiriyah University, Baghdad, Iraq

autor

Khalaf K.K.

• Department of Physics, College of Education, Al-Mustansiriyah University, Baghdad, Iraq

Bibliografia

• [1] Ziaei-Azad, H. and Semagina, N. Bimetallic catalysts: Requirements for stabilizing PVP removal depend on the surface composition. Applied Catalysis A: General. 2014, 482: 327-335.
• [2] Sapir, L.; Stanley, CB.; Harries, D. Properties of Polyvinylpyrrolidone in a Deep Eutectic Solvent. J. Phys. Chem. A 2016, 120 (19): 3253–3259.
• [3] Meija, J., Tyler, B. Coplen, Michael, B, Willi, A. Brand, Paul De Bièvre, Manfred Gröning, Norman E. Holden, Johanna Irrgeher, Robert, D. Loss, Thomas, Walczyk, and Thomas Prohaska; Atomic weights of the elements (IUPAC Technical Report). Pure and Applied Chemistry 2016, 88 (3): 265–91
• [4] Lee, D.B.N, Roberts, M., Bluchel, C.G, Odell R.A. Zirconium: Biomedical and nephrological applications. ASAIO J 2010, 56 (6): 550-556.
• [5] Matthew, J.T. Synthesis of the accessory gene regulator autoinducing peptide in Staphylococcus aureus. University of Iowa, 2012.
• [6] Lin, C.T.; Wu, C.C.; Chen, Y.S.; Lai, Y.C.; Chi, C.; Lin, J.C.; Chen, Y. and Peng, H.L. Fur regulation of the capsular polysaccharide biosynthesis and iron-acquisition systems in Klebsiella pneumoniae CG43. J. Microbiology 2011, 157: 419–429.
• [7] Salman, J.A.S. Antibacterial activity of silver nanoparticles Synthesized by Lactobacillus spp. Against Methicillin Resistant- Staphylococcus aureus. International Journal of Advanced Research 2013: 1(6): 178-184.
• [8] Jiang, J. J; Zhou, H. F; Fang, C. Y. Wang, Z. L; Wang. And S. S. Xie, Adv. Funct. Mater. 17, 1303 (2007).
• [9] Rana, M.A; Anaam, A.H; Arwa, M.A. Antibacterial activity of Zirconium oxide ZrO2 Nanoparticles against some pathogenic bacteria. Journal of Science of Mustansiriyha 2016: vol. 27 (5).
• [10] Jakob U; Gaestel, M; Engel, K; Buchner J. Small heat shock proteins are molecular chaperones. J. Biol. Chem. 1993: 268: 1517-20.
• [11] Gowri S; Gandhi, R.R. and Sundrarajan, M. Structural, Optical, Antibacterial and abtifungal properities of Zirconium Nanoparticles by Biobasal protocol. J. Master. Sci. Technol. 2014: 30(8): 782-790.