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2016 | 19 | 3 |
Tytuł artykułu

Feeding pregnant and lactating mice Rhodiola kirilowii extracts helps to preserve thymus function of their adult progeny

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Plants belonging to Rhodiola kirilowii species, members of Rhodiola genus and Crassulaceae family, grow wildly in Tibet, Mongolia and China mountains and are traditionally used as adaptogens, antidepressants and anti-inflammatory remedies. Nowadays, R. kirilowii is cultivated in some countries, also in Poland. In our previous papers we reported immuno- and angio-modulatory effects of aqueous and hydro-alcoholic extracts of radix and rhizome of this plant in non-pregnant and pregnant mice. The aim of the present study was to evaluate the effect of feeding pregnant and further lactating mice these extracts on selected thymus function parameters in adult progeny. The counts of M-30+ apoptotic cells, in the thymuses obtained from progeny of mice fed during pregnancy and lactation water or 50% water-alcoholic extract of Rhodiola kirilowii, were significantly lower (p<0.05) than apoptotic cells counts observed in the control mice. No significant differences in the counts of IL-7-positive cells in the thymuses obtained from progeny of the control mice and mothers treated with water or hydro-alcohol extracts of Rhodiola kirilowii were observed.
Słowa kluczowe
EN
Wydawca
-
Rocznik
Tom
19
Numer
3
Opis fizyczny
p.581-587,fig.,ref.
Twórcy
autor
  • Department of Regenerative Medicine, Military Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland
autor
  • Department of Regenerative Medicine, Military Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland
autor
  • Department of Regenerative Medicine, Military Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland
  • Biostructure Center, Department of Pathomorphology, Medical University, Chalubinskiego 5, 02-004 Warsaw, Poland
  • Department of Microwave Safety, Military Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland
  • Department of Regenerative Medicine, Military Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland
Bibliografia
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  • Lewicki S, Stankiewicz W, Skopinska-Różewska E, Wilczak J, Leśniak M, Suska M, Siwicki AK, Skopiński P, Zdanowski R (2015) Spleen content of selected polyphenols, splenocytes morphology and function in mice fed Rhodiola kirilowii extracts during pregnancy and lactation. Pol J Vet Sci 18: 847-855.
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  • Siwicki AK, Skopinska-Różewska E, Hartwich M, Wójcik R, Bakuła T, Furmanowa M, Bałan BJ, Sommer E, Mielcarek S, Buchwald W, Krajewska-Patan A, Mścisz A, Mrozikiewicz PM, Bany J (2007) The influence of Rhodiola rosea extracts on non-specific and specific cellular immunity in pigs, rats and mice. Centr Eur J Immunol 32: 84-91.
  • Siwicki AK, Skopińska-Różewska E, Wasiutyński A, Wójcik R, Zdanowski R, Sommer E, Buchwald W, Furmanowa M, Bakuła T, Stankiewicz W (2012) The effect of Rhodiola kirilowii extracts on pigs blood leukocytes metabolic (RBA) and proliferative (LPS) activity, and on the bacterial infection and blood leukocyte number in mice. Centr Eur J Immunol 37: 145-150.
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  • Skopińska-Różewska E, Hartwich M, Siwicki AK, Wasiutyński A, Sommer E, Mazurkiewicz M, Bany J, Skurzak H (2008b) The influence of Rhodiola rosea extracts and rosavin on cutaneous angiogenesis induced in mice after grafting of syngeneic tumor cells. Centr Eur J Immunol 33: 102-107.
  • Skopińska-Rózewska E, Malinowski M, Wasiutyński A, Sommer E, Furmanowa M, Mazurkiewicz M, Siwicki AK (2008c) The influence of Rhodiola quadrifida 50% hydro-alcoholic extract and salidroside on tumor-induced angiogenesis in mice. Pol J Vet Sci 11: 97-104.
  • Skopińska-Różewska E, Bychawska M, Sommer E, Siwicki AK (2008d) The in vivo effect of Rhodiola quadrifida extracts on the metabolic activity of blood granulocytes in mice. Centr Eur J Immunol 33: 179-181.
  • Skopinska-Różewska E, Wójcik R, Siwicki AK, Sommer E, Wasiutyński A, Furmanowa M, Malinowski M, Mazurkiewicz M (2008e) The effect of Rhodiola quadrifida extracts on cellular immunity in mice and rats. Pol J Vet Sci 11: 105-111.
  • Skopinska-Różewska E, Bychawska M, Białas-Chromiec B, Sommer E (2009) The in vivo effect of Rhodiola rosea and Rhodiola quadrifida hydro-alcoholic extracts on chemokinetic activity of spleen lymphocytes in mice. Centr Eur J Immunol 34: 42-45.
  • Skopińska-Różewska E, Bychawska M, Białas-Chromiec B, Sommer E, Furmanowa M, Mrozikiewicz PM, Buchwald W, Mielcarek S, Siwicki AK (2010) The in vivo effect of Rhodiola kirilowii extracts on blood granulocytes metabolic activity in mice. Centr Eur J Immunol 35: 20-24.
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  • Skopińska-Różewska E, Stankiewicz W, Zdanowski R, Siwicki AK, Furmanowa M, Buchwald W, Wasiutyński A (2012) The in vivo effect of Rhodiola quadrifida extracts on the antibody production, blood leukocytes subpopulations and on the bacterial infection in mice. Centr Eur J Immunol 37: 140-144.
  • von Freeden-Jeffry U, Solvason N, Howard M, Murray R (1997) The earliest T lineage-committed cells depend on IL-7 for Bcl-2 expression and normal cell cycle progression. Immunity 7: 147-154.
  • Wójcik R, Siwicki AK, Skopinska-Różewska E, Mścisz A, Mielcarek S, Furmanowa M, Mrozikiewicz PM (2008) The in vitro influence of Rhodiola quadrifida extracts on non-specific cellular immunity in pigs. Centr Eur J Immunol 33: 193-196.
  • Wójcik R, Siwicki AK, Skopińska-Różewska E, Wasiutyński A, Sommer E, Furmanowa M (2009a) The effect of chinese medicinal herb Rhodiola kirilowii extracts on cellular immunity in mice and rats. Pol J Vet Sci 12: 399-405.
  • Wójcik R, Siwicki AK, Skopinska-Różewska E, Bakuła T, Furmanowa M (2009b) The in vitro effect of Rhodiola quadrifida and R. kirilowii extracts on pigs blood lymphocyte response to mitogen ConA. Centr Eur J Immunol 34: 166-170.
  • Wójcik R, Siwicki AK, Skopińska-Różewska E, Buchwald W, FurmanowaM (2009c) The in vitro influence of Rhodiola kirilowii extracts on blood granulocytes potential killing activity (PKA) in pigs. Centr Eur J Immunol 34: 158-161.
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  • Zdanowski R, Lewicki S, Skopińska-Różewska E, Buchwald W, Mrozikiewicz PM, Stankiewicz W (2014) Alcoholand water-based extracts obtained from Rhodiola rosea affect differently the number and metabolic activity of circulating granulocytes in Balb/c mice. Ann Agric Environ Med 21: 120-123.
  • Zdanowski R, Skopińska-Różewska E, Wasiutyński A, Skopiński P, Siwicki AK, Sobiczewska E, Lewicki S, Buchwald W, Kocik J, Stankiewicz W (2012) The effect of Rhodiola kirilowii extracts on tumor-induced angiogenesis in mice. Centr Eur J Immunol 37: 131-139.
Typ dokumentu
Bibliografia
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Identyfikator YADDA
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