Feeding pregnant and lactating mice Rhodiola kirilowii extracts helps to preserve thymus function of their adult progeny

• Autorzy: Bien K. , Lewicki S. , Zdanowski R. , Skopinska-Rozewska E. , Krzyzowska M.
• Języki publikacji: EN

Abstrakty

EN

Plants belonging to Rhodiola kirilowii species, members of Rhodiola genus and Crassulaceae family, grow wildly in Tibet, Mongolia and China mountains and are traditionally used as adaptogens, antidepressants and anti-inflammatory remedies. Nowadays, R. kirilowii is cultivated in some countries, also in Poland. In our previous papers we reported immuno- and angio-modulatory effects of aqueous and hydro-alcoholic extracts of radix and rhizome of this plant in non-pregnant and pregnant mice. The aim of the present study was to evaluate the effect of feeding pregnant and further lactating mice these extracts on selected thymus function parameters in adult progeny. The counts of M-30+ apoptotic cells, in the thymuses obtained from progeny of mice fed during pregnancy and lactation water or 50% water-alcoholic extract of Rhodiola kirilowii, were significantly lower (p<0.05) than apoptotic cells counts observed in the control mice. No significant differences in the counts of IL-7-positive cells in the thymuses obtained from progeny of the control mice and mothers treated with water or hydro-alcohol extracts of Rhodiola kirilowii were observed.

• Wydawca: -
• Czasopismo: Polish Journal of Veterinary Sciences
• Rocznik: 2016
• Tom: 19
• Numer: 3
• Opis fizyczny: p.581-587,fig.,ref.

Twórcy

autor

Bien K.

• Department of Regenerative Medicine, Military Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland

autor

Lewicki S.

• Department of Regenerative Medicine, Military Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland

autor

Zdanowski R.

• Department of Regenerative Medicine, Military Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland

autor

Skopinska-Rozewska E.

• Biostructure Center, Department of Pathomorphology, Medical University, Chalubinskiego 5, 02-004 Warsaw, Poland
• Department of Microwave Safety, Military Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland

autor

Krzyzowska M.

• Department of Regenerative Medicine, Military Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland

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Identyfikatory

DOI

10.1515/pjvs-2016-0073