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2012 | 15 | 3 |
Tytuł artykułu

Acid-base indicators in the venous and arterial blood of horses affected by recurrent airway obstruction (RAO)

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The acid-base equilibrium is closely linked to gas exchange in the lungs, and respiratory exchange ratios are used to evaluate respiratory effectiveness and tissue oxygen levels. Acid-base indicators are determined in both arterial and venous blood samples. This study compares the usefulness of acid-base indicators of venous and arterial blood in monitoring the condition of horses with recurrent airway obstruction. Prior to treatment involving bronchodilating glucocorticoids, expectorant and mucolytic drugs, more pronounced changes were observed in venous blood (pH 7.283, pCO2 61.92 mmHg, pO2 35.541 mmHg, HCO3 - 31.933 mmHg, BE 2.933 mmol/l, O2SAT 58.366%, ctCO2 38.333 mmol/l) than in arterial blood (pH 7.309, pCO2 53.478 mmHg, pO2 90.856 mmHg, HCO3 - 28.50 mmHg, BE 3.133 mmol/l, O2SAT 93.375%, ctCO2 31.652 mmol/l), indicating compensated respiratory acidosis. The improvement of respiratory efficiency minimized acidosis symptoms in both venous blood (pH 7.365, pCO2 43.55 mmHg, pO2 47.80 mmHg, HCO3 - 30.325 mmHg, BE 3.050 mmol/l, O2SAT 80.10%, ctCO2 29.80 mmol/l) and arterial blood (pH 7.375, pCO2 39.268 mmHg, pO2 98.476 mmHg, HCO3 - 26.651 mmHg, BE 4.956 mmol/l, O2SAT 98.475%, ctCO2 28.131 mmol/l). Venous blood parameters were marked by greater deviations from mean values, both before and after treatment. Acid-base indicators determined in venous blood are indicative of respiratory disturbances, but they do not support a comprehensive evaluation of gas exchange in the lungs.
Wydawca
-
Rocznik
Tom
15
Numer
3
Opis fizyczny
p.463-467,ref.
Twórcy
autor
  • Department and Clinic of Internal Diseases, Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowskiego 14, 10-719 Olsztyn, Poland
autor
Bibliografia
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  • Cambier C, Di Passio N, Clerbaux T, Amory H, Marville V, Detry B, Frans A, Gustin P (2005) Blood-oxygen binding in healthy Standardbred horses. Vet J 169: 251-256.
  • Chevalier H, Divers TJ (2003) Pulmonary Dysfunction in Adult Horses in the Intensive Care. Unit Clinl Tech Eq Pract 2: 165-177.
  • Divers TJ (2003) Monitoring Tissue Oxygenation in the ICU Patient. Clinl Tech Eq Pract 2: 138-144.
  • Ferro E, Ferrucci F, Zucca E, Di Fabio V, Castoldi S (2002) Arterial blood gas analysis in 53 racehorses with a diagnosis of small airway inflamatory disease (SAID). J Eq Vet Sci 22: 165-168.
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  • Johnson PJ (1995) Electrolyte and acid-base disturbances in the horse. Vet Clin North Am Equine Pract 11: 491-514.
  • McKeever KH (2005) Can feed cause a positive blood test in racehorses? Some recent information on the effect of dietary supplements on plasma tCO2 cocncentration in horses. Adv Eq Nutr 3: 69-76.
  • Moe OW, Fuster D (2003) Clinical acid-base pathophysiology: disorders of plasma anion gap. Best Pract Res Clin Endocrinol Metab 17: 559-574.
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  • Piccione G, Ferrantelli V, Fazio F, Percipalle M, Caola G (2004) Blood-gas profile in the show jumper undergoing increasing workloads during a 2-day event. Comp Clin Pathol 13: 43-50.
  • Ryhner T, Muller N, Balmer V, Gerber V (2008) Increased mucus accumulation in horses chronically affected with recurrent airway obstruction is not associated with up-regulation of CLCA1, EGFR, MUC5AC, Bcl-2, IL-13 and INF-gamma expression. Vet Immunol Immunopathol 125: 8-17.
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  • Stopyra A (2002) Gasometry indices and the activity of selected enzymes in horse serum during extreme exertion. Med Weter 58: 543-548.
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.agro-1c24db18-3ab6-4fd7-93d4-c0e5b96a7d00
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