Białka regulujące proces dojrzewania oocytów u ssaków

• Autorzy: Swierczewska M. , Zaorska K. , Kempisty B. , Nowicki M.

Warianty tytułu

EN

Proteins regulating the maturation of oocytes in mammals

• Języki publikacji: PL

Abstrakty

EN

In this review, the molecular aspects of meiotic division and characteristics of proteins involved in mammalian oocytes maturation have been presented. Moreover, the role of competition has also been shown. The mammalian oocyte’s maturation is divided into: (i) nuclear maturation; (ii) cytoplasmic maturation; and (iii) genomic maturation. The maturation processes involves the stages associated with stored proteins and mRNA as well as the inherited changes in genomic DNA methylation. The proper procedure of all stages of maturation influences the achievement by oocytes of full developmental competence and fertilization ability. Both of these processes are associated with attaining by the embryos the ability of growth and development following embryonic genome activation (EGA). The stages of oocyte’s maturation are regulated by the expression of specific genes encoding proteins that are expressed during early folliculo-, and oogenesis, and is species dependent. The most important proteins regulating the process of oocytes maturation involves the following: transforming growth factor of the large super family group (TGF), connexins (Cx), mitogen activated protein kinase (MAPK), protein kinase A (PKA) and epidermal growth factor (EGF).

Słowa kluczowe

PL

ssaki; oocyty; dojrzewanie oocytow; regulacja; bialka; koneksyny; ligand kit; czynnik wzrostu transformujacy beta

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2012
• Tom: 68
• Numer: 11
• Opis fizyczny: s.666-671,rys.,bibliogr.

Twórcy

autor

Swierczewska M.

• Katedra i Zakład Histologii i Embriologii, Wydział Lekarski II, Uniwersytet Medyczny im.Karola Marcinkowskiego w Poznaniu, ul.Święcickiego 6, 60-781 Poznań

autor

Zaorska K.

autor

Kempisty B.

autor

Nowicki M.

Bibliografia

• 1. Ackert C. L., Gittens J. E., O’Brien M. J., Eppig J. J., Kidder G. M.: Intercellular communication via connexin43 gap junctions is required for ovarian folliculogenesis in the mouse. Dev. Biol. 2001, 233, 258-270.
• 2. Aerts J. M., Bols P. E.: Ovarian follicular dynamics: a review with emphasis on the bovine species. Part I: Folliculogenesis and pre-antral follicle development. Reprod. Domest. Anim. 2010, 45, 171-179.
• 3. Brevini T. A., Cillo F., Antonini S., Gandolfi F.: Cytoplasmic remodelling and the acquisition of developmental competence in pig oocytes. Anim. Reprod. Sci. 2007, 98, 23-38.
• 4. Buratini J., Price C. A.: Follicular somatic cell factors and follicle development. Reprod. Fertil. Dev. 2011, 23, 32-39.
• 5. Carabatsos M. J., Sellitto C., Goodenough D. A., Albertini D. F.: Oocyte-granulosa cell heterologous gap junctions are required for the coordination of nuclear and cytoplasmic meiotic competence. Dev. Biol. 2000, 226, 167-179.
• 6. Cecconi S., Ciccarelli C., Barberi M., Macchiarelli G., Canipari R.: Granulosa cell-oocyte interactions. Eur. J. Obstet. Gynecol. Reprod. Biol. 2004, 115S, S19-S22.
• 7. Dekel N.: Cellular, biochemical and molecular mechanisms regulating oocyte maturation. Moll. Cell. Endocrinol. 2005, 234, 19-25.
• 8. Dekel N.: Protein phosphorylation/dephosphorylation in the meiotic cell cycle of mammalian oocytes. Rev. Reprod. 1996, 1, 82-88.
• 9. Downs S. M., Ya R., Davis C. C.: Role of AMPK throughout meiotic maturation in the mouse oocyte: evidence for promotion of polar body formation and suppression of premature activation. Mol. Reprod. Dev. 2010, 77, 888-899.
• 10. Feng W. G., Sui H. S., Han Z. B., Chang Z. L., Zhou P., Liu D. J., Bao S., Tan J. H.: Effects of follicular atresia and size on the developmental competence of bovine oocytes: a study using the well-in-drop culture system. Theriogenology 2007, 67, 1339-1350.
• 11. Gilchrist R. B., Lane M., Thompson J. G.: Oocyte-secreted factors: regulators of cumulus cell function and oocyte quality. Hum. Reprod. Update 2008, 14, 159-177.
• 12. Hashimoto N., Watanabe N., Furuta Y., Tamemoto H., Sagata N., Yokoyama M., Okazaki K., Nagayoshi M., Takeda N., Ikawa Y., Aizawa S.: Parthenogenetic activation of oocytes in c-mos-deficient mice. Nature 1994, 370, 68-71.
• 13. Hunter M. G., Paradis F.: Intra-follicular regulatory mechanisms in the porcine ovary. Soc. Reprod. Fertil. Suppl. 2009, 66, 149-164.
• 14. Hurk R. van den, Zhao J.: Formation of mammalian oocytes and their growth, differentiation and maturation within ovarian follicles. Theriogenology 2005, 63, 1717-1751.
• 15. Hutt K. J., Albertini D. F.: An oocentric view of folliculogenesis and embryogenesis. Reprod. Biomed. Online 2007, 14, 758-764.
• 16. Jałocha I., Gabryś M. S., Bal J.: Rola protoonkogenu c-mos w regulacji procesu dojrzewania komórki jajowej. Postępy Hig. Med. Dośw. 2010, 64, 636-641.
• 17. Juengel J. L., Bodensteiner K. J., Heath D. A., Hudson N. L., Moeller C. L., Smith P., Galloway S. M., Davis G. H., Sawyer H. R., McNatty K. P.: Physiology of GDF9 and BMP15 signalling molecules. Anim. Reprod. Sci. 2004, 82-83, 447-460.
• 18. Juengel J. L., McNatty K. P.: The role of proteins of the transforming growth factor-beta superfamily in the intraovarian regulation of follicular development. Hum. Reprod. Update 2005, 11, 143-160.
• 19. Kempisty B., Antosik P., Bukowska D., Jackowska M., Lianeri M., Jaśkowski J. M., Jagodziński P. P.: Analysis of selected transcript levels in porcine spermatozoa, oocytes, zygotes and two-cell stage embryos. Reprod. Fertil. Dev. 2008, 20, 513-518.
• 20. Kempisty B., Antosik P., Bukowska D., Jackowska M., Lianeri M., Jaśkowski J. M., Jagodziński P. P.: Assessment of zona pellucida glycoprotein and integrin transcript contents in porcine oocytes. Reprod. Biol. 2009, 9, 71-78.
• 21. Kempisty B., Jackowska M., Piotrowska H., Antosik P., Woźna M., Bukowska D., Brüssow K. P., Jaśkowski J. M.: Zona pellucida glycoprotein 3 (pZP3) and integrin β (ITGB2) mRNA and protein expression in porcine oocytes after single and double exposure to brilliant cresyl blue test. Theriogenology 2011, 75, 1525-1535.
• 22. Knight P. G., Glister C.: TGF-beta superfamily members and ovarian follicle development. Reproduction 2006, 132, 191-206.
• 23. Ka H. H., Sawai K., Wang W. H., Im K. S., Niwa K.: Amino acids in maturation medium and presence of cumulus cells at fertilization promote male pronuclear formation in porcine oocytes matured and penetrated in vitro. Biol. Reprod. 1997, 57, 1478-1483.
• 24. Lee G. S., Kim H. S., Hwang W. S., Hyun S. H.: Characterization of porcine growth differentiation factor-9 and its expression in oocyte maturation. Mol. Reprod. Dev. 2008, 75, 707-714.
• 25. Liang C. G., Su Y. Q., Fan H. Y., Schatten H., Sun Q. Y.: Mechanisms regulating oocyte meiotic resumption: roles of mitogen-activated protein kinase. Mol. Endocrinol. 2007, 21, 2037-2055.
• 26. Marteil G., Richard-Parpaillon L., Kubiak J. Z.: Role of oocyte quality in meiotic maturation and embryonic development. Reprod. Biol. 2009, 9, 203-224.
• 27. Mayes M. A., Laforest M. F., Guillemette C., Gilchrist R. B., Richard F. J.: Adenosine 5'-monophosphate kinase-activated protein kinase (PRKA) activators delay meiotic resumption in porcine oocytes. Biol. Reprod. 2007, 76, 589-597.
• 28. McLaughlin E. A., McIver S. C.: Awakening the oocyte: controlling primordial follicle development. Reproduction 2009, 137, 1-11.
• 29. Mehlmann L. M.: Oocyte-specific expression of Gpr3 is required for the maintenance of meiotic arrest in mouse oocytes. Dev. Biol. 2005, 288, 397-404.
• 30. Mermillod P., Dalbičs-Tran R., Uzbekova S., Thélie A., Traverso J. M., Perreau C., Papillier P., Monget P.: Factors affecting oocyte quality: who is driving the follicle? Reprod. Domest. Anim. 2008, 43, 293-400.
• 31. Moore R. K., Shimasaki S.: Molecular biology and physiological role of the oocyte factor, BMP-15. Mol. Cell. Endocrinol. 2005, 29, 67-73.
• 32. Mottershead D. G., Watson A. J.: Oocyte peptides as paracrine tools for ovarian stimulation and oocyte maturation. Mol. Hum. Reprod. 2009, 15, 789-794.
• 33. Opiela J., Kątska-Książkiewicz L.: Charakterystyka zdolności rozwojowej oocytów ssaków w aspekcie zapłodnienia i rozwoju zarodkowego. Cz. II. Regulacja dojrzałości cytoplazmatycznej i genomowej. Biotechnologia 2005, 2, 151-162.
• 34. Otsuka F., McTavish K. J., Shimasaki S.: Integral role of GDF-9 and BMP-15 in ovarian function. Mol. Reprod. Dev. 2011, 78, 9-21.
• 35. Sagata N.: Meiotic metaphase arrest in animal oocytes: its mechanisms and biological significance. Trends Cell. Biol. 1996, 6, 22-28.
• 36. Sirotkin A. V., Taradajnik T. E., Makarevich A. V., Bulla J.: Effect of follicular cells, IGF-I and tyrosine kinase blockers on oocyte maturation. Anim. Reprod. Sci. 1998, 51, 333-344.
• 37. Sun Q. Y., Nagai T.: Molecular mechanisms underlying pig oocyte maturation and fertilization. J. Reprod. Dev. 2003, 49, 347-359.
• 38. Trounson A., Anderiesz C., Jones G.: Maturation of human oocytes in vitro and their developmental competence. Reproduction 2001, 121, 51-75.
• 39. Webb R., Campbell B. K.: Development of the dominant follicle: mechanisms of selection and maintenance of oocyte quality. Soc. Reprod. Fertil. Suppl. 2007, 64, 141-163.
• 40. Yeo C. X., Gilchrist R. B., Thompson J. G., Lane M.: Exogenous growth differentiation factor 9 in oocyte maturation media enhances subsequent embryo development and fetal viability in mice. Hum. Reprod. 2008, 23, 67-73.